UniProtKB - P75292 (ULAC_MYCPN)
Protein
Ascorbate-specific PTS system EIIA component
Gene
ulaC
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Functioni
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 71 | Tele-phosphohistidine intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- kinase activity Source: UniProtKB-KW
GO - Biological processi
- phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW
Keywordsi
Molecular function | Kinase, Transferase |
Biological process | Phosphotransferase system, Transport |
Enzyme and pathway databases
BioCyci | MPNE272634:G1GJ3-811-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Ascorbate-specific PTS system EIIA componentBy similarityAlternative name(s): Ascorbate-specific phosphotransferase enzyme IIA componentBy similarity |
Gene namesi | Name:ulaC Synonyms:sgaA Ordered Locus Names:MPN_494 ORF Names:MP348 |
Organismi | Mycoplasma pneumoniae (strain ATCC 29342 / M129) |
Taxonomic identifieri | 272634 [NCBI] |
Taxonomic lineagei | Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm Curated
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000186685 | 1 – 159 | Ascorbate-specific PTS system EIIA componentAdd BLAST | 159 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 71 | PhosphohistidineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 9 – 152 | PTS EIIA type-2PROSITE-ProRule annotationAdd BLAST | 144 |
Domaini
The PTS EIIA type-2 domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the PTS EIIB type-2 domain.PROSITE-ProRule annotation
Phylogenomic databases
HOGENOMi | CLU_072531_2_0_14 |
OMAi | MGPYIIL |
Family and domain databases
CDDi | cd00211, PTS_IIA_fru, 1 hit |
Gene3Di | 3.40.930.10, 1 hit |
InterProi | View protein in InterPro IPR016152, PTrfase/Anion_transptr IPR002178, PTS_EIIA_type-2_dom |
Pfami | View protein in Pfam PF00359, PTS_EIIA_2, 1 hit |
SUPFAMi | SSF55804, SSF55804, 1 hit |
PROSITEi | View protein in PROSITE PS51094, PTS_EIIA_TYPE_2, 1 hit PS00372, PTS_EIIA_TYPE_2_HIS, 1 hit |
i Sequence
Sequence statusi: Complete.
P75292-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTKLDFKAVL KQHHTVRLHQ TAQDWKQAIQ LCIHPLIAAK LVQPAYFDDI
60 70 80 90 100
LKSVAQYGPY FIIAENVAMP HAQNNGTVQQ NCFSLVTLKE PVYFDNDPRP
110 120 130 140 150
VRLLIGLAAT SAAIHTTEAL PQIAALVEDT QVVKDLLDCC DETSLFAVID
RVNLHKYLT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00089 Genomic DNA Translation: AAB95996.1 |
PIRi | S73674 |
RefSeqi | NP_110182.1, NC_000912.1 WP_010874850.1, NC_000912.1 |
Genome annotation databases
EnsemblBacteriai | AAB95996; AAB95996; MPN_494 |
GeneIDi | 45596382 |
KEGGi | mpn:MPN494 |
PATRICi | fig|272634.6.peg.534 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00089 Genomic DNA Translation: AAB95996.1 |
PIRi | S73674 |
RefSeqi | NP_110182.1, NC_000912.1 WP_010874850.1, NC_000912.1 |
3D structure databases
SMRi | P75292 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | AAB95996; AAB95996; MPN_494 |
GeneIDi | 45596382 |
KEGGi | mpn:MPN494 |
PATRICi | fig|272634.6.peg.534 |
Phylogenomic databases
HOGENOMi | CLU_072531_2_0_14 |
OMAi | MGPYIIL |
Enzyme and pathway databases
BioCyci | MPNE272634:G1GJ3-811-MONOMER |
Family and domain databases
CDDi | cd00211, PTS_IIA_fru, 1 hit |
Gene3Di | 3.40.930.10, 1 hit |
InterProi | View protein in InterPro IPR016152, PTrfase/Anion_transptr IPR002178, PTS_EIIA_type-2_dom |
Pfami | View protein in Pfam PF00359, PTS_EIIA_2, 1 hit |
SUPFAMi | SSF55804, SSF55804, 1 hit |
PROSITEi | View protein in PROSITE PS51094, PTS_EIIA_TYPE_2, 1 hit PS00372, PTS_EIIA_TYPE_2_HIS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ULAC_MYCPN | |
Accessioni | P75292Primary (citable) accession number: P75292 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | February 1, 1997 | |
Last modified: | April 7, 2021 | |
This is version 98 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |