UniProtKB - P76470 (RHMT_ECOLI)
Protein
Inner membrane transport protein RhmT
Gene
rhmT
Organism
Escherichia coli (strain K12)
Status
Functioni
Miscellaneous
Part of the rhmRDTA operon involved in L-rhamnonate utilization.
GO - Molecular functioni
- transmembrane transporter activity Source: GO_Central
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:B2246-MONOMER |
Protein family/group databases
TCDBi | 2.A.1.14.35, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Inner membrane transport protein RhmT |
Gene namesi | Name:rhmT Synonyms:yfaV Ordered Locus Names:b2246, JW2240 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 16 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 17 – 37 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 38 – 54 | PeriplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 55 – 75 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 76 – 81 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 82 – 102 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 103 – 143 | PeriplasmicSequence analysisAdd BLAST | 41 | |
Transmembranei | 144 – 164 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 165 – 174 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 175 – 195 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 196 – 242 | PeriplasmicSequence analysisAdd BLAST | 47 | |
Transmembranei | 243 – 263 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 264 – 274 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 275 – 295 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 296 – 324 | PeriplasmicSequence analysisAdd BLAST | 29 | |
Transmembranei | 325 – 345 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 346 – 361 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 362 – 382 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 383 – 394 | PeriplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 395 – 415 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 416 – 429 | CytoplasmicSequence analysisAdd BLAST | 14 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- intrinsic component of membrane Source: GO_Central
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000121390 | 1 – 429 | Inner membrane transport protein RhmTAdd BLAST | 429 |
Proteomic databases
PaxDbi | P76470 |
PRIDEi | P76470 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260489, 115 interactors |
STRINGi | 511145.b2246 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2271, Bacteria |
HOGENOMi | CLU_001265_0_0_6 |
InParanoidi | P76470 |
PhylomeDBi | P76470 |
Family and domain databases
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
P76470-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTALLDAVV KKNRVRLIPF MLALYVLAFL DRSNIGFAKQ TYQIDTGLSN
60 70 80 90 100
EAYALGAGIF FVVYAFLGVP ANLLMRKLGA RTWIGTTTLL WGFLSAAMAW
110 120 130 140 150
ADTEAKFLIV RTLLRAAEAG FFPGMIYLTS QWFPQRNRAS IMGLFYMGAP
160 170 180 190 200
LALTLGSPLS GALLEMHGFM GHPGWFWMFV IEGLLAVGAG VFTFFWLDDT
210 220 230 240 250
PEQARFLSKQ EKTLLINQLA SEEQQKVTSR LSDALRNGRV WQLAIIYLTI
260 270 280 290 300
QVAVYGLIFF LPTQVAALLG TKVGFTASVV TAIPWVAALF GTWLIPRYSD
310 320 330 340 350
KTGERRNVAA LTLLAAGIGI GLSGLLSPVM AIVALCVAAI GFIAVQPVFW
360 370 380 390 400
TMPTQLLSGT ALAAGIGFVN LFGAVGGFIA PILRVKAETL FASDAAGLLT
410 420
LAAVAVIGSL IIFTLRVNRT VAQTDVAHH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75306.2 AP009048 Genomic DNA Translation: BAA16070.1 |
PIRi | D64995 |
RefSeqi | NP_416749.4, NC_000913.3 WP_000100890.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC75306; AAC75306; b2246 BAA16070; BAA16070; BAA16070 |
GeneIDi | 945796 |
KEGGi | ecj:JW2240 eco:b2246 |
PATRICi | fig|511145.12.peg.2337 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75306.2 AP009048 Genomic DNA Translation: BAA16070.1 |
PIRi | D64995 |
RefSeqi | NP_416749.4, NC_000913.3 WP_000100890.1, NZ_LN832404.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4260489, 115 interactors |
STRINGi | 511145.b2246 |
Protein family/group databases
TCDBi | 2.A.1.14.35, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | P76470 |
PRIDEi | P76470 |
Genome annotation databases
EnsemblBacteriai | AAC75306; AAC75306; b2246 BAA16070; BAA16070; BAA16070 |
GeneIDi | 945796 |
KEGGi | ecj:JW2240 eco:b2246 |
PATRICi | fig|511145.12.peg.2337 |
Organism-specific databases
EchoBASEi | EB3837 |
Phylogenomic databases
eggNOGi | COG2271, Bacteria |
HOGENOMi | CLU_001265_0_0_6 |
InParanoidi | P76470 |
PhylomeDBi | P76470 |
Enzyme and pathway databases
BioCyci | EcoCyc:B2246-MONOMER |
Miscellaneous databases
PROi | PR:P76470 |
Family and domain databases
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RHMT_ECOLI | |
Accessioni | P76470Primary (citable) accession number: P76470 Secondary accession number(s): P76930 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 15, 1998 |
Last sequence update: | December 15, 1998 | |
Last modified: | October 7, 2020 | |
This is version 139 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families