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UniProtKB - P76585 (YPHG_ECOLI)

Entry version 137 (25 May 2022)
Sequence version 2 (04 Dec 2007)
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Protein

Uncharacterized protein YphG

Gene

yphG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

  • cell division Source: GO_Central
Complete GO annotation on QuickGO ...

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:G7343-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein YphG
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yphG
Ordered Locus Names:b2549, JW5405
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001692601 – 1093Uncharacterized protein YphGAdd BLAST1093

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P76585

PRoteomics IDEntifications database

More...PRIDEi		P76585

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4261313, 6 interactors

Database of interacting proteins

More...DIPi		DIP-12832N

STRING: functional protein association networks

More...STRINGi		511145.b2549

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		P76585

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG0457, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_010402_0_0_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P76585

Identification of Orthologs from Complete Genome Data

More...OMAi		NAVFDHG

Database for complete collections of gene phylogenies

More...PhylomeDBi		P76585

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 2 hits
2.70.98.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR033396, DUF5107
IPR014718, GH-type_carb-bd
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat

Pfam protein domain database

More...Pfami		View protein in Pfam
PF17128, DUF5107, 1 hit
PF13181, TPR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00028, TPR, 5 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48452, SSF48452, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50293, TPR_REGION, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P76585-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTPVKVWQER VEIPTYETGP QDIHPMFLEN RVYQGSSGAV YPYGVTDTLS 
        60         70         80         90        100
EQKTLKSWQA VWLENDYIKV MILPELGGRV HRAWDKVKQR DFVYHNEVIK 
       110        120        130        140        150
PALVGLLGPW ISGGIEFNWP QHHRPTTFMP VDFTLEAHED GAQTVWVGET 
       160        170        180        190        200
EPMHGLQVMT GFTLRPDRAA LEIASRVYNG NATPRHFLWW ANPAVKGGEG 
       210        220        230        240        250
HQSVFPPDVT AVFDHGKRAV SAFPIATGTY YKVDYSAGVD ISRYKNVPVP 
       260        270        280        290        300
TSYMAEKSQY DFVGAWCHDE DGGLLHVANH HIAPGKKQWS WGHSEFGQAW 
       310        320        330        340        350
DKSLTDNNGP YIELMTGIFA DNQPDFTWLD AYEEKRFEQY FLPYHSLGMV 
       360        370        380        390        400
QNASRDAVIK LQRSKRGIEW GLYAISPLNG YRLAIREIGK CNALLDDAVA 
       410        420        430        440        450
LMPATAIQGV LHGINPERLT IELSDADGNI VLSYQEHQPQ ALPLPDVAKA 
       460        470        480        490        500
PLAAQDITST DEAWFIGQHL EQYHHASRSP FDYYLRGVAL DPLDYRCNLA 
       510        520        530        540        550
LAMLEYNRAD FPQAVAYATQ ALKRAHALNK NPQCGQASLI RASAYERQGQ 
       560        570        580        590        600
YQQAEEDFWR AVWSGNSKAG GYYGLARLAA RNGNFDAGLD FCQQSLRACP 
       610        620        630        640        650
TNQEVLCLHN LLLVLSGRQD NARVQREKLL RDYPLNATLW WLNWFDGRSE 
       660        670        680        690        700
SALAQWRGLC QGRDVNALMT AGQLINWGMP TLAAEMLNAL DCQRTLPLYL 
       710        720        730        740        750
QASLLPKAER GELVAKAIDV FPQFVRFPNT LEEVAALESI EECWFARHLL 
       760        770        780        790        800
ACFYYNKRSY NKAIAFWQRC VEMSPEFADG WRGLAIHAWN KQHDYELAAR 
       810        820        830        840        850
YLDNAYQLAP QDARLLFERD LLDKLSGATP EKRLARLENN LEIALKRDDM 
       860        870        880        890        900
TAELLNLWHL TGQADKAADI LATRKFHPWE GGEGKVTSQF ILNQLLRAWQ 
       910        920        930        940        950
HLDARQPQQA CELLHAALHY PENLSEGRLP GQTDNDIWFW QAICANAQGD 
       960        970        980        990       1000
ETEATRCLRL AATGDRTINI HSYYNDQPVD YLFWQGMALR LLGEQQTAQQ 
      1010       1020       1030       1040       1050
LFSEMKQWAQ EMAKTSIEAD FFAVSQPDLL SLYGDLQQQH KEKCLMVAML 
      1060       1070       1080       1090 
ASAGLGEVAQ YESARAELTA INPAWPKAAL FTTVMPFIFN RVH
Length:1,093
Mass (Da):123,832
Last modified:December 4, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6CD428F509131A0F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75602.2
AP009048 Genomic DNA Translation: BAE76731.1

Protein sequence database of the Protein Information Resource

More...PIRi		D65032

NCBI Reference Sequences

More...RefSeqi		NP_417044.4, NC_000913.3
WP_001333903.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC75602; AAC75602; b2549
BAE76731; BAE76731; BAE76731

Database of genes from NCBI RefSeq genomes

More...GeneIDi		947021

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW5405
eco:b2549

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|511145.12.peg.2650

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75602.2
AP009048 Genomic DNA Translation: BAE76731.1
PIRiD65032
RefSeqiNP_417044.4, NC_000913.3
WP_001333903.1, NZ_LN832404.1

3D structure databases

AlphaFoldDBiP76585
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

BioGRIDi4261313, 6 interactors
DIPiDIP-12832N
STRINGi511145.b2549

Proteomic databases

PaxDbiP76585
PRIDEiP76585

Genome annotation databases

EnsemblBacteriaiAAC75602; AAC75602; b2549
BAE76731; BAE76731; BAE76731
GeneIDi947021
KEGGiecj:JW5405
eco:b2549
PATRICifig|511145.12.peg.2650

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB3241

Phylogenomic databases

eggNOGiCOG0457, Bacteria
HOGENOMiCLU_010402_0_0_6
InParanoidiP76585
OMAiNAVFDHG
PhylomeDBiP76585

Enzyme and pathway databases

BioCyciEcoCyc:G7343-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:P76585

Family and domain databases

Gene3Di1.25.40.10, 2 hits
2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR033396, DUF5107
IPR014718, GH-type_carb-bd
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
PfamiView protein in Pfam
PF17128, DUF5107, 1 hit
PF13181, TPR_8, 1 hit
SMARTiView protein in SMART
SM00028, TPR, 5 hits
SUPFAMiSSF48452, SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS50293, TPR_REGION, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYPHG_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P76585
Secondary accession number(s): Q2MAH5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: December 4, 2007
Last modified: May 25, 2022
This is version 137 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome
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