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Entry version 166 (07 Apr 2021)
Sequence version 3 (27 Jul 2011)
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Protein

SPARC-like protein 1

Gene

Sparcl1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi621 – 632PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalcium, Metal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-381426, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-MMU-8957275, Post-translational protein phosphorylation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SPARC-like protein 1
Alternative name(s):
Extracellular matrix protein 2
Matrix glycoprotein Sc1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sparcl1
Synonyms:Ecm2, Sc1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:108110, Sparcl1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 16Sequence analysisAdd BLAST16
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002031317 – 650SPARC-like protein 1Add BLAST634

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei70PhosphoserineBy similarity1
Modified residuei78PhosphoserineBy similarity1
Modified residuei86PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi148N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei155PhosphoserineBy similarity1
Modified residuei163PhosphoserineBy similarity1
Glycosylationi168N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei272PhosphoserineBy similarity1
Modified residuei353PhosphoserineCombined sources1
Modified residuei406PhosphoserineCombined sources1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi419 ↔ 430PROSITE-ProRule annotation
Disulfide bondi424 ↔ 440PROSITE-ProRule annotation
Disulfide bondi442 ↔ 476PROSITE-ProRule annotation
Disulfide bondi448 ↔ 469PROSITE-ProRule annotation
Disulfide bondi458 ↔ 495PROSITE-ProRule annotation
Glycosylationi462N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi501 ↔ 612PROSITE-ProRule annotation
Disulfide bondi620 ↔ 636PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
non-CPTAC-3616

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P70663

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P70663

PeptideAtlas

More...
PeptideAtlasi
P70663

PRoteomics IDEntifications database

More...
PRIDEi
P70663

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
263328

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2737, 9 N-Linked glycans (2 sites)

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
P70663, 3 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P70663

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P70663

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highest expression in brain. Moderate levels in heart, adrenal gland, epididymis and lung. Low levels in kidney, eye, liver, spleen, submandibular gland and testis.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000029309, Expressed in superior colliculus and 291 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P70663, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
199367, 1 interactor

Protein interaction database and analysis system

More...
IntActi
P70663, 5 interactors

Molecular INTeraction database

More...
MINTi
P70663

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000031249

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P70663, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P70663

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini418 – 440Follistatin-likeAdd BLAST23
Domaini436 – 497Kazal-likePROSITE-ProRule annotationAdd BLAST62
Domaini608 – 643EF-handPROSITE-ProRule annotationAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi192 – 277Glu-richAdd BLAST86
Compositional biasi192 – 209Poly-GluAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SPARC family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4004, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00510000046787

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_026297_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P70663

