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1 to 25 of 81  Show
  1. 1
    "A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel."
    Isomoto S., Kondo C., Yamada M., Matsumoto S., Higashiguchi O., Horio Y., Matsuzawa Y., Kurachi Y.
    J. Biol. Chem. 271:24321-24324(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 24 other entries.

  2. 2
    Faure C., Partiseti M., Gouhier C., Graham D.
    Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats."
    Tokuyama Y., Fan Z., Furuta H., Makielski J.C., Polonsky K.S., Bell G.I., Yano H.
    Biochem. Biophys. Res. Commun. 220:532-538(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Strain: Wistar.
    Tissue: Pancreatic islet.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    Wada Y., Takao K., Nishi M., Takeshima H., Imai K., Yamashita T., Kokubun S., Yoshii M., Nukada T.
    Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Strain: Wistar.
    Tissue: Heart ventricle.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    Cao K., Wang R.
    Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "Localization of pore-forming subunit of the ATP-sensitive K(+)-channel, Kir6.2, in rat brain neurons and glial cells."
    Zhou M., Tanaka O., Suzuki M., Sekiguchi M., Takata K., Kawahara K., Abe H.
    Brain Res. Mol. Brain Res. 101:23-32(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: Kir6.2 was found in most rat brain neuronal populations. Both oligodendrocytes and astrocytes contain Kir6.2. It was found in the endoplasmic reticulum Golgi apparatus and cell membranes of glia and neurons.Imported.
    Source: GeneRIF:83535.
  7. 7
    "Molecular basis of ATP-sensitive K+ channels in rat vascular smooth muscles."
    Cao K., Tang G., Hu D., Wang R.
    Biochem. Biophys. Res. Commun. 296:463-469(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: Results report the expression of four K(ATP) subunits in vascular tissues unmasking the diversity of native K(ATP) channels in vascular SMCs.Imported.
    Source: GeneRIF:83535.

    This publication is mapped to 2 other entries.

  8. 8
    "Distribution of Kir6.0 and SUR2 ATP-sensitive potassium channel subunits in isolated ventricular myocytes."
    Singh H., Hudman D., Lawrence C.L., Rainbow R.D., Lodwick D., Norman R.I.
    J. Mol. Cell. Cardiol. 35:445-459(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:69247.
  9. 9
    "ATP-sensitive potassium channels mediate hyperosmotic stimulation of NKCC in slow-twitch muscle."
    Gosmanov A.R., Fan Z., Mi X., Schneider E.G., Thomason D.B.
    Am. J. Physiol., Cell Physiol. 286:C586-95(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: activation of KATP channels in slow-twitch muscle is necessary for activation of the NKCC and cell volume restoration in hyperosmotic conditions.Imported.
    Source: GeneRIF:83535.
  10. 10
    "Proximal C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channels."
    Rainbow R.D., James M., Hudman D., Al Johi M., Singh H., Watson P.J., Ashmole I., Davies N.W., Lodwick D., Norman R.I.
    Biochem. J. 379:173-181(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: There is a direct interaction between Kir6.2 and a 65-amino-acid section of the cytoplasmic C-terminal region of rSUR2A between residues 1294 and 1358.Imported.
    Source: RGD:69247, GeneRIF:83535.

    This publication is mapped to 3 other entries.

  11. 11
    "Pore loop-mutated rat KIR6.1 and KIR6.2 suppress KATP current in rat cardiomyocytes."
    van Bever L., Poitry S., Faure C., Norman R.I., Roatti A., Baertschi A.J.
    Am. J. Physiol. Heart Circ. Physiol. 287:H850-9(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: KIR6.1 may associate with KIR6.2 to form heterotetrameric pores of native K(ATP) channels in cardiomyocytes.Imported.
    Source: GeneRIF:83535.
  12. 12
    "Disruption of glucose sensing and insulin secretion by ribozyme Kir6.2-gene targeting in insulin-secreting cells."
    Li L., Rojas A., Wu J., Jiang C.
    Endocrinology 145:4408-4414(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: KATP channels play an important role in glucose sensing and insulin secretion and ribozyme Kir6.2-gene targeting is an effective approach for selective inhibition of functional expression of KATP channels.Imported.
    Source: GeneRIF:83535.
  13. 13
    "Regulation of ATP-sensitive potassium channel subunit Kir6.2 expression in rat intestinal insulin-producing progenitor cells."
    Hashimoto T., Nakamura T., Maegawa H., Nishio Y., Egawa K., Kashiwagi A.
    J. Biol. Chem. 280:1893-1900(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: expression of Kir6.2 in the rat intestine is moderated by Isl-1Imported.
    Source: GeneRIF:83535.
  14. 14
    "Two SUR1-specific histidine residues mandatory for zinc-induced activation of the rat KATP channel."
    Bancila V., Cens T., Monnier D., Chanson F., Faure C., Dunant Y., Bloc A.
    J. Biol. Chem. 280:8793-8799(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: Zinc activated KATP in cells co-expressing rat Kir6.2 and SUR1 subunits.Imported.
    Source: GeneRIF:83535.

