UniProtKB - P76192 (YDHV_ECOLI)
Protein
Uncharacterized oxidoreductase YdhV
Gene
ydhV
Organism
Escherichia coli (strain K12)
Status
Functioni
Cofactori
Protein has several cofactor binding sites:- [4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster per subunit.By similarity
- Mo-molybdopterinBy similarity, tungstopterinBy similarityNote: Binds 1 Mo-molybdopterin (Mo-MPT) or 1 tungstopterin cofactor per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 307 | Iron-sulfur (4Fe-4S)By similarity | 1 | |
Metal bindingi | 310 | Iron-sulfur (4Fe-4S)By similarity | 1 | |
Metal bindingi | 314 | Iron-sulfur (4Fe-4S)By similarity | 1 | |
Metal bindingi | 558 | Iron-sulfur (4Fe-4S)By similarity | 1 |
GO - Molecular functioni
- 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
- electron transfer activity Source: InterPro
- iron-sulfur cluster binding Source: EcoCyc
- metal ion binding Source: UniProtKB-KW
- molybdopterin cofactor binding Source: EcoCyc
- oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor Source: InterPro
Keywordsi
Molecular function | Oxidoreductase |
Ligand | 4Fe-4S, Iron, Iron-sulfur, Metal-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:G6901-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ydhV Ordered Locus Names:b1673, JW5272 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000168980 | 1 – 700 | Uncharacterized oxidoreductase YdhVAdd BLAST | 700 |
Proteomic databases
jPOSTi | P76192 |
PaxDbi | P76192 |
PRIDEi | P76192 |
Expressioni
Inductioni
Up-regulated by the oxygen-responsive transcription factor FNR under anaerobic conditions. Repressed in the presence of nitrate or nitrite via the two-component systems NarXL and NarPQ, respectively.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260274, 6 interactors |
STRINGi | 511145.b1673 |
Family & Domainsi
Sequence similaritiesi
Belongs to the AOR/FOR family.Curated
Phylogenomic databases
eggNOGi | COG2414, Bacteria |
HOGENOMi | CLU_020364_0_0_6 |
InParanoidi | P76192 |
PhylomeDBi | P76192 |
Family and domain databases
Gene3Di | 1.10.569.10, 1 hit 1.10.599.10, 1 hit 3.60.9.10, 1 hit |
InterProi | View protein in InterPro IPR013984, Ald_Fedxn_OxRdtase_dom2 IPR013985, Ald_Fedxn_OxRdtase_dom3 IPR013983, Ald_Fedxn_OxRdtase_N IPR036503, Ald_Fedxn_OxRdtase_N_sf IPR001203, OxRdtase_Ald_Fedxn_C IPR036021, Tungsten_al_ferr_oxy-like_C |
Pfami | View protein in Pfam PF01314, AFOR_C, 1 hit PF02730, AFOR_N, 1 hit |
SMARTi | View protein in SMART SM00790, AFOR_N, 1 hit |
SUPFAMi | SSF48310, SSF48310, 1 hit SSF56228, SSF56228, 1 hit |
i Sequence
Sequence statusi: Complete.
