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UniProtKB - P76192 (YDHV_ECOLI)

Entry version 127 (10 Feb 2021)
Sequence version 1 (01 Feb 1997)
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Protein

Uncharacterized oxidoreductase YdhV

Gene

ydhV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi307Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi310Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi314Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi558Iron-sulfur (4Fe-4S)By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:G6901-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized oxidoreductase YdhV (EC:1.-.-.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ydhV
Ordered Locus Names:b1673, JW5272
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001689801 – 700Uncharacterized oxidoreductase YdhVAdd BLAST700

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P76192

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P76192

PRoteomics IDEntifications database

More...PRIDEi		P76192

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by the oxygen-responsive transcription factor FNR under anaerobic conditions. Repressed in the presence of nitrate or nitrite via the two-component systems NarXL and NarPQ, respectively.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4260274, 6 interactors

STRING: functional protein association networks

More...STRINGi		511145.b1673

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the AOR/FOR family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG2414, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_020364_0_0_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P76192

Database for complete collections of gene phylogenies

More...PhylomeDBi		P76192

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.569.10, 1 hit
1.10.599.10, 1 hit
3.60.9.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013984, Ald_Fedxn_OxRdtase_dom2
IPR013985, Ald_Fedxn_OxRdtase_dom3
IPR013983, Ald_Fedxn_OxRdtase_N
IPR036503, Ald_Fedxn_OxRdtase_N_sf
IPR001203, OxRdtase_Ald_Fedxn_C
IPR036021, Tungsten_al_ferr_oxy-like_C

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01314, AFOR_C, 1 hit
PF02730, AFOR_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00790, AFOR_N, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48310, SSF48310, 1 hit
SSF56228, SSF56228, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P76192-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANGWTGNIL RVNLTTGNIT LEDSSKFKSF VGGMGFGYKI MYDEVPPGTK 
        60         70         80         90        100
PFDEANKLVF ATGPLTGSGA PCSSRVNITS LSTFTKGNLV VDAHMGGFFA 
       110        120        130        140        150
AQMKFAGYDV IIIEGKAKSP VWLKIKDDKV SLEKADFLWG KGTRATTEEI 
       160        170        180        190        200
CRLTSPETCV AAIGQAGENL VPLSGMLNSR NHSGGAGTGA IMGSKNLKAI 
       210        220        230        240        250
AVEGTKGVNI ADRQEMKRLN DYMMTELIGA NNNHVVPSTP QSWAEYSDPK 
       260        270        280        290        300
SRWTARKGLF WGAAEGGPIE TGEIPPGNQN TVGFRTYKSV FDLGPAAEKY 
       310        320        330        340        350
TVKMSGCHSC PIRCMTQMNI PRVKEFGVPS TGGNTCVANF VHTTIFPNGP 
       360        370        380        390        400
KDFEDKDDGR VIGNLVGLNL FDDYGLWCNY GQLHRDFTYC YSKGVFKRVL 
       410        420        430        440        450
PAEEYAEIRW DQLEAGDVNF IKDFYYRLAH RVGELSHLAD GSYAIAERWN 
       460        470        480        490        500
LGEEYWGYAK NKLWSPFGYP VHHANEASAQ VGSIVNCMFN RDCMTHTHIN 
       510        520        530        540        550
FIGSGLPLKL QREVAKELFG SEDAYDETKN YTPINDAKIK YAKWSLLRVC 
       560        570        580        590        600
LHNAVTLCNW VWPMTVSPLK SRNYRGDLAL EAKFFKAITG EEMTQEKLDL 
       610        620        630        640        650
AAERIFTLHR AYTVKLMQTK DMRNEHDLIC SWVFDKDPQI PVFTEGTDKM 
       660        670        680        690        700
DRDDMHASLT MFYKEMGWDP QLGCPTRETL QRLGLEDIAA DLAAHNLLPA
Length:700
Mass (Da):77,877
Last modified:February 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA8C1A670C02D804
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB47949 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U68703 Genomic DNA Translation: AAB47949.1 Different initiation.
U00096 Genomic DNA Translation: AAC74743.1
AP009048 Genomic DNA Translation: BAE76498.1

Protein sequence database of the Protein Information Resource

More...PIRi		A64925

NCBI Reference Sequences

More...RefSeqi		NP_416188.1, NC_000913.3
WP_001273527.1, NZ_SSZK01000001.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC74743; AAC74743; b1673
BAE76498; BAE76498; BAE76498

Database of genes from NCBI RefSeq genomes

More...GeneIDi		57731069
948756

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW5272
eco:b1673

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.586

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68703 Genomic DNA Translation: AAB47949.1 Different initiation.
U00096 Genomic DNA Translation: AAC74743.1
AP009048 Genomic DNA Translation: BAE76498.1
PIRiA64925
RefSeqiNP_416188.1, NC_000913.3
WP_001273527.1, NZ_SSZK01000001.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi4260274, 6 interactors
STRINGi511145.b1673

Proteomic databases

jPOSTiP76192
PaxDbiP76192
PRIDEiP76192

Genome annotation databases

EnsemblBacteriaiAAC74743; AAC74743; b1673
BAE76498; BAE76498; BAE76498
GeneIDi57731069
948756
KEGGiecj:JW5272
eco:b1673
PATRICifig|1411691.4.peg.586

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB3714

Phylogenomic databases

eggNOGiCOG2414, Bacteria
HOGENOMiCLU_020364_0_0_6
InParanoidiP76192
PhylomeDBiP76192

Enzyme and pathway databases

BioCyciEcoCyc:G6901-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:P76192

Family and domain databases

Gene3Di1.10.569.10, 1 hit
1.10.599.10, 1 hit
3.60.9.10, 1 hit
InterProiView protein in InterPro
IPR013984, Ald_Fedxn_OxRdtase_dom2
IPR013985, Ald_Fedxn_OxRdtase_dom3
IPR013983, Ald_Fedxn_OxRdtase_N
IPR036503, Ald_Fedxn_OxRdtase_N_sf
IPR001203, OxRdtase_Ald_Fedxn_C
IPR036021, Tungsten_al_ferr_oxy-like_C
PfamiView protein in Pfam
PF01314, AFOR_C, 1 hit
PF02730, AFOR_N, 1 hit
SMARTiView protein in SMART
SM00790, AFOR_N, 1 hit
SUPFAMiSSF48310, SSF48310, 1 hit
SSF56228, SSF56228, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYDHV_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P76192
Secondary accession number(s): P71277, Q2MB58
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: February 10, 2021
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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