    This publication is mapped to 6 other entries.

  15. 15
    "Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature."
    Morrissey A., Rosner E., Lanning J., Parachuru L., Dhar Chowdhury P., Han S., Lopez G., Tong X., Yoshida H., Nakamura T.Y., Artman M., Giblin J.P., Tinker A., Coetzee W.A.
    BMC Physiol. 5:1-1(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:69247.

    This publication is mapped to 6 other entries.

  16. 16
    "Pore-forming subunits of K-ATP channels, Kir6.1 and Kir6.2, display prominent differences in regional and cellular distribution in the rat brain."
    Thomzig A., Laube G., Pruss H., Veh R.W.
    J. Comp. Neurol. 484:313-330(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: Kir6.2 to be widely expressed in all brain regions suggesting that the Kir6.2 subunit forms the pore of the K-ATP channels in most neuronsImported.
    Source: GeneRIF:83535.
  17. 17
    "The C42R mutation in the Kir6.2 (KCNJ11) gene as a cause of transient neonatal diabetes, childhood diabetes, or later-onset, apparently type 2 diabetes mellitus."
    Yorifuji T., Nagashima K., Kurokawa K., Kawai M., Oishi M., Akazawa Y., Hosokawa M., Yamada Y., Inagaki N., Nakahata T.
    J. Clin. Endocrinol. Metab. 90:3174-3178(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: Mutations in this gene should be taken into consideration for not only permanent neonatal diabetes but also other forms of diabetes with milder phenotypes and later onset.Imported.
    Source: GeneRIF:83535.
  18. 18
    "Studies of ATP-sensitive potassium channels on 6-hydroxydopamine and haloperidol rat models of Parkinson's disease: implications for treating Parkinson's disease?"
    Wang S., Hu L.F., Yang Y., Ding J.H., Hu G.
    Neuropharmacology 48:984-992(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Source: RGD:69247.

    This publication is mapped to 6 other entries.

  19. 19
    "Iptakalim, opener of K(ATP), reverses the enhanced expression of genes encoding K(ATP) subunits in spontaneously hypertensive rats."
    Gao M., Xue H., Wang Y., Wang H.
    Life Sci. 77:2743-2751(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Expression.
    Source: RGD:69247.

    This publication is mapped to 3 other entries.

  20. 20
    "ATP-sensitive K+-channel subunits on the mitochondria and endoplasmic reticulum of rat cardiomyocytes."
    Zhou M., Tanaka O., Sekiguchi M., He H.J., Yasuoka Y., Itoh H., Kawahara K., Abe H.
    J. Histochem. Cytochem. 53:1491-1500(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:69247.

    This publication is mapped to 1 other entry.

  21. 21
    "KATP channel conductance of descending vasa recta pericytes."
    Cao C., Lee-Kwon W., Silldorff E.P., Pallone T.L.
    Am. J. Physiol. Renal Physiol. 289:F1235-45(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:69247.

    This publication is mapped to 1 other entry.

  22. 22
    "Subunit composition of ATP-sensitive potassium channels in mitochondria of rat hearts."
    Cuong D.V., Kim N., Joo H., Youm J.B., Chung J.Y., Lee Y., Park W.S., Kim E., Park Y.S., Han J.
    Mitochondrion 5:121-133(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:69247.

    This publication is mapped to 4 other entries.

  23. 23
    "Mechanism of rat mesenteric arterial KATP channel activation by 14,15-epoxyeicosatrienoic acid."
    Ye D., Zhou W., Lu T., Jagadeesh S.G., Falck J.R., Lee H.C.
    Am. J. Physiol. Heart Circ. Physiol. 290:H1326-36(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: These results suggest that 14 15-EET activates vascular K(ATP) channels through ADP-ribosylation of G(s)alpha.Imported.
    Source: GeneRIF:83535.
  24. 24
    "Kir6.2 mutations associated with neonatal diabetes reduce expression of ATP-sensitive K+ channels: implications in disease mechanism and sulfonylurea therapy."
    Lin C.W., Lin Y.W., Yan F.F., Casey J., Kochhar M., Pratt E.B., Shyng S.L.
    Diabetes 55:1738-1746(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: findings show that PNDM mutations including Q52R V59G V59M R201C R201H and I296L not only reduce channel ATP sensitivity but also impair channel expression at the cell surface to varying degreesImported.
    Source: GeneRIF:83535.
  25. 25
    "Sulfonylureas correct trafficking defects of disease-causing ATP-sensitive potassium channels by binding to the channel complex."
    Yan F.F., Casey J., Shyng S.L.
    J. Biol. Chem. 281:33403-33413(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: sulfonylureas also reverse trafficking defects caused by neonatal diabetes-associated Kir6.2 mutations in a way that is dependent on intact sulfonylurea binding sites in sulfonylurea receptor 1 further support this notionImported.
    Source: GeneRIF:83535.
1 to 25 of 81  Show

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