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Protein

Colanic acid biosynthesis protein WcaK

Gene

wcaK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Pathwayi: slime polysaccharide biosynthesis

This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.
View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processLipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:G7096-MONOMER
UniPathwayi
UPA00936

Names & Taxonomyi

Protein namesi
Recommended name:
Colanic acid biosynthesis protein WcaK (EC:2.-.-.-)
Gene namesi
Name:wcaK
Ordered Locus Names:b2045, JW2030
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13577 wcaK

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000732161 – 426Colanic acid biosynthesis protein WcaKAdd BLAST426

Proteomic databases

PaxDbiP71242
PRIDEiP71242

Interactioni

Protein-protein interaction databases

BioGridi4261185, 158 interactors
IntActiP71242, 21 interactors
STRINGi316385.ECDH10B_2195

Structurei

3D structure databases

ProteinModelPortaliP71242
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C74 Bacteria
COG2327 LUCA
HOGENOMiHOG000121954
InParanoidiP71242
KOiK16710

Family and domain databases

InterProiView protein in InterPro
IPR023918 Colanic_acid_synth_WcaK
IPR007345 Polysacch_pyruvyl_Trfase
PfamiView protein in Pfam
PF04230 PS_pyruv_trans, 1 hit
TIGRFAMsiTIGR04006 wcaK, 1 hit

Sequencei

Sequence statusi: Complete.

P71242-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLLILGNHT CGNRGDSAIL RGLLDAINIL NPHAEVDVMS RYPVSSSWLL
60 70 80 90 100
NRPVMGDPLF LQMKQHNSAA GVVGRVKKVL RRRYQHQVLL SRVTDTGKLR
110 120 130 140 150
NIAIAQGFTD FVRLLSGYDA IIQVGGSFFV DLYGVPQFEH ALCTFMAKKP
160 170 180 190 200
LFMIGHSVGP FQDEQFNQLA NYVFGHCDAL ILRESVSFDL MKRSNITTAK
210 220 230 240 250
VEHGVDTAWL VDHHTEDFTA SYAVQHWLDV AAQQKTVAIT LRELAPFDKR
260 270 280 290 300
LGTTQQAYEK AFAGVVNRIL DEGYQVIALS TCTGIDSYNK DDRMVALNLR
310 320 330 340 350
QHISDPARYH VVMDELNDLE MGKILGACEL TVGTRLHSAI ISMNFATPAI
360 370 380 390 400
AINYEHKSAG IMQQLGLPEM AIDIRHLLDG SLQAMVADTL GQLPALNARL
410 420
SEAVSRERQT GMQMVQSVLE RIGEVK
Length:426
Mass (Da):47,344
Last modified:November 1, 1997 - v2
Checksum:iF0B7D87A9A3E594C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti77K → I in AAC77850 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA Translation: AAC77850.1
U00096 Genomic DNA Translation: AAC75106.1
AP009048 Genomic DNA Translation: BAE76571.1
PIRiD64970
RefSeqiNP_416549.1, NC_000913.3
WP_000770780.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75106; AAC75106; b2045
BAE76571; BAE76571; BAE76571
GeneIDi946569
KEGGiecj:JW2030
eco:b2045
PATRICifig|1411691.4.peg.206

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA Translation: AAC77850.1
U00096 Genomic DNA Translation: AAC75106.1
AP009048 Genomic DNA Translation: BAE76571.1
PIRiD64970
RefSeqiNP_416549.1, NC_000913.3
WP_000770780.1, NZ_LN832404.1

3D structure databases

ProteinModelPortaliP71242
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261185, 158 interactors
IntActiP71242, 21 interactors
STRINGi316385.ECDH10B_2195

Proteomic databases

PaxDbiP71242
PRIDEiP71242

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75106; AAC75106; b2045
BAE76571; BAE76571; BAE76571
GeneIDi946569
KEGGiecj:JW2030
eco:b2045
PATRICifig|1411691.4.peg.206

Organism-specific databases

EchoBASEiEB3347
EcoGeneiEG13577 wcaK

Phylogenomic databases

eggNOGiENOG4105C74 Bacteria
COG2327 LUCA
HOGENOMiHOG000121954
InParanoidiP71242
KOiK16710

Enzyme and pathway databases

UniPathwayi
UPA00936

BioCyciEcoCyc:G7096-MONOMER

Miscellaneous databases

PROiPR:P71242

Family and domain databases

InterProiView protein in InterPro
IPR023918 Colanic_acid_synth_WcaK
IPR007345 Polysacch_pyruvyl_Trfase
PfamiView protein in Pfam
PF04230 PS_pyruv_trans, 1 hit
TIGRFAMsiTIGR04006 wcaK, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiWCAK_ECOLI
AccessioniPrimary (citable) accession number: P71242
Secondary accession number(s): P76380, Q2MAY5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 7, 2018
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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