UniProtKB - P75712 (ALLP_ECOLI)
Protein
Putative allantoin permease
Gene
ybbW
Organism
Escherichia coli (strain K12)
Status
Functioni
Transport of allantoin.By similarity
GO - Molecular functioni
- nucleobase transmembrane transporter activity Source: GO_Central
GO - Biological processi
- nucleobase transport Source: GO_Central
- purine nucleobase metabolic process Source: UniProtKB-KW
Keywordsi
Biological process | Purine metabolism, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:B0511-MONOMER |
Protein family/group databases
TCDBi | 2.A.39.3.8, the nucleobase:cation symporter-1 (ncs1) family |
Names & Taxonomyi
Protein namesi | Recommended name: Putative allantoin permeaseAlternative name(s): Allantoin transport protein |
Gene namesi | Name:ybbW Synonyms:glxB2 Ordered Locus Names:b0511, JW0499 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 34 | CytoplasmicSequence analysisAdd BLAST | 34 | |
Transmembranei | 35 – 55 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 56 – 58 | PeriplasmicSequence analysis | 3 | |
Transmembranei | 59 – 79 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 80 – 114 | CytoplasmicSequence analysisAdd BLAST | 35 | |
Transmembranei | 115 – 135 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 136 – 155 | PeriplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 156 – 176 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 177 – 190 | CytoplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 191 – 211 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 212 – 224 | PeriplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 225 – 245 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 246 – 265 | CytoplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 266 – 286 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 287 – 306 | PeriplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 307 – 327 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 328 – 346 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 347 – 367 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 368 – 372 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 373 – 393 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 394 – 425 | CytoplasmicSequence analysisAdd BLAST | 32 | |
Transmembranei | 426 – 446 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 447 | PeriplasmicSequence analysis | 1 | |
Transmembranei | 448 – 468 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 469 – 484 | CytoplasmicSequence analysisAdd BLAST | 16 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000197930 | 1 – 484 | Putative allantoin permeaseAdd BLAST | 484 |
Proteomic databases
PaxDbi | P75712 |
PRIDEi | P75712 |
Expressioni
Inductioni
By glyoxylate.
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262820, 183 interactors |
STRINGi | 511145.b0511 |
Family & Domainsi
Sequence similaritiesi
Belongs to the purine-cytosine permease (2.A.39) family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1953, Bacteria |
HOGENOMi | CLU_021555_0_0_6 |
InParanoidi | P75712 |
PhylomeDBi | P75712 |
Family and domain databases
Gene3Di | 1.10.4160.10, 1 hit |
InterProi | View protein in InterPro IPR012681, NCS1 IPR001248, Pur-cyt_permease IPR038271, Pur-cyt_permease_sf |
Pfami | View protein in Pfam PF02133, Transp_cyt_pur, 1 hit |
TIGRFAMsi | TIGR00800, ncs1, 1 hit |
i Sequence
Sequence statusi: Complete.
P75712-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEHQRKLFQQ RGYSEDLLPK TQSQRTWKTF NYFTLWMGSV HNVPNYVMVG
60 70 80 90 100
GFFILGLSTF SIMLAIILSA FFIAAVMVLN GAAGSKYGVP FAMILRASYG
110 120 130 140 150
VRGALFPGLL RGGIAAIMWF GLQCYAGSLA CLILIGKIWP GFLTLGGDFT
160 170 180 190 200
LLGLSLPGLI TFLIFWLVNV GIGFGGGKVL NKFTAILNPC IYIVFGGMAI
210 220 230 240 250
WAISLVGIGP IFDYIPSGIQ KAENGGFLFL VVINAVVAVW AAPAVSASDF
260 270 280 290 300
TQNAHSFREQ ALGQTLGLVV AYILFAVAGV CIIAGASIHY GADTWNVLDI
310 320 330 340 350
VQRWDSLFAS FFAVLVILMT TISTNATGNI IPAGYQIAAI APTKLTYKNG
360 370 380 390 400
VLIASIISLL ICPWKLMENQ DSIYLFLDII GGMLGPVIGV MMAHYFVVMR
410 420 430 440 450
GQINLDELYT APGDYKYYDN GFNLTAFSVT LVAVILSLGG KFIHFMEPLS
460 470 480
RVSWFVGVIV AFAAYALLKK RTTAEKTGEQ KTIG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U89279 Genomic DNA Translation: AAB93852.1 U82664 Genomic DNA Translation: AAB40263.1 U00096 Genomic DNA Translation: AAC73613.2 AP009048 Genomic DNA Translation: BAE76289.1 |
PIRi | F64782 |
RefSeqi | NP_415044.4, NC_000913.3 WP_000401100.1, NZ_SSZK01000024.1 |
Genome annotation databases
EnsemblBacteriai | AAC73613; AAC73613; b0511 BAE76289; BAE76289; BAE76289 |
GeneIDi | 57731388 945138 |
KEGGi | ecj:JW0499 eco:b0511 |
PATRICi | fig|1411691.4.peg.1767 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U89279 Genomic DNA Translation: AAB93852.1 U82664 Genomic DNA Translation: AAB40263.1 U00096 Genomic DNA Translation: AAC73613.2 AP009048 Genomic DNA Translation: BAE76289.1 |
PIRi | F64782 |
RefSeqi | NP_415044.4, NC_000913.3 WP_000401100.1, NZ_SSZK01000024.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4262820, 183 interactors |
STRINGi | 511145.b0511 |
Protein family/group databases
TCDBi | 2.A.39.3.8, the nucleobase:cation symporter-1 (ncs1) family |
Proteomic databases
PaxDbi | P75712 |
PRIDEi | P75712 |
Genome annotation databases
EnsemblBacteriai | AAC73613; AAC73613; b0511 BAE76289; BAE76289; BAE76289 |
GeneIDi | 57731388 945138 |
KEGGi | ecj:JW0499 eco:b0511 |
PATRICi | fig|1411691.4.peg.1767 |
Organism-specific databases
EchoBASEi | EB3383 |
Phylogenomic databases
eggNOGi | COG1953, Bacteria |
HOGENOMi | CLU_021555_0_0_6 |
InParanoidi | P75712 |
PhylomeDBi | P75712 |
Enzyme and pathway databases
BioCyci | EcoCyc:B0511-MONOMER |
Miscellaneous databases
PROi | PR:P75712 |
Family and domain databases
Gene3Di | 1.10.4160.10, 1 hit |
InterProi | View protein in InterPro IPR012681, NCS1 IPR001248, Pur-cyt_permease IPR038271, Pur-cyt_permease_sf |
Pfami | View protein in Pfam PF02133, Transp_cyt_pur, 1 hit |
TIGRFAMsi | TIGR00800, ncs1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ALLP_ECOLI | |
Accessioni | P75712Primary (citable) accession number: P75712 Secondary accession number(s): P77127, Q2MBR7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 137 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families