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Protein

Protein CsiD

Gene

csiD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in the control of utilization of gamma-aminobutyric acid.1 Publication

Cofactori

Fe cation1 PublicationNote: Binds 1 Fe cation per subunit.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi160Iron1 Publication1
Metal bindingi162Iron1 Publication1
Metal bindingi292Iron1 Publication1

GO - Molecular functioni

  • identical protein binding Source: EcoCyc
  • iron ion binding Source: EcoCyc

GO - Biological processi

  • protein homotetramerization Source: EcoCyc
  • response to carbon starvation Source: EcoCyc

Keywordsi

LigandIron, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7394-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein CsiDCurated
Gene namesi
Name:csiD1 Publication
Synonyms:gab1 Publication, ygaT
Ordered Locus Names:b2659, JW5427
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13523 csiD

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002181771 – 325Protein CsiDAdd BLAST325

Proteomic databases

EPDiP76621
PaxDbiP76621
PRIDEiP76621

Expressioni

Inductioni

Expression is induced by RpoS during carbon starvation and at stationary phase. Is also regulated by cAMP-CRP and Lrp, which play the roles of a nearly essential activator and of a positive modulator, respectively. Repressed by CsiR.2 Publications

Interactioni

Subunit structurei

Homotetramer.1 Publication

GO - Molecular functioni

  • identical protein binding Source: EcoCyc

Protein-protein interaction databases

BioGridi4259208, 8 interactors
STRINGi316385.ECDH10B_2826

Structurei

Secondary structure

1325
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi19 – 25Combined sources7
Beta strandi32 – 37Combined sources6
Helixi39 – 49Combined sources11
Helixi54 – 59Combined sources6
Helixi62 – 74Combined sources13
Turni75 – 77Combined sources3
Helixi79 – 88Combined sources10
Beta strandi94 – 99Combined sources6
Helixi105 – 107Combined sources3
Helixi108 – 122Combined sources15
Beta strandi123 – 125Combined sources3
Turni129 – 131Combined sources3
Beta strandi132 – 140Combined sources9
Beta strandi157 – 160Combined sources4
Beta strandi166 – 168Combined sources3
Beta strandi172 – 182Combined sources11
Beta strandi188 – 192Combined sources5
Helixi193 – 195Combined sources3
Helixi199 – 203Combined sources5
Helixi206 – 209Combined sources4
Beta strandi212 – 214Combined sources3
Beta strandi226 – 228Combined sources3
Beta strandi230 – 233Combined sources4
Beta strandi239 – 241Combined sources3
Turni245 – 247Combined sources3
Helixi253 – 267Combined sources15
Beta strandi273 – 275Combined sources3
Beta strandi282 – 286Combined sources5
Turni287 – 289Combined sources3
Beta strandi290 – 294Combined sources5
Beta strandi304 – 314Combined sources11

3D structure databases

ProteinModelPortaliP76621
SMRiP76621
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP76621

Family & Domainsi

Sequence similaritiesi

Belongs to the CsiD family.Curated

Phylogenomic databases

eggNOGiENOG4105EK3 Bacteria
ENOG410XQW4 LUCA
HOGENOMiHOG000224333
KOiK15737
OMAiHNDGTFV

Family and domain databases

HAMAPiMF_01083 CsiD, 1 hit
InterProiView protein in InterPro
IPR015038 Uncharacterised_CsiD
PfamiView protein in Pfam
PF08943 CsiD, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD135861 DUF_CsiD, 1 hit

Sequencei

Sequence statusi: Complete.

P76621-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNALTAVQNN AVDSGQDYSG FTLTPSAQSP RLLELTFTEQ TTKQFLEQVA
60 70 80 90 100
EWPVQALEYK SFLRFRVAKI LDDLCANQLQ PLLLKTLLNR AEGALLINAV
110 120 130 140 150
GVDDVKQADE MVKLATAVAH LIGRSNFDAM SGQYYARFVV KNVDNSDSYL
160 170 180 190 200
RQPHRVMELH NDGTYVEEIT DYVLMMKIDE QNMQGGNSLL LHLDDWEHLD
210 220 230 240 250
NYFRHPLARR PMRFAAPPSK NVSKDVFHPV FDVDQQGRPV MRYIDQFVQP
260 270 280 290 300
KDFEEGVWLS ELSDAIETSK GILSVPVPVG KFLLINNLFW LHGRDRFTPH
310 320
PDLRRELMRQ RGYFAYASNH YQTHQ
Length:325
Mass (Da):37,360
Last modified:June 1, 2001 - v2
Checksum:iAF403B3029E0B7F4
GO

Sequence cautioni

The sequence AAD10865 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti152 – 153QP → HA in AAD10865 (Ref. 1) Curated2
Sequence conflicti212 – 213MR → IA in AAD10865 (Ref. 1) Curated2
Sequence conflicti310 – 311QR → HG in AAD10865 (Ref. 1) Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68243 Genomic DNA Translation: AAD10865.1 Different initiation.
U00096 Genomic DNA Translation: AAC75706.2
AP009048 Genomic DNA Translation: BAE76779.1
PIRiD65045
RefSeqiNP_417145.4, NC_000913.3
WP_000993126.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75706; AAC75706; b2659
BAE76779; BAE76779; BAE76779
GeneIDi948076
KEGGiecj:JW5427
eco:b2659
PATRICifig|1411691.4.peg.4082

Similar proteinsi

Entry informationi

Entry nameiCSID_ECOLI
AccessioniPrimary (citable) accession number: P76621
Secondary accession number(s): Q2MAC7, Q9ZAZ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: June 1, 2001
Last modified: July 18, 2018
This is version 123 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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