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UniProtKB - P76268 (KDGR_ECOLI)
Protein
Transcriptional regulator KdgR
Gene
kdgR
Organism
Escherichia coli (strain K12)
Status
Functioni
Transcriptional regulator of the kdgK gene for the kdg kinase and the kdgT gene for the kdg permease.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 34 – 53 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- DNA binding Source: GO_Central
- DNA-binding transcription factor activity Source: EcoCyc
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: EcoCyc
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
BioCyci | EcoCyc:G7003-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Transcriptional regulator KdgR |
Gene namesi | Name:kdgR Synonyms:yebP Ordered Locus Names:b1827, JW1816 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000201760 | 1 – 263 | Transcriptional regulator KdgRAdd BLAST | 263 |
Proteomic databases
jPOSTi | P76268 |
PaxDbi | P76268 |
PRIDEi | P76268 |
Interactioni
Binary interactionsi
P76268
With | #Exp. | IntAct |
---|---|---|
yebV [P64503] | 3 | EBI-1123676,EBI-9126792 |
Protein-protein interaction databases
BioGRIDi | 4261734, 17 interactors 850489, 1 interactor |
DIPi | DIP-10057N |
IntActi | P76268, 4 interactors |
STRINGi | 511145.b1827 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P76268 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P76268 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 13 – 74 | HTH iclR-typePROSITE-ProRule annotationAdd BLAST | 62 | |
Domaini | 89 – 258 | IclR-EDPROSITE-ProRule annotationAdd BLAST | 170 |
Phylogenomic databases
eggNOGi | COG1414, Bacteria |
HOGENOMi | CLU_062618_6_0_6 |
InParanoidi | P76268 |
PhylomeDBi | P76268 |
Family and domain databases
CDDi | cd00090, HTH_ARSR, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 3.30.450.40, 1 hit |
InterProi | View protein in InterPro IPR011991, ArsR-like_HTH IPR029016, GAF-like_dom_sf IPR014757, Tscrpt_reg_IclR_C IPR005471, Tscrpt_reg_IclR_N IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF09339, HTH_IclR, 1 hit PF01614, IclR, 1 hit |
SMARTi | View protein in SMART SM00346, HTH_ICLR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS51077, HTH_ICLR, 1 hit PS51078, ICLR_ED, 1 hit |
i Sequence
Sequence statusi: Complete.
P76268-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MANADLDKQP DSVSSVLKVF GILQALGEER EIGITELSQR VMMSKSTVYR
60 70 80 90 100
FLQTMKTLGY VAQEGESEKY SLTLKLFELG ARALQNVDLI RSADIQMREL
110 120 130 140 150
SRLTKETIHL GALDEDSIVY IHKIDSMYNL RMYSRIGRRN PLYSTAIGKV
160 170 180 190 200
LLAWRDRDEV KQILEGVEYK RSTERTITST EALLPVLDQV REQGYGEDNE
210 220 230 240 250
EQEEGLRCIA VPVFDRFGVV IAGLSISFPT LRFSEERLQE YVAMLHTAAR
260
KISAQMGYHD YPF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74897.1 AP009048 Genomic DNA Translation: BAA15635.1 |
PIRi | C64944 |
RefSeqi | NP_416341.1, NC_000913.3 WP_001262203.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC74897; AAC74897; b1827 BAA15635; BAA15635; BAA15635 |
GeneIDi | 946129 |
KEGGi | ecj:JW1816 eco:b1827 |
PATRICi | fig|1411691.4.peg.423 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74897.1 AP009048 Genomic DNA Translation: BAA15635.1 |
PIRi | C64944 |
RefSeqi | NP_416341.1, NC_000913.3 WP_001262203.1, NZ_LN832404.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1YSP | X-ray | 1.80 | A | 88-263 | [»] | |
SMRi | P76268 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 4261734, 17 interactors 850489, 1 interactor |
DIPi | DIP-10057N |
IntActi | P76268, 4 interactors |
STRINGi | 511145.b1827 |
Proteomic databases
jPOSTi | P76268 |
PaxDbi | P76268 |
PRIDEi | P76268 |
Genome annotation databases
EnsemblBacteriai | AAC74897; AAC74897; b1827 BAA15635; BAA15635; BAA15635 |
GeneIDi | 946129 |
KEGGi | ecj:JW1816 eco:b1827 |
PATRICi | fig|1411691.4.peg.423 |
Organism-specific databases
EchoBASEi | EB3772 |
Phylogenomic databases
eggNOGi | COG1414, Bacteria |
HOGENOMi | CLU_062618_6_0_6 |
InParanoidi | P76268 |
PhylomeDBi | P76268 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7003-MONOMER |
Miscellaneous databases
EvolutionaryTracei | P76268 |
PROi | PR:P76268 |
Family and domain databases
CDDi | cd00090, HTH_ARSR, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 3.30.450.40, 1 hit |
InterProi | View protein in InterPro IPR011991, ArsR-like_HTH IPR029016, GAF-like_dom_sf IPR014757, Tscrpt_reg_IclR_C IPR005471, Tscrpt_reg_IclR_N IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF09339, HTH_IclR, 1 hit PF01614, IclR, 1 hit |
SMARTi | View protein in SMART SM00346, HTH_ICLR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS51077, HTH_ICLR, 1 hit PS51078, ICLR_ED, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | KDGR_ECOLI | |
Accessioni | P76268Primary (citable) accession number: P76268 Secondary accession number(s): O07975 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | February 1, 1997 | |
Last modified: | June 2, 2021 | |
This is version 159 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references