We will be switching to the new UniProt website on Tuesday, June 28. Please explore and share your feedback.
Take me to UniProt BETA
UniProtKB - P77268 (DDPD_ECOLI)
Protein
Probable D,D-dipeptide transport ATP-binding protein DdpD
Gene
ddpD
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport (PubMed:9097039).
Probably responsible for energy coupling to the transport system.
1 PublicationRegions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 42 – 49 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- dipeptide transport Source: ComplexPortal
- protein transport Source: UniProtKB-KW
Keywordsi
Biological process | Peptide transport, Protein transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:YDDP-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.5.38, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Probable D,D-dipeptide transport ATP-binding protein DdpD |
Gene namesi | Name:ddpD1 Publication Synonyms:yddP Ordered Locus Names:b1484, JW1479 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane Curated; Peripheral membrane protein Curated
Plasma Membrane
- ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing Source: ComplexPortal
Other locations
- membrane Source: ComplexPortal
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000093165 | 1 – 328 | Probable D,D-dipeptide transport ATP-binding protein DdpDAdd BLAST | 328 |
Proteomic databases
PaxDbi | P77268 |
PRIDEi | P77268 |
Expressioni
Inductioni
Induced by RpoS in stationary phase.1 Publication
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (DdpD and DdpF), two transmembrane proteins (DdpB and DdpC) and a solute-binding protein (DdpA).
CuratedProtein-protein interaction databases
BioGRIDi | 4260962, 121 interactors |
ComplexPortali | CPX-4321, Dipeptide ABC transporter complex |
DIPi | DIP-11669N |
IntActi | P77268, 9 interactors |
STRINGi | 511145.b1484 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 257 | ABC transporterPROSITE-ProRule annotationAdd BLAST | 252 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily.Curated
Phylogenomic databases
eggNOGi | COG0444, Bacteria |
HOGENOMi | CLU_000604_1_23_6 |
InParanoidi | P77268 |
OMAi | QMTEVII |
PhylomeDBi | P77268 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR013563, Oligopep_ABC_C IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit PF08352, oligo_HPY, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01727, oligo_HPY, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P77268-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTQPVLDIQQ LHLSFPGFNG DVHALNNVSL QINRGEIVGL VGESGSGKSV
60 70 80 90 100
TAMLIMRLLP TGSYCVHRGQ ISLLGEDVLN AREKQLRQWR GARVAMIFQE
110 120 130 140 150
PMTALNPTRR IGLQMMDVIR HHQPISRREA RAKAIDLLEE MQIPDAVEVM
160 170 180 190 200
SRYPFELSGG MRQRVMIALA FSCEPQLIIA DEPTTALDVT VQLQVLRLLK
210 220 230 240 250
HKARASGTAV LFISHDMAVV SQLCDSVYVM YAGSVIESGV TADVIHHPRH
260 270 280 290 300
PYTIGLLQCA PEHGVPRQLL PAIPGTVPNL THLPDGCAFR DRCYAAGAQC
310 320
ENVPALTACG DNNQRCACWY PQQEVISV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74557.1 AP009048 Genomic DNA Translation: BAA15139.1 |
PIRi | G64901 |
RefSeqi | NP_416001.1, NC_000913.3 WP_000193547.1, NZ_SSZK01000038.1 |
Genome annotation databases
EnsemblBacteriai | AAC74557; AAC74557; b1484 BAA15139; BAA15139; BAA15139 |
GeneIDi | 946002 |
KEGGi | ecj:JW1479 eco:b1484 |
PATRICi | fig|1411691.4.peg.783 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74557.1 AP009048 Genomic DNA Translation: BAA15139.1 |
PIRi | G64901 |
RefSeqi | NP_416001.1, NC_000913.3 WP_000193547.1, NZ_SSZK01000038.1 |
3D structure databases
AlphaFoldDBi | P77268 |
SMRi | P77268 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260962, 121 interactors |
ComplexPortali | CPX-4321, Dipeptide ABC transporter complex |
DIPi | DIP-11669N |
IntActi | P77268, 9 interactors |
STRINGi | 511145.b1484 |
Protein family/group databases
TCDBi | 3.A.1.5.38, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P77268 |
PRIDEi | P77268 |
Genome annotation databases
EnsemblBacteriai | AAC74557; AAC74557; b1484 BAA15139; BAA15139; BAA15139 |
GeneIDi | 946002 |
KEGGi | ecj:JW1479 eco:b1484 |
PATRICi | fig|1411691.4.peg.783 |
Organism-specific databases
EchoBASEi | EB3548 |
Phylogenomic databases
eggNOGi | COG0444, Bacteria |
HOGENOMi | CLU_000604_1_23_6 |
InParanoidi | P77268 |
OMAi | QMTEVII |
PhylomeDBi | P77268 |
Enzyme and pathway databases
BioCyci | EcoCyc:YDDP-MONOMER |
Miscellaneous databases
PROi | PR:P77268 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR013563, Oligopep_ABC_C IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit PF08352, oligo_HPY, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01727, oligo_HPY, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DDPD_ECOLI | |
Accessioni | P77268Primary (citable) accession number: P77268 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | February 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 154 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families