P76192-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MANGWTGNIL RVNLTTGNIT LEDSSKFKSF VGGMGFGYKI MYDEVPPGTK
60 70 80 90 100
PFDEANKLVF ATGPLTGSGA PCSSRVNITS LSTFTKGNLV VDAHMGGFFA
110 120 130 140 150
AQMKFAGYDV IIIEGKAKSP VWLKIKDDKV SLEKADFLWG KGTRATTEEI
160 170 180 190 200
CRLTSPETCV AAIGQAGENL VPLSGMLNSR NHSGGAGTGA IMGSKNLKAI
210 220 230 240 250
AVEGTKGVNI ADRQEMKRLN DYMMTELIGA NNNHVVPSTP QSWAEYSDPK
260 270 280 290 300
SRWTARKGLF WGAAEGGPIE TGEIPPGNQN TVGFRTYKSV FDLGPAAEKY
310 320 330 340 350
TVKMSGCHSC PIRCMTQMNI PRVKEFGVPS TGGNTCVANF VHTTIFPNGP
360 370 380 390 400
KDFEDKDDGR VIGNLVGLNL FDDYGLWCNY GQLHRDFTYC YSKGVFKRVL
410 420 430 440 450
PAEEYAEIRW DQLEAGDVNF IKDFYYRLAH RVGELSHLAD GSYAIAERWN
460 470 480 490 500
LGEEYWGYAK NKLWSPFGYP VHHANEASAQ VGSIVNCMFN RDCMTHTHIN
510 520 530 540 550
FIGSGLPLKL QREVAKELFG SEDAYDETKN YTPINDAKIK YAKWSLLRVC
560 570 580 590 600
LHNAVTLCNW VWPMTVSPLK SRNYRGDLAL EAKFFKAITG EEMTQEKLDL
610 620 630 640 650
AAERIFTLHR AYTVKLMQTK DMRNEHDLIC SWVFDKDPQI PVFTEGTDKM
660 670 680 690 700
DRDDMHASLT MFYKEMGWDP QLGCPTRETL QRLGLEDIAA DLAAHNLLPA
Sequence cautioni
The sequence AAB47949 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U68703 Genomic DNA Translation: AAB47949.1 Different initiation. U00096 Genomic DNA Translation: AAC74743.1 AP009048 Genomic DNA Translation: BAE76498.1 |
PIRi | A64925 |
RefSeqi | NP_416188.1, NC_000913.3 WP_001273527.1, NZ_SSZK01000001.1 |
Genome annotation databases
EnsemblBacteriai | AAC74743; AAC74743; b1673 BAE76498; BAE76498; BAE76498 |
GeneIDi | 57731069 948756 |
KEGGi | ecj:JW5272 eco:b1673 |
PATRICi | fig|1411691.4.peg.586 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U68703 Genomic DNA Translation: AAB47949.1 Different initiation. U00096 Genomic DNA Translation: AAC74743.1 AP009048 Genomic DNA Translation: BAE76498.1 |
PIRi | A64925 |
RefSeqi | NP_416188.1, NC_000913.3 WP_001273527.1, NZ_SSZK01000001.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4260274, 6 interactors |
STRINGi | 511145.b1673 |
Proteomic databases
jPOSTi | P76192 |
PaxDbi | P76192 |
PRIDEi | P76192 |
Genome annotation databases
EnsemblBacteriai | AAC74743; AAC74743; b1673 BAE76498; BAE76498; BAE76498 |
GeneIDi | 57731069 948756 |
KEGGi | ecj:JW5272 eco:b1673 |
PATRICi | fig|1411691.4.peg.586 |
Organism-specific databases
EchoBASEi | EB3714 |
Phylogenomic databases
eggNOGi | COG2414, Bacteria |
HOGENOMi | CLU_020364_0_0_6 |
InParanoidi | P76192 |
PhylomeDBi | P76192 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6901-MONOMER |
Miscellaneous databases
PROi | PR:P76192 |
Family and domain databases
Gene3Di | 1.10.569.10, 1 hit 1.10.599.10, 1 hit 3.60.9.10, 1 hit |
InterProi | View protein in InterPro IPR013984, Ald_Fedxn_OxRdtase_dom2 IPR013985, Ald_Fedxn_OxRdtase_dom3 IPR013983, Ald_Fedxn_OxRdtase_N IPR036503, Ald_Fedxn_OxRdtase_N_sf IPR001203, OxRdtase_Ald_Fedxn_C IPR036021, Tungsten_al_ferr_oxy-like_C |
Pfami | View protein in Pfam PF01314, AFOR_C, 1 hit PF02730, AFOR_N, 1 hit |
SMARTi | View protein in SMART SM00790, AFOR_N, 1 hit |
SUPFAMi | SSF48310, SSF48310, 1 hit SSF56228, SSF56228, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YDHV_ECOLI | |
Accessioni | P76192Primary (citable) accession number: P76192 Secondary accession number(s): P71277, Q2MB58 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | February 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 127 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families