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Entry version 132 (07 Oct 2020)
Sequence version 2 (04 Dec 2007)
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Protein

Uncharacterized protein YphG

Gene

yphG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • cell division Source: GO_Central

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:G7343-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein YphG
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yphG
Ordered Locus Names:b2549, JW5405
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001692601 – 1093Uncharacterized protein YphGAdd BLAST1093

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P76585

PRoteomics IDEntifications database

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PRIDEi
P76585

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
4261313, 6 interactors

Database of interacting proteins

More...
DIPi
DIP-12832N

STRING: functional protein association networks

More...
STRINGi
511145.b2549

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P76585

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0457, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010402_0_0_6

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P76585

Database for complete collections of gene phylogenies

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PhylomeDBi
P76585

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033396, DUF5107
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17128, DUF5107, 1 hit
PF13181, TPR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028, TPR, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452, SSF48452, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50293, TPR_REGION, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P76585-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTPVKVWQER VEIPTYETGP QDIHPMFLEN RVYQGSSGAV YPYGVTDTLS
60 70 80 90 100
EQKTLKSWQA VWLENDYIKV MILPELGGRV HRAWDKVKQR DFVYHNEVIK
110 120 130 140 150
PALVGLLGPW ISGGIEFNWP QHHRPTTFMP VDFTLEAHED GAQTVWVGET
160 170 180 190 200
EPMHGLQVMT GFTLRPDRAA LEIASRVYNG NATPRHFLWW ANPAVKGGEG
210 220 230 240 250
HQSVFPPDVT AVFDHGKRAV SAFPIATGTY YKVDYSAGVD ISRYKNVPVP
260 270 280 290 300
TSYMAEKSQY DFVGAWCHDE DGGLLHVANH HIAPGKKQWS WGHSEFGQAW
310 320 330 340 350
DKSLTDNNGP YIELMTGIFA DNQPDFTWLD AYEEKRFEQY FLPYHSLGMV
360 370 380 390 400
QNASRDAVIK LQRSKRGIEW GLYAISPLNG YRLAIREIGK CNALLDDAVA
410 420 430 440 450
LMPATAIQGV LHGINPERLT IELSDADGNI VLSYQEHQPQ ALPLPDVAKA
460 470 480 490 500
PLAAQDITST DEAWFIGQHL EQYHHASRSP FDYYLRGVAL DPLDYRCNLA
510 520 530 540 550
LAMLEYNRAD FPQAVAYATQ ALKRAHALNK NPQCGQASLI RASAYERQGQ
560 570 580 590 600
YQQAEEDFWR AVWSGNSKAG GYYGLARLAA RNGNFDAGLD FCQQSLRACP
610 620 630 640 650
TNQEVLCLHN LLLVLSGRQD NARVQREKLL RDYPLNATLW WLNWFDGRSE
660 670 680 690 700
SALAQWRGLC QGRDVNALMT AGQLINWGMP TLAAEMLNAL DCQRTLPLYL
710 720 730 740 750
QASLLPKAER GELVAKAIDV FPQFVRFPNT LEEVAALESI EECWFARHLL
760 770 780 790 800
ACFYYNKRSY NKAIAFWQRC VEMSPEFADG WRGLAIHAWN KQHDYELAAR
810 820 830 840 850
YLDNAYQLAP QDARLLFERD LLDKLSGATP EKRLARLENN LEIALKRDDM
860 870 880 890 900
TAELLNLWHL TGQADKAADI LATRKFHPWE GGEGKVTSQF ILNQLLRAWQ
910 920 930 940 950
HLDARQPQQA CELLHAALHY PENLSEGRLP GQTDNDIWFW QAICANAQGD
960 970 980 990 1000
ETEATRCLRL AATGDRTINI HSYYNDQPVD YLFWQGMALR LLGEQQTAQQ
1010 1020 1030 1040 1050
LFSEMKQWAQ EMAKTSIEAD FFAVSQPDLL SLYGDLQQQH KEKCLMVAML
1060 1070 1080 1090
ASAGLGEVAQ YESARAELTA INPAWPKAAL FTTVMPFIFN RVH
Length:1,093
Mass (Da):123,832
Last modified:December 4, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6CD428F509131A0F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75602.2
AP009048 Genomic DNA Translation: BAE76731.1

Protein sequence database of the Protein Information Resource

More...
PIRi
D65032

NCBI Reference Sequences

More...
RefSeqi
NP_417044.4, NC_000913.3
WP_001333903.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC75602; AAC75602; b2549
BAE76731; BAE76731; BAE76731

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
947021

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW5405
eco:b2549

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|511145.12.peg.2650

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75602.2
AP009048 Genomic DNA Translation: BAE76731.1
PIRiD65032
RefSeqiNP_417044.4, NC_000913.3
WP_001333903.1, NZ_LN832404.1

3D structure databases

SMRiP76585
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4261313, 6 interactors
DIPiDIP-12832N
STRINGi511145.b2549

Proteomic databases

PaxDbiP76585
PRIDEiP76585

Genome annotation databases

EnsemblBacteriaiAAC75602; AAC75602; b2549
BAE76731; BAE76731; BAE76731
GeneIDi947021
KEGGiecj:JW5405
eco:b2549
PATRICifig|511145.12.peg.2650

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB3241

Phylogenomic databases

eggNOGiCOG0457, Bacteria
HOGENOMiCLU_010402_0_0_6
InParanoidiP76585
PhylomeDBiP76585

Enzyme and pathway databases

BioCyciEcoCyc:G7343-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P76585

Family and domain databases

Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR033396, DUF5107
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
PfamiView protein in Pfam
PF17128, DUF5107, 1 hit
PF13181, TPR_8, 1 hit
SMARTiView protein in SMART
SM00028, TPR, 5 hits
SUPFAMiSSF48452, SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS50293, TPR_REGION, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYPHG_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P76585
Secondary accession number(s): Q2MAH5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: December 4, 2007
Last modified: October 7, 2020
This is version 132 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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