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Entry version 123 (11 Dec 2019)
Sequence version 2 (21 Jun 2004)
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Protein

Putative uncharacterized protein YaiT

Gene

yaiT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein uncertaini <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Could be the product of a pseudogene. The gene coding for this protein is interrupted by a IS3B element between amino acids 486 and 487.Curated

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ECOL316407:JW0362-MONOMER
ECOL316407:JW5051-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative uncharacterized protein YaiT
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yaiT
Ordered Locus Names:b4580, JW0362/JW5051
ORF Names:b0371, b0374
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000271128 – 968Putative uncharacterized protein YaiTAdd BLAST941

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P77199

PRoteomics IDEntifications database

More...
PRIDEi
P77199

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4259480, 311 interactors
4259820, 219 interactors

Protein interaction database and analysis system

More...
IntActi
P77199, 1 interactor

STRING: functional protein association networks

More...
STRINGi
316407.85674512

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini703 – 968AutotransporterPROSITE-ProRule annotationAdd BLAST266

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Signal

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000117445

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P77199

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.128.130, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005546 Autotransporte_beta
IPR036709 Autotransporte_beta_dom_sf
IPR006315 OM_autotransptr_brl
IPR011050 Pectin_lyase_fold/virulence
IPR004899 Pertactin_central
IPR003991 Pertactin_virulence_factor

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03797 Autotransporter, 1 hit
PF03212 Pertactin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01484 PRTACTNFAMLY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00869 Autotransporter, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103515 SSF103515, 1 hit
SSF51126 SSF51126, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01414 autotrans_barl, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51208 AUTOTRANSPORTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P77199-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHSWKKKLVV SQLALACTLA ITSQANAANY DTWTYIDNPV TALDWDHMDK
60 70 80 90 100
AGTVDGNYVN YSGFVYYNNT NGDFDQSFNG DTVNGTISTY YLNHDYADST
110 120 130 140 150
ANQLDISNSV IHGSITSMLP GGYYDRFDAD GNNLGGYDFY TDAVVDTHWR
160 170 180 190 200
DGDVFTLNIA NTTIDDDYEA LYFTDSYKDG DVTKHTNETF DTSEGVAVNL
210 220 230 240 250
DVESNINISN NSRVAGIALS QGNTYNETYT TESHTWDNNI SVKDSTVTSG
260 270 280 290 300
SNYILDSNTY GKTGHFGNSD EPSDYAGPGD VAMSFTASGS DYAMKNNVFL
310 320 330 340 350
SNSTLMGDVA FTSTWNSNFD PNGHDSNGDG VKDTNGGWTD DSLNVDELNL
360 370 380 390 400
TLDNGSKWVG QAIYNVAETS AMYDVATNSL TPDATYENND WKRVVDDKVF
410 420 430 440 450
QSGVFNVALN NGSEWDTTGR SIVDTLTVNN GSQVNVSESK LTSDTIDLTN
460 470 480 490 500
GSSLNIGEDG YVDTDHLTIN SYSTVALTES TGWGADYNLY ANTITVTNGG
510 520 530 540 550
VLDVNVDQFD TEAFRTDKLE LTSGNIADHN GNVVSGVFDI HSSDYVLNAD
560 570 580 590 600
LVNDRTWDTS KSNYGYGIVA MNSDGHLTIN GNGDVDNGTE LDNSSVDNVV
610 620 630 640 650
AATGNYKVRI DNATGAGAIA DYKDKEIIYV NDVNSNATFS AANKADLGAY
660 670 680 690 700
TYQAEQRGNT VVLQQMELTD YANMALSIPS ANTNIWNLEQ DTVGTRLTNS
710 720 730 740 750
RHGLADNGGA WVSYFGGNFN GDNGTINYDQ DVNGIMVGVD TKIDGNNAKW
760 770 780 790 800
IVGAAAGFAK GDMNDRSGQV DQDSQTAYIY SSAHFANNVF VDGSLSYSHF
810 820 830 840 850
NNDLSATMSN GTYVDGSTNS DAWGFGLKAG YDFKLGDAGY VTPYGSVSGL
860 870 880 890 900
FQSGDDYQLS NDMKVDGQSY DSMRYELGVD AGYTFTYSED QALTPYFKLA
910 920 930 940 950
YVYDDSNNDN DVNGDSIDNG TEGSAVRVGL GTQFSFTKNF SAYTDANYLG
960
GGDVDQDWSA NVGVKYTW
Length:968
Mass (Da):104,725
Last modified:June 21, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i313695AC5ED735FE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U73857 Genomic DNA Translation: AAB18094.1 Sequence problems.
U73857 Genomic DNA Translation: AAB18097.1 Sequence problems.
U00096 Genomic DNA No translation available.
AP009048 Genomic DNA Translation: BAE76152.1 Sequence problems.
AP009048 Genomic DNA Translation: BAE76155.1 Sequence problems.

Protein sequence database of the Protein Information Resource

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PIRi
C64765
F64765

NCBI Reference Sequences

More...
RefSeqi
WP_000556438.1, NZ_LN832404.1
WP_000556441.1, NZ_CP014272.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
BAE76152; BAE76152; BAE76152
BAE76155; BAE76155; BAE76155

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW0362
ecj:JW5051

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA Translation: AAB18094.1 Sequence problems.
U73857 Genomic DNA Translation: AAB18097.1 Sequence problems.
U00096 Genomic DNA No translation available.
AP009048 Genomic DNA Translation: BAE76152.1 Sequence problems.
AP009048 Genomic DNA Translation: BAE76155.1 Sequence problems.
PIRiC64765
F64765
RefSeqiWP_000556438.1, NZ_LN832404.1
WP_000556441.1, NZ_CP014272.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi4259480, 311 interactors
4259820, 219 interactors
IntActiP77199, 1 interactor
STRINGi316407.85674512

Proteomic databases

jPOSTiP77199
PRIDEiP77199

Genome annotation databases

EnsemblBacteriaiBAE76152; BAE76152; BAE76152
BAE76155; BAE76155; BAE76155
KEGGiecj:JW0362
ecj:JW5051

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB3373

Phylogenomic databases

HOGENOMiHOG000117445
PhylomeDBiP77199

Enzyme and pathway databases

BioCyciECOL316407:JW0362-MONOMER
ECOL316407:JW5051-MONOMER

Family and domain databases

Gene3Di2.40.128.130, 1 hit
InterProiView protein in InterPro
IPR005546 Autotransporte_beta
IPR036709 Autotransporte_beta_dom_sf
IPR006315 OM_autotransptr_brl
IPR011050 Pectin_lyase_fold/virulence
IPR004899 Pertactin_central
IPR003991 Pertactin_virulence_factor
PfamiView protein in Pfam
PF03797 Autotransporter, 1 hit
PF03212 Pertactin, 1 hit
PRINTSiPR01484 PRTACTNFAMLY
SMARTiView protein in SMART
SM00869 Autotransporter, 1 hit
SUPFAMiSSF103515 SSF103515, 1 hit
SSF51126 SSF51126, 1 hit
TIGRFAMsiTIGR01414 autotrans_barl, 1 hit
PROSITEiView protein in PROSITE
PS51208 AUTOTRANSPORTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYAIT_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P77199
Secondary accession number(s): P71312
, P75700, Q2MC51, Q2MC54
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: June 21, 2004
Last modified: December 11, 2019
This is version 123 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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