ybbW

Protein namesⁱ	Recommended name: Putative allantoin permease Alternative name(s): Allantoin transport protein
Gene namesⁱ	Name:ybbW Synonyms:glxB2 Ordered Locus Names:b0511, JW0499
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG13618 ybbW

EcoGeneⁱ

EG13618 ybbW

Subcellular locationⁱ

Cell inner membrane ; Multi-pass membrane protein

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 34	CytoplasmicSequence analysisAdd BLAST	34
Transmembraneⁱ	35 – 55	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	56 – 58	PeriplasmicSequence analysis	3
Transmembraneⁱ	59 – 79	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	80 – 114	CytoplasmicSequence analysisAdd BLAST	35
Transmembraneⁱ	115 – 135	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	136 – 155	PeriplasmicSequence analysisAdd BLAST	20
Transmembraneⁱ	156 – 176	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	177 – 190	CytoplasmicSequence analysisAdd BLAST	14
Transmembraneⁱ	191 – 211	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	212 – 224	PeriplasmicSequence analysisAdd BLAST	13
Transmembraneⁱ	225 – 245	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	246 – 265	CytoplasmicSequence analysisAdd BLAST	20
Transmembraneⁱ	266 – 286	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	287 – 306	PeriplasmicSequence analysisAdd BLAST	20
Transmembraneⁱ	307 – 327	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	328 – 346	CytoplasmicSequence analysisAdd BLAST	19
Transmembraneⁱ	347 – 367	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	368 – 372	PeriplasmicSequence analysis	5
Transmembraneⁱ	373 – 393	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	394 – 425	CytoplasmicSequence analysisAdd BLAST	32
Transmembraneⁱ	426 – 446	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	447	PeriplasmicSequence analysis	1
Transmembraneⁱ	448 – 468	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	469 – 484	CytoplasmicSequence analysisAdd BLAST	16

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW
plasma membrane
Source: EcoCyc
Inferred from direct assayⁱ
- 15919996

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cell inner membrane, Cell membrane, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000197930	1 – 484	Putative allantoin permeaseAdd BLAST		484

Proteomic databases

PaxDbⁱ	P75712
PRIDEⁱ	P75712

Expressionⁱ

Inductionⁱ

By glyoxylate.

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	4262820, 183 interactors
STRINGⁱ	316385.ECDH10B_0467

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P75712
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the purine-cytosine permease (2.A.39) family.Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG4105EW8 Bacteria COG1953 LUCA
HOGENOMⁱ	HOG000165632
InParanoidⁱ	P75712
KEGG Orthology (KO) More...KOⁱ	K10975
OMAⁱ	FMWIGDG
PhylomeDBⁱ	P75712

Family and domain databases

Gene3Dⁱ	1.10.4160.10, 1 hit
InterProⁱ	View protein in InterPro IPR012681 NCS1 IPR001248 Pur-cyt_permease IPR038271 Pur-cyt_permease_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02133 Transp_cyt_pur, 1 hit
TIGRFAMsⁱ	TIGR00800 ncs1, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P75712-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEHQRKLFQQ RGYSEDLLPK TQSQRTWKTF NYFTLWMGSV HNVPNYVMVG 
        60         70         80         90        100
GFFILGLSTF SIMLAIILSA FFIAAVMVLN GAAGSKYGVP FAMILRASYG 
       110        120        130        140        150
VRGALFPGLL RGGIAAIMWF GLQCYAGSLA CLILIGKIWP GFLTLGGDFT 
       160        170        180        190        200
LLGLSLPGLI TFLIFWLVNV GIGFGGGKVL NKFTAILNPC IYIVFGGMAI 
       210        220        230        240        250
WAISLVGIGP IFDYIPSGIQ KAENGGFLFL VVINAVVAVW AAPAVSASDF 
       260        270        280        290        300
TQNAHSFREQ ALGQTLGLVV AYILFAVAGV CIIAGASIHY GADTWNVLDI 
       310        320        330        340        350
VQRWDSLFAS FFAVLVILMT TISTNATGNI IPAGYQIAAI APTKLTYKNG 
       360        370        380        390        400
VLIASIISLL ICPWKLMENQ DSIYLFLDII GGMLGPVIGV MMAHYFVVMR 
       410        420        430        440        450
GQINLDELYT APGDYKYYDN GFNLTAFSVT LVAVILSLGG KFIHFMEPLS 
       460        470        480 
RVSWFVGVIV AFAAYALLKK RTTAEKTGEQ KTIG

