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UniProtKB - P71019 (FABD_BACSU)
Protein
Malonyl CoA-acyl carrier protein transacylase
Gene
fabD
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Catalytic activityi
- EC:2.3.1.39
: fatty acid biosynthesis Pathwayi
This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 91 | By similarity | 1 | |
Active sitei | 201 | By similarity | 1 |
GO - Molecular functioni
- [acyl-carrier-protein] S-malonyltransferase activity Source: GO_Central
GO - Biological processi
- fatty acid biosynthetic process Source: GO_Central
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism |
Enzyme and pathway databases
BioCyci | BSUB:BSU15900-MONOMER |
UniPathwayi | UPA00094 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:fabD Synonyms:ylpE Ordered Locus Names:BSU15900 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000194210 | 1 – 317 | Malonyl CoA-acyl carrier protein transacylaseAdd BLAST | 317 |
Proteomic databases
jPOSTi | P71019 |
PaxDbi | P71019 |
Interactioni
Protein-protein interaction databases
IntActi | P71019, 1 interactor |
MINTi | P71019 |
STRINGi | 224308.BSU15900 |
Family & Domainsi
Sequence similaritiesi
Belongs to the FabD family.Curated
Phylogenomic databases
eggNOGi | COG0331, Bacteria |
InParanoidi | P71019 |
OMAi | AANYNCP |
PhylomeDBi | P71019 |
Family and domain databases
Gene3Di | 3.40.366.10, 1 hit |
InterProi | View protein in InterPro IPR001227, Ac_transferase_dom_sf IPR014043, Acyl_transferase IPR016035, Acyl_Trfase/lysoPLipase IPR024925, Malonyl_CoA-ACP_transAc IPR004410, Malonyl_CoA-ACP_transAc_FabD IPR016036, Malonyl_transacylase_ACP-bd |
Pfami | View protein in Pfam PF00698, Acyl_transf_1, 1 hit |
PIRSFi | PIRSF000446, Mct, 1 hit |
SMARTi | View protein in SMART SM00827, PKS_AT, 1 hit |
SUPFAMi | SSF52151, SSF52151, 1 hit SSF55048, SSF55048, 1 hit |
TIGRFAMsi | TIGR00128, fabD, 1 hit |
i Sequence
Sequence statusi: Complete.
P71019-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKIAFLFPG QGSQFIGMGK ELYEQVPAAK RLFDEADETL ETKLSSLIFE
60 70 80 90 100
GDAEELTLTY NAQPALLTTS IAVLEKFKES GITPDFTAGH SLGEYSALVA
110 120 130 140 150
AGALSFKDAV YTVRKRGEFM NEAVPAGEGA MAAILGMDAE ALKQVTDKVT
160 170 180 190 200
EEGNLVQLAN LNCPGQIVIS GTAKGVELAS ELAKENGAKR AIPLEVSGPF
210 220 230 240 250
HSELMKPAAE KLKEVLDACD IKDADVPVIS NVSADVMTEK ADIKEKLIEQ
260 270 280 290 300
LYSPVRFEES INKLIAEGVT TFIEIGPGKV LSGLVKKVNR RLKTIAVSDP
310
ETIELAIQTL KEENDNA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 124 – 131 | VPAGEGAM → GCRLAKEQW (PubMed:8759840).Curated | 8 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U59433 Genomic DNA Translation: AAC44306.1 Y13937 Genomic DNA Translation: CAA74249.1 AL009126 Genomic DNA Translation: CAB13463.1 |
PIRi | H69620 |
RefSeqi | NP_389472.1, NC_000964.3 WP_003245314.1, NZ_JNCM01000035.1 |
Genome annotation databases
EnsemblBacteriai | CAB13463; CAB13463; BSU_15900 |
GeneIDi | 938488 |
KEGGi | bsu:BSU15900 |
PATRICi | fig|224308.179.peg.1730 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U59433 Genomic DNA Translation: AAC44306.1 Y13937 Genomic DNA Translation: CAA74249.1 AL009126 Genomic DNA Translation: CAB13463.1 |
PIRi | H69620 |
RefSeqi | NP_389472.1, NC_000964.3 WP_003245314.1, NZ_JNCM01000035.1 |
3D structure databases
AlphaFoldDBi | P71019 |
SMRi | P71019 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | P71019, 1 interactor |
MINTi | P71019 |
STRINGi | 224308.BSU15900 |
Proteomic databases
jPOSTi | P71019 |
PaxDbi | P71019 |
Genome annotation databases
EnsemblBacteriai | CAB13463; CAB13463; BSU_15900 |
GeneIDi | 938488 |
KEGGi | bsu:BSU15900 |
PATRICi | fig|224308.179.peg.1730 |
Phylogenomic databases
eggNOGi | COG0331, Bacteria |
InParanoidi | P71019 |
OMAi | AANYNCP |
PhylomeDBi | P71019 |
Enzyme and pathway databases
UniPathwayi | UPA00094 |
BioCyci | BSUB:BSU15900-MONOMER |
Family and domain databases
Gene3Di | 3.40.366.10, 1 hit |
InterProi | View protein in InterPro IPR001227, Ac_transferase_dom_sf IPR014043, Acyl_transferase IPR016035, Acyl_Trfase/lysoPLipase IPR024925, Malonyl_CoA-ACP_transAc IPR004410, Malonyl_CoA-ACP_transAc_FabD IPR016036, Malonyl_transacylase_ACP-bd |
Pfami | View protein in Pfam PF00698, Acyl_transf_1, 1 hit |
PIRSFi | PIRSF000446, Mct, 1 hit |
SMARTi | View protein in SMART SM00827, PKS_AT, 1 hit |
SUPFAMi | SSF52151, SSF52151, 1 hit SSF55048, SSF55048, 1 hit |
TIGRFAMsi | TIGR00128, fabD, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | FABD_BACSU | |
Accessioni | P71019Primary (citable) accession number: P71019 Secondary accession number(s): O34463 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | May 30, 2000 | |
Last modified: | May 25, 2022 | |
This is version 128 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families