UniProtKB - P77156 (YDCU_ECOLI)
Protein
Inner membrane ABC transporter permease protein YdcU
Gene
ydcU
Organism
Escherichia coli (strain K12)
Status
Functioni
Probably part of the ABC transporter complex YdcSTUV. Probably responsible for the translocation of the substrate across the membrane.Curated
GO - Biological processi
- transmembrane transport Source: InterPro
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:YDCU-MONOMER MetaCyc:YDCU-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.11.9, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Inner membrane ABC transporter permease protein YdcUCurated |
Gene namesi | Name:ydcU Ordered Locus Names:b1442, JW1437 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane 1 Publication; Multi-pass membrane protein Sequence analysis
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 25 | CytoplasmicCuratedAdd BLAST | 25 | |
Transmembranei | 26 – 46 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 47 – 92 | PeriplasmicCuratedAdd BLAST | 46 | |
Transmembranei | 93 – 113 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 114 – 122 | CytoplasmicCurated | 9 | |
Transmembranei | 123 – 143 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 144 – 154 | PeriplasmicCuratedAdd BLAST | 11 | |
Transmembranei | 155 – 175 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 176 – 187 | CytoplasmicCuratedAdd BLAST | 12 | |
Transmembranei | 188 – 208 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 209 – 230 | PeriplasmicCuratedAdd BLAST | 22 | |
Transmembranei | 231 – 251 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 252 | CytoplasmicCurated | 1 | |
Transmembranei | 253 – 273 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 274 – 283 | PeriplasmicCurated | 10 | |
Transmembranei | 284 – 304 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 305 – 313 | Cytoplasmic1 Publication | 9 |
GO - Cellular componenti
- integral component of plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePathology & Biotechi
Disruption phenotypei
Inactivation of the gene does not significantly affect natural transformation.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000060242 | 1 – 313 | Inner membrane ABC transporter permease protein YdcUAdd BLAST | 313 |
Proteomic databases
PaxDbi | P77156 |
PRIDEi | P77156 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260191, 93 interactors |
ComplexPortali | CPX-4446, YdcSTUV ABC transporter complex |
STRINGi | 511145.b1442 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 87 – 302 | ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST | 216 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1176, Bacteria |
HOGENOMi | CLU_016047_18_1_6 |
InParanoidi | P77156 |
PhylomeDBi | P77156 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
i Sequence
Sequence statusi: Complete.
P77156-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAMNVLQSPS RPGLGKVSGF FWHNPGLGLF LLLLGPLMWF GIVYFGSLLT
60 70 80 90 100
LLWQGFYTFD DFTMSVTPEL TLANIRALFN PANYDIILRT LTMAVAVTIA
110 120 130 140 150
SAILAFPMAW YMARYTSGKM KAFFYIAVML PMWASYIVKA YAWTLLLAKD
160 170 180 190 200
GVAQWFLQHL GLEPLLTAFL TLPAVGGNTL STSGLGRFLV FLYIWLPFMI
210 220 230 240 250
LPVQAALERL PPSLLQASAD LGARPRQTFR YVVLPLAIPG IAAGSIFTFS
260 270 280 290 300
LTLGDFIVPQ LVGPPGYFIG NMVYSQQGAI GNMPMAAAFT LVPIILIALY
310
LAFVKRLGAF DAL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74524.1 AP009048 Genomic DNA Translation: BAA15071.1 |
PIRi | E64896 |
RefSeqi | NP_415959.1, NC_000913.3 WP_001251304.1, NZ_SSZK01000021.1 |
Genome annotation databases
EnsemblBacteriai | AAC74524; AAC74524; b1442 BAA15071; BAA15071; BAA15071 |
GeneIDi | 945976 |
KEGGi | ecj:JW1437 eco:b1442 |
PATRICi | fig|1411691.4.peg.826 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74524.1 AP009048 Genomic DNA Translation: BAA15071.1 |
PIRi | E64896 |
RefSeqi | NP_415959.1, NC_000913.3 WP_001251304.1, NZ_SSZK01000021.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4260191, 93 interactors |
ComplexPortali | CPX-4446, YdcSTUV ABC transporter complex |
STRINGi | 511145.b1442 |
Protein family/group databases
TCDBi | 3.A.1.11.9, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P77156 |
PRIDEi | P77156 |
Genome annotation databases
EnsemblBacteriai | AAC74524; AAC74524; b1442 BAA15071; BAA15071; BAA15071 |
GeneIDi | 945976 |
KEGGi | ecj:JW1437 eco:b1442 |
PATRICi | fig|1411691.4.peg.826 |
Organism-specific databases
EchoBASEi | EB3527 |
Phylogenomic databases
eggNOGi | COG1176, Bacteria |
HOGENOMi | CLU_016047_18_1_6 |
InParanoidi | P77156 |
PhylomeDBi | P77156 |
Enzyme and pathway databases
BioCyci | EcoCyc:YDCU-MONOMER MetaCyc:YDCU-MONOMER |
Miscellaneous databases
PROi | PR:P77156 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YDCU_ECOLI | |
Accessioni | P77156Primary (citable) accession number: P77156 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | February 1, 1997 | |
Last modified: | December 2, 2020 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families