UniProtKB - P76773 (OMPL_ECOLI)
Protein
Porin OmpL
Gene
ompL
Organism
Escherichia coli (strain K12)
Status
Functioni
Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown.1 Publication
Caution
In contrast to PubMed:11080145, PubMed:12660153 demonstrates that OmpL actually plays no perceptible role in modulating redox potential in the periplasm of E.coli.Curated
GO - Molecular functioni
- porin activity Source: EcoCyc
GO - Biological processi
- arabinose transmembrane transport Source: EcoliWiki
- galactose transmembrane transport Source: EcoliWiki
- glucose import Source: EcoliWiki
- oligosaccharide transport Source: GO_Central
Keywordsi
Molecular function | Porin |
Biological process | Ion transport, Sugar transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:G7814-MONOMER |
Protein family/group databases
TCDBi | 1.B.35.2.2, the oligogalacturonate-specific porin (kdgm) family |
Names & Taxonomyi
Protein namesi | Recommended name: Porin OmpL |
Gene namesi | Name:ompL Synonyms:yshA Ordered Locus Names:b3875, JW3846 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Other locations
- Cell outer membrane 1 Publication
Other locations
- cell outer membrane Source: EcoliWiki
- integral component of cell outer membrane Source: GO_Central
- pore complex Source: UniProtKB-KW
Keywords - Cellular componenti
Cell outer membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 20 | 1 PublicationAdd BLAST | 20 | |
ChainiPRO_0000016605 | 21 – 230 | Porin OmpLAdd BLAST | 210 |
Proteomic databases
PaxDbi | P76773 |
PRIDEi | P76773 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262635, 212 interactors |
IntActi | P76773, 21 interactors |
STRINGi | 511145.b3875 |
Family & Domainsi
Sequence similaritiesi
Belongs to the oligogalacturonate-specific porin KdgM (TC 1.B.35) family. OmpL subfamily. [View classification]Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane beta strandPhylogenomic databases
eggNOGi | COG1452, Bacteria |
HOGENOMi | CLU_103714_0_0_6 |
Family and domain databases
InterProi | View protein in InterPro IPR009331, Oligogalacturonate-sp_porin |
PANTHERi | PTHR38105, PTHR38105, 1 hit |
Pfami | View protein in Pfam PF06178, KdgM, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P76773-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKINAIILL SSLTSASVFA GAYVENREAY NLASDQGEVM LRVGYNFDMG
60 70 80 90 100
AGIMLTNTYN FQREDELKHG YNEIEGWYPL FKPTDKLTIQ PGGLINDKSI
110 120 130 140 150
GSGGAVYLDV NYKFVPWFNL TVRNRYNHNN YSSTDLSGEL DNNDTYEIGT
160 170 180 190 200
YWNFKITDKF SYTFEPHYFM RVNDFNSSNG KDHHWEITNT FRYRINEHWL
210 220 230
PYFELRWLDR NVEPYHREQN QIRIGTKYFF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L19201 Genomic DNA Translation: AAB03009.1 Frameshift. U00096 Genomic DNA Translation: AAC76872.1 AP009048 Genomic DNA Translation: BAE77434.1 |
PIRi | F65192 |
RefSeqi | NP_418311.1, NC_000913.3 WP_000723465.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC76872; AAC76872; b3875 BAE77434; BAE77434; BAE77434 |
GeneIDi | 948366 |
KEGGi | ecj:JW3846 eco:b3875 |
PATRICi | fig|1411691.4.peg.2836 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L19201 Genomic DNA Translation: AAB03009.1 Frameshift. U00096 Genomic DNA Translation: AAC76872.1 AP009048 Genomic DNA Translation: BAE77434.1 |
PIRi | F65192 |
RefSeqi | NP_418311.1, NC_000913.3 WP_000723465.1, NZ_LN832404.1 |
3D structure databases
SMRi | P76773 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4262635, 212 interactors |
IntActi | P76773, 21 interactors |
STRINGi | 511145.b3875 |
Protein family/group databases
TCDBi | 1.B.35.2.2, the oligogalacturonate-specific porin (kdgm) family |
Proteomic databases
PaxDbi | P76773 |
PRIDEi | P76773 |
Genome annotation databases
EnsemblBacteriai | AAC76872; AAC76872; b3875 BAE77434; BAE77434; BAE77434 |
GeneIDi | 948366 |
KEGGi | ecj:JW3846 eco:b3875 |
PATRICi | fig|1411691.4.peg.2836 |
Organism-specific databases
EchoBASEi | EB3156 |
Phylogenomic databases
eggNOGi | COG1452, Bacteria |
HOGENOMi | CLU_103714_0_0_6 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7814-MONOMER |
Miscellaneous databases
PROi | PR:P76773 |
Family and domain databases
InterProi | View protein in InterPro IPR009331, Oligogalacturonate-sp_porin |
PANTHERi | PTHR38105, PTHR38105, 1 hit |
Pfami | View protein in Pfam PF06178, KdgM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | OMPL_ECOLI | |
Accessioni | P76773Primary (citable) accession number: P76773 Secondary accession number(s): Q2M8H2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | February 1, 1997 | |
Last modified: | April 7, 2021 | |
This is version 136 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families