Length:484

Mass (Da):52,456

Last modified:November 1, 1997 - v2

Checksum:ⁱAE3DA5FF5043BF62

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U89279 Genomic DNA Translation: AAB93852.1 U82664 Genomic DNA Translation: AAB40263.1 U00096 Genomic DNA Translation: AAC73613.2 AP009048 Genomic DNA Translation: BAE76289.1
PIRⁱ	F64782
NCBI Reference Sequences More...RefSeqⁱ	NP_415044.4, NC_000913.3 WP_000401100.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaⁱ	AAC73613; AAC73613; b0511 BAE76289; BAE76289; BAE76289
GeneIDⁱ	945138
KEGGⁱ	ecj:JW0499 eco:b0511
PATRICⁱ	fig\|1411691.4.peg.1767

Protein	Similar proteins		Species	Score	Length	Source
P75712	Allantoin permease		ECOLX		484	UniRef100_P75712
Allantoin permease		Escherichia coli O111:NM str. K6722		484
Putative allantoin permease		Escherichia coli 1-110-08_S3_C1		484
Allantoin permease		Escherichia coli ATCC BAA-2209		484
Permease, cytosine/purine, uracil, thiamine, allantoin family		Escherichia coli 53638		484
+29

Protein	Similar proteins		Species	Score	Length	Source
P75712	Allantoin permease		ECOLX		484	UniRef90_P75712
Allantoin permease		Escherichia coli O111:NM str. K6722		484
Putative allantoin permease		Escherichia coli 1-110-08_S3_C1		484
Allantoin permease		Escherichia coli ATCC BAA-2209		484
Permease, cytosine/purine, uracil, thiamine, allantoin family		Escherichia coli 53638		484
+1020

Protein	Similar proteins		Species	Score	Length	Source
P75712	Putative purine permease YbbY		ECOLI		433	UniRef50_P75712
Allantoin permease		ECOLX		484
Allantoin permease		Escherichia coli O111:NM str. K6722		484
Putative allantoin permease		Escherichia coli 1-110-08_S3_C1		484
Allantoin permease		Escherichia coli ATCC BAA-2209		484
+1742

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U89279 Genomic DNA Translation: AAB93852.1 U82664 Genomic DNA Translation: AAB40263.1 U00096 Genomic DNA Translation: AAC73613.2 AP009048 Genomic DNA Translation: BAE76289.1
PIRⁱ	F64782
RefSeqⁱ	NP_415044.4, NC_000913.3 WP_000401100.1, NZ_LN832404.1

3D structure databases

ProteinModelPortalⁱ	P75712
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	4262820, 183 interactors
STRINGⁱ	316385.ECDH10B_0467

Protein family/group databases

TCDBⁱ	2.A.39.3.8 the nucleobase:cation symporter-1 (ncs1) family

TCDBⁱ

2.A.39.3.8 the nucleobase:cation symporter-1 (ncs1) family

Proteomic databases

PaxDbⁱ	P75712
PRIDEⁱ	P75712

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAC73613; AAC73613; b0511 BAE76289; BAE76289; BAE76289
GeneIDⁱ	945138
KEGGⁱ	ecj:JW0499 eco:b0511
PATRICⁱ	fig\|1411691.4.peg.1767

Organism-specific databases

EchoBASEⁱ	EB3383
EcoGeneⁱ	EG13618 ybbW

Phylogenomic databases

eggNOGⁱ	ENOG4105EW8 Bacteria COG1953 LUCA
HOGENOMⁱ	HOG000165632
InParanoidⁱ	P75712
KOⁱ	K10975
OMAⁱ	FMWIGDG
PhylomeDBⁱ	P75712

Enzyme and pathway databases

BioCycⁱ	EcoCyc:B0511-MONOMER

BioCycⁱ

EcoCyc:B0511-MONOMER

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P75712

PROⁱ

PR:P75712

Family and domain databases

Gene3Dⁱ	1.10.4160.10, 1 hit
InterProⁱ	View protein in InterPro IPR012681 NCS1 IPR001248 Pur-cyt_permease IPR038271 Pur-cyt_permease_sf
Pfamⁱ	View protein in Pfam PF02133 Transp_cyt_pur, 1 hit
TIGRFAMsⁱ	TIGR00800 ncs1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ALLP_ECOLI
Accessionⁱ	P75712Primary (citable) accession number: P75712 Secondary accession number(s): P77127, Q2MBR7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
	Last sequence update:	November 1, 1997
	Last modified:	March 28, 2018
	This is version 122 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P75712 (ALLP_ECOLI)

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Putative allantoin permease

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

GO - Cellular componenti

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