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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPNE272634:G1GJ3-912-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:MPN_556
ORF Names:MP286
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000808 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515781 – 537Arginine--tRNA ligaseAdd BLAST537

Proteomic databases

PRIDEiP75222

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

IntActiP75222, 2 interactors

Structurei

3D structure databases

ProteinModelPortaliP75222
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi113 – 123"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

P75222-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFINTDLQE CLNALNLEFD EHKELVKLVK NNSFSGFAST VVFHLKGVNQ
60 70 80 90 100
KETAQQIAAW LLKHKKAHYR RVFVANNNFI NFEISPQKYL DFLKTKPTFA
110 120 130 140 150
PKPTKVLIEW VSANPTGELH LGHVRNAFFG HVLNNLMVFL GFQTVREYWV
160 170 180 190 200
NDYGQQARVF GFSVYQALHL QQNIKVTPHP DGYEGELVDS IAKTITGIPL
210 220 230 240 250
DKLSFEEFLQ QPFLDQLLAD CTAKVLEVIK QDLATIHIHF DSWKFESQVV
260 270 280 290 300
KETDYKKLLT QFKDEAHYEK DGAIWLKTTL YGDDKDRVLV RQDNRPSYFG
310 320 330 340 350
TDVAYHLDKA ARGFDLLYDI WGSDHEGHIK RMHCVYEGLK IHQKCQLKIT
360 370 380 390 400
ALQLVMLYKN KEIVRLSKRA GNVITIKQML QMLSEDAARW FMLSQTNNSI
410 420 430 440 450
IKIDLDTANL QNSSNPVYYV QYAYARMCSV LKVVDQAALA QVNDCSLLTH
460 470 480 490 500
EKEIALLDQL VYFKSLLEKV QVSHELHLLT NYLYETATLF HSWYKACKIN
510 520 530
DPAQYNLTQQ RLLLLQSLHH VFGQLLQILN ITAPQQM
Length:537
Mass (Da):62,121
Last modified:February 1, 1997 - v1
Checksum:i099B1C0DC33A39B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA Translation: AAB95934.1
PIRiS73612
RefSeqiNP_110245.1, NC_000912.1
WP_010874913.1, NC_000912.1

Genome annotation databases

EnsemblBacteriaiAAB95934; AAB95934; MPN_556
GeneIDi877288
KEGGimpn:MPN556
PATRICifig|272634.6.peg.618

Similar proteinsi

Entry informationi

Entry nameiSYR_MYCPN
AccessioniPrimary (citable) accession number: P75222
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

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