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Protein

1,2-phenylacetyl-CoA epoxidase, subunit B

Gene

paaB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of 1,2-phenylacetyl-CoA epoxidase multicomponent enzyme system which catalyzes the reduction of phenylacetyl-CoA (PA-CoA) to form 1,2-epoxyphenylacetyl-CoA. The subunit B may play a regulatory role or be directly involved in electron transport.3 Publications

Pathwayi: phenylacetate degradation

This protein is involved in the pathway phenylacetate degradation, which is part of Aromatic compound metabolism.
View all proteins of this organism that are known to be involved in the pathway phenylacetate degradation and in Aromatic compound metabolism.

GO - Biological processi

  • phenylacetate catabolic process Source: UniProtKB

Enzyme and pathway databases

BioCyciEcoCyc:G6710-MONOMER
MetaCyc:G6710-MONOMER
UniPathwayiUPA00930

Names & Taxonomyi

Protein namesi
Recommended name:
1,2-phenylacetyl-CoA epoxidase, subunit B
Alternative name(s):
1,2-phenylacetyl-CoA monooxygenase, subunit B
Gene namesi
Name:paaB
Synonyms:ynbF
Ordered Locus Names:b1389, JW1384
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14299 paaB

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000581601 – 951,2-phenylacetyl-CoA epoxidase, subunit BAdd BLAST95

Proteomic databases

PaxDbiP76078
PRIDEiP76078

Expressioni

Inductioni

Activated by cAMP receptor protein (CRP), integration host factor (IHF) and by phenylacetyl-coenzyme A (PA-CoA) that prevents PaaX from binding its target sequences. Inhibited by PaaX.2 Publications

Interactioni

Subunit structurei

Homotrimer. Forms a stable heterodimer with PaaC. Probably forms an oligomer with PaaAC.1 Publication

Protein-protein interaction databases

BioGridi4261630, 132 interactors
IntActiP76078, 12 interactors
STRINGi316385.ECDH10B_1514

Structurei

3D structure databases

ProteinModelPortaliP76078
SMRiP76078
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105N76 Bacteria
COG3460 LUCA
HOGENOMiHOG000249734
InParanoidiP76078
KOiK02610
OMAiRNGLAHK
PhylomeDBiP76078

Family and domain databases

Gene3Di3.10.20.520, 1 hit
InterProiView protein in InterPro
IPR009359 PaaB
IPR038693 PaaB_sf
PfamiView protein in Pfam
PF06243 PaaB, 1 hit
PIRSFiPIRSF030200 PaaB, 1 hit
TIGRFAMsiTIGR02157 PA_CoA_Oxy2, 1 hit

Sequencei

Sequence statusi: Complete.

P76078-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNVYWPLYE VFVRGKQGLS HRHVGSLHAA DERMALENAR DAYTRRSEGC
60 70 80 90
SIWVVKASEI VASQPEERGE FFDPAESKVY RHPTFYTIPD GIEHM
Length:95
Mass (Da):10,942
Last modified:February 1, 1997 - v1
Checksum:iD2866DB428CF90AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97452 Genomic DNA Translation: CAA66091.1
U00096 Genomic DNA Translation: AAC74471.1
AP009048 Genomic DNA Translation: BAE76424.1
PIRiH64889
RefSeqiNP_415907.1, NC_000913.3
WP_000073393.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74471; AAC74471; b1389
BAE76424; BAE76424; BAE76424
GeneIDi947595
KEGGiecj:JW1384
eco:b1389
PATRICifig|1411691.4.peg.882

Similar proteinsi

Entry informationi

Entry nameiPAAB_ECOLI
AccessioniPrimary (citable) accession number: P76078
Secondary accession number(s): Q2MBD2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: April 25, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

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