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UniProtKB - P70698 (PYRG1_MOUSE)

Entry version 157 (02 Dec 2020)
Sequence version 2 (25 Jul 2006)
Previous versions | rss
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Protein

CTP synthase 1

Gene

Ctps1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Activated by GTP and inhibited by CTP.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: CTP biosynthesis via de novo pathway

This protein is involved in step 2 of the subpathway that synthesizes CTP from UDP.By similarity
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. CTP synthase 2 (Ctps2), CTP synthase 1 (Ctps1), CTP synthase (glutamine hydrolyzing) (Ctps2)
This subpathway is part of the pathway CTP biosynthesis via de novo pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CTP from UDP, the pathway CTP biosynthesis via de novo pathway and in Pyrimidine metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei399For GATase activityBy similarity1
Active sitei526For GATase activityBy similarity1
Active sitei528For GATase activityBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigase
Biological processImmunity, Pyrimidine biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		6.3.4.2, 3474

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-499943, Interconversion of nucleotide di- and triphosphates

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00159;UER00277

Protein family/group databases

MEROPS protease database

More...MEROPSi		C26.A36

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CTP synthase 1Curated (EC:6.3.4.2By similarity)
Alternative name(s):
CTP synthetase 1
UTP--ammonia ligase 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ctps1
Synonyms:CtpsImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1858304, Ctps

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001382761 – 591CTP synthase 1Add BLAST591

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei100N6-acetyllysineBy similarity1
Modified residuei562PhosphoserineBy similarity1
Modified residuei568PhosphoserineBy similarity1
Modified residuei571PhosphoserineBy similarity1
Modified residuei573PhosphoserineBy similarity1
Modified residuei574PhosphoserineCombined sources1
Modified residuei575PhosphoserineCombined sources1
Modified residuei578PhosphoserineCombined sources1
Modified residuei587PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P70698

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P70698

MaxQB - The MaxQuant DataBase

More...MaxQBi		P70698

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P70698

PeptideAtlas

More...PeptideAtlasi		P70698

PRoteomics IDEntifications database

More...PRIDEi		P70698

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P70698

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P70698

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P70698

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000028633, Expressed in secondary oocyte and 321 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P70698, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		206180, 67 interactors

Protein interaction database and analysis system

More...IntActi		P70698, 3 interactors

Molecular INTeraction database

More...MINTi		P70698

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000030381

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P70698, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P70698

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini300 – 554Glutamine amidotransferase type-1Add BLAST255

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CTP synthase family.Curated

Keywords - Domaini

Glutamine amidotransferase

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2387, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00910000144179

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_011675_5_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P70698

Identification of Orthologs from Complete Genome Data

More...OMAi		EFNNAYR

Database of Orthologous Groups

More...OrthoDBi		810128at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P70698

TreeFam database of animal gene trees

More...TreeFami		TF300379

Family and domain databases

Conserved Domains Database

More...CDDi		cd01746, GATase1_CTP_Synthase, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.880, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_01227, PyrG, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029062, Class_I_gatase-like
IPR004468, CTP_synthase
IPR017456, CTP_synthase_N
IPR017926, GATASE
IPR033828, GATase1_CTP_Synthase
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...PANTHERi		PTHR11550, PTHR11550, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF06418, CTP_synth_N, 1 hit
PF00117, GATase, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52317, SSF52317, 1 hit
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00337, PyrG, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51273, GATASE_TYPE_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P70698-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKYILVTGGV ISGIGKGVIA SSVGTILKSC GLHVTSIKID PYINIDAGTF 
        60         70         80         90        100
SPYEHGEVFV LDDGGEVDLD LGNYERFLDI RLTKDNNLTT GKIYQYVINK 
       110        120        130        140        150
ERKGDYLGKT VQVVPHITDA IQEWVMRQAL IPVDEDGLEP QVCVIELGGT 
       160        170        180        190        200
VGDIESMPFI EAFRQFQFKV KRENFCNIHV SLVPQPSSTG EQKTKPTQNS 
       210        220        230        240        250
VRELRGLGLS PDLVVCRCSN PLDTSVKEKI SMFCHVEPEQ VICVHDVSSI 
       260        270        280        290        300
YRVPLLLEEQ GVVDYFLRRL DLPIERQSRK MLMKWKEMAD RYDRLLETCS 
       310        320        330        340        350
IALVGKYTKF SDSYASVIKA LEHSALAINH KLEIKYIDST DLEPSTLQEE 
       360        370        380        390        400
PVRYHEAWQK LCSAHGVLVP GGFGVRGTEG KIQAIAWARK QKKPFLGVCL 
       410        420        430        440        450
GMQLAVVEFS RNVLGWQDAN STEFDPKTSH PVVIDMPEHN PGQMGGTMRL 
       460        470        480        490        500
GKRRTLFQTK NSVMRKLYGD TDYLEERHRH RFEVNPVLKK CLEEQGLKFV 
       510        520        530        540        550
GQDVEGERME IVELEDHPFF VGVQYHPEFL SRPIKPSPPY FGLLLASVGR 
       560        570        580        590 
LPHYLQKGCR LSPRDTYSDR SGSSSPDSEI TELKFPSISQ D
Length:591
Mass (Da):66,682
Last modified:July 25, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i81083429870BF0DE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti37I → F in AAB06942 (Ref. 1) Curated1
Sequence conflicti308T → P in AAB06942 (Ref. 1) Curated1
Sequence conflicti388A → S in AAB06942 (Ref. 1) Curated1
Sequence conflicti402M → I in AAB06942 (Ref. 1) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U49350 mRNA Translation: AAB06942.1
AK148259 mRNA Translation: BAE28443.1
BC006698 mRNA Translation: AAH06698.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS18591.1

