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Protein

Citrate lyase alpha chain

Gene

citF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Represents a citrate:acetyl-ACP transferase.By similarity

Catalytic activityi

Citrate = acetate + oxaloacetate.
Acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase, Transferase

Enzyme and pathway databases

BioCyciEcoCyc:CITTRANS-MONOMER
MetaCyc:CITTRANS-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate lyase alpha chain (EC:4.1.3.6)
Short name:
Citrase alpha chain
Alternative name(s):
Citrate (pro-3S)-lyase alpha chain
Citrate CoA-transferase subunit (EC:2.8.3.10)
Gene namesi
Name:citF
Synonyms:ybdV
Ordered Locus Names:b0615, JW5087
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13541 citF

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000897521 – 510Citrate lyase alpha chainAdd BLAST510

Proteomic databases

PaxDbiP75726
PRIDEiP75726

Expressioni

Inductioni

Repressed by H-NS. Part of the citCDEFXG operon.1 Publication

Interactioni

Subunit structurei

Oligomer with a subunit composition of (alpha,beta, gamma)6.By similarity

Protein-protein interaction databases

BioGridi4261998, 7 interactors
STRINGi316385.ECDH10B_0683

Structurei

3D structure databases

ProteinModelPortaliP75726
SMRiP75726
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105CHY Bacteria
COG3051 LUCA
HOGENOMiHOG000117923
InParanoidiP75726
KOiK01643
OMAiKGSVINQ
PhylomeDBiP75726

Family and domain databases

InterProiView protein in InterPro
IPR006472 Citrate_lyase_asu
IPR037171 NagB/RpiA_transferase-like
PANTHERiPTHR40596 PTHR40596, 1 hit
PfamiView protein in Pfam
PF04223 CitF, 1 hit
PIRSFiPIRSF009451 Citrt_lyas_alpha, 1 hit
SUPFAMiSSF100950 SSF100950, 2 hits
TIGRFAMsiTIGR01584 citF, 1 hit

Sequencei

Sequence statusi: Complete.

P75726-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQKIEQSQR QERVAAWNRR AECDLAAFQN SPKQTYQAEK ARDRKLCANL
60 70 80 90 100
EEAIRRSGLQ DGMTVSFHHA FRGGDLTVNM VMDVIAKMGF KNLTLASSSL
110 120 130 140 150
SDCHAPLVEH IRQGVVTRIY TSGLRGPLAE EISRGLLAEP VQIHSHGGRV
160 170 180 190 200
HLVQSGELNI DVAFLGVPSC DEFGNANGYT GKACCGSLGY AIVDADNAKQ
210 220 230 240 250
VVMLTEELLP YPHNPASIEQ DQVDLIVKVD RVGDAAKIGA GATRMTTNPR
260 270 280 290 300
ELLIARSAAD VIVNSGYFKE GFSMQTGTGG ASLAVTRFLE DKMRSRDIRA
310 320 330 340 350
DFALGGITAT MVDLHEKGLI RKLLDVQSFD SHAAQSLARN PNHIEISANQ
360 370 380 390 400
YANWGSKGAS VDRLDVVVLS ALEIDTQFNV NVLTGSDGVL RGASGGHCDT
410 420 430 440 450
AIASALSIIV APLVRGRIPT LVDNVLTCIT PGSSVDILVT DHGIAVNPAR
460 470 480 490 500
PELAERLQEA GIKVVSIEWL RERARLLTGE PQPIEFTDRV VAVVRYRDGS
510
VIDVVHQVKE
Length:510
Mass (Da):55,173
Last modified:February 1, 1997 - v1
Checksum:iCA466F1620D8EB92
GO

Sequence cautioni

The sequence AAB40815 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA Translation: AAB40815.1 Different initiation.
U00096 Genomic DNA Translation: AAC73716.1
AP009048 Genomic DNA Translation: BAA35251.2
PIRiE64795
RefSeqiNP_415148.1, NC_000913.3
WP_000192242.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73716; AAC73716; b0615
BAA35251; BAA35251; BAA35251
GeneIDi945230
KEGGiecj:JW5087
eco:b0615
PATRICifig|1411691.4.peg.1653

Similar proteinsi

Entry informationi

Entry nameiCILA_ECOLI
AccessioniPrimary (citable) accession number: P75726
Secondary accession number(s): P77102, Q9R7T5, Q9R7T6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

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