Identification of Orthologs from Complete Genome Data

More...
OMAi
CKRGHVC

Database of Orthologous Groups

More...
OrthoDBi
1528521at2759

TreeFam database of animal gene trees

More...
TreeFami
TF319356

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR003645, Fol_N
IPR015369, Follistatin/Osteonectin_EGF
IPR002350, Kazal_dom
IPR036058, Kazal_dom_sf
IPR001999, Osteonectin_CS
IPR016359, SPARC-like_p1
IPR019577, SPARC/Testican_Ca-bd-dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09289, FOLN, 1 hit
PF00050, Kazal_1, 1 hit
PF10591, SPARC_Ca_bdg, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002574, SPARC-like_p1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00274, FOLN, 1 hit
SM00280, KAZAL, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF100895, SSF100895, 1 hit
SSF47473, SSF47473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 1 hit
PS51465, KAZAL_2, 1 hit
PS00612, OSTEONECTIN_1, 1 hit
PS00613, OSTEONECTIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P70663-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKAVLLLLCA LGTAVAIPTS TRFLSDHSNP TTATLVTPED ATVPIAGVEA
60 70 80 90 100
TADIENHPSD KAEKPSALNS EEETHEQSTE QDKTYSFEVD LKDEEDGDGD
110 120 130 140 150
LSVDPTEGTL TLDLQEGTSE PQQKSLPENG DFPATVSTSY VDPNQRANIT
160 170 180 190 200
KGKESQEQPV SDSHQQPNES SKQTQDLKAE ESQTQDPDIP NEEEEEEEDE
210 220 230 240 250
EEEEEEEPED IGAPSDNQEE GKEPLEEQPT SKWEGNREQS DDTLEESSQP
260 270 280 290 300
TQISKTEKHQ SEQGNQGQES DSEAEGEDKA AGSKEHIPHT EQQDQEGKAG
310 320 330 340 350
LEAIGNQKDT DEKAVSTEPT DAAVVPRSHG GAGDNGGGDD SKHGAGDDYF
360 370 380 390 400
IPSQEFLEAE RMHSLSYYLK YGGGEETTTG ESENRREAAD NQEAKKAESS
410 420 430 440 450
PNAEPSDEGN SREHSAGSCT NFQCKRGHIC KTDPQGKPHC VCQDPETCPP
460 470 480 490 500
AKILDQACGT DNQTYASSCH LFATKCRLEG TKKGHQLQLD YFGACKSIPA
510 520 530 540 550
CTDFEVAQFP LRMRDWLKNI LMQLYEPNPK HGGYLNEKQR SKVKKIYLDE
560 570 580 590 600
KRLLAGDHPI ELLLRDFKKN YHMYVYPVHW QFNELDQHPA DRILTHSELA
610 620 630 640 650
PLRASLVPME HCITRFFEEC DPNKDKHITL KEWGHCFGIK EEDIDENLLF
Length:650
Mass (Da):72,287
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8E2CA0145DE3E66E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JFH7A0A0G2JFH7_MOUSE
SPARC-like protein 1
Sparcl1
239Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti25S → F in AAC53172 (PubMed:9199668).Curated1
Sequence conflicti59S → N in AAB06444 (PubMed:8938431).Curated1
Sequence conflicti59S → N in AAB08451 (PubMed:8938431).Curated1
Sequence conflicti59S → N in AAC53172 (PubMed:9199668).Curated1
Sequence conflicti59S → N in AAH03759 (PubMed:15489334).Curated1
Sequence conflicti199D → E in AAB06444 (PubMed:8938431).Curated1
Sequence conflicti199D → E in AAB08451 (PubMed:8938431).Curated1
Sequence conflicti281A → S in AAB06444 (PubMed:8938431).Curated1
Sequence conflicti281A → S in AAB08451 (PubMed:8938431).Curated1
Sequence conflicti385R → Q in AAB06444 (PubMed:8938431).Curated1
Sequence conflicti385R → Q in AAB08451 (PubMed:8938431).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U66166 U66165 Genomic DNA Translation: AAB06444.1
U77330 mRNA Translation: AAC53172.1
U64827 mRNA Translation: AAB08451.1
AL714024 Genomic DNA No translation available.
BC003759 mRNA Translation: AAH03759.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS19483.1

NCBI Reference Sequences

More...
RefSeqi
NP_034227.3, NM_010097.4
XP_006534831.1, XM_006534768.1
XP_017176145.1, XM_017320656.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000031249; ENSMUSP00000031249; ENSMUSG00000029309

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
13602

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:13602

UCSC genome browser

More...
UCSCi
uc008ykb.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66166 U66165 Genomic DNA Translation: AAB06444.1
U77330 mRNA Translation: AAC53172.1
U64827 mRNA Translation: AAB08451.1
AL714024 Genomic DNA No translation available.
BC003759 mRNA Translation: AAH03759.1
CCDSiCCDS19483.1
RefSeqiNP_034227.3, NM_010097.4
XP_006534831.1, XM_006534768.1
XP_017176145.1, XM_017320656.1

3D structure databases

SMRiP70663
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi199367, 1 interactor
IntActiP70663, 5 interactors
MINTiP70663
STRINGi10090.ENSMUSP00000031249

PTM databases

GlyConnecti2737, 9 N-Linked glycans (2 sites)
GlyGeniP70663, 3 sites
iPTMnetiP70663
PhosphoSitePlusiP70663

Proteomic databases

CPTACinon-CPTAC-3616
MaxQBiP70663
PaxDbiP70663
PeptideAtlasiP70663
PRIDEiP70663
ProteomicsDBi263328

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
25430, 278 antibodies

Genome annotation databases

EnsembliENSMUST00000031249; ENSMUSP00000031249; ENSMUSG00000029309
GeneIDi13602
KEGGimmu:13602
UCSCiuc008ykb.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8404
MGIiMGI:108110, Sparcl1

Phylogenomic databases

eggNOGiKOG4004, Eukaryota
GeneTreeiENSGT00510000046787
HOGENOMiCLU_026297_0_1_1
InParanoidiP70663
OMAiCKRGHVC
OrthoDBi1528521at2759
TreeFamiTF319356

Enzyme and pathway databases

ReactomeiR-MMU-381426, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-MMU-8957275, Post-translational protein phosphorylation