NCBI Reference Sequences

More...RefSeqi		NP_058028.2, NM_016748.2
XP_006503288.1, XM_006503225.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000030381; ENSMUSP00000030381; ENSMUSG00000028633

Database of genes from NCBI RefSeq genomes

More...GeneIDi		51797

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:51797

UCSC genome browser

More...UCSCi		uc008unj.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U49350 mRNA Translation: AAB06942.1
AK148259 mRNA Translation: BAE28443.1
BC006698 mRNA Translation: AAH06698.1
CCDSiCCDS18591.1
RefSeqiNP_058028.2, NM_016748.2
XP_006503288.1, XM_006503225.3

3D structure databases

SMRiP70698
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi206180, 67 interactors
IntActiP70698, 3 interactors
MINTiP70698
STRINGi10090.ENSMUSP00000030381

Protein family/group databases

MEROPSiC26.A36

PTM databases

iPTMnetiP70698
PhosphoSitePlusiP70698
SwissPalmiP70698

Proteomic databases

EPDiP70698
jPOSTiP70698
MaxQBiP70698
PaxDbiP70698
PeptideAtlasiP70698
PRIDEiP70698

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		4476, 165 antibodies

Genome annotation databases

EnsembliENSMUST00000030381; ENSMUSP00000030381; ENSMUSG00000028633
GeneIDi51797
KEGGimmu:51797
UCSCiuc008unj.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		51797
MGIiMGI:1858304, Ctps

Phylogenomic databases

eggNOGiKOG2387, Eukaryota
GeneTreeiENSGT00910000144179
HOGENOMiCLU_011675_5_0_1
InParanoidiP70698
OMAiEFNNAYR
OrthoDBi810128at2759
PhylomeDBiP70698
TreeFamiTF300379

Enzyme and pathway databases

UniPathwayiUPA00159;UER00277
BRENDAi6.3.4.2, 3474
ReactomeiR-MMU-499943, Interconversion of nucleotide di- and triphosphates

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		51797, 7 hits in 22 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Ctps, mouse

Protein Ontology

More...PROi		PR:P70698
RNActiP70698, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000028633, Expressed in secondary oocyte and 321 other tissues
GenevisibleiP70698, MM

Family and domain databases

CDDicd01746, GATase1_CTP_Synthase, 1 hit
Gene3Di3.40.50.880, 1 hit
HAMAPiMF_01227, PyrG, 1 hit
InterProiView protein in InterPro
IPR029062, Class_I_gatase-like
IPR004468, CTP_synthase
IPR017456, CTP_synthase_N
IPR017926, GATASE
IPR033828, GATase1_CTP_Synthase
IPR027417, P-loop_NTPase
PANTHERiPTHR11550, PTHR11550, 1 hit
PfamiView protein in Pfam
PF06418, CTP_synth_N, 1 hit
PF00117, GATase, 1 hit
SUPFAMiSSF52317, SSF52317, 1 hit
SSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR00337, PyrG, 1 hit
PROSITEiView protein in PROSITE
PS51273, GATASE_TYPE_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPYRG1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P70698
Secondary accession number(s): Q922Y4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 25, 2006
Last modified: December 2, 2020
This is version 157 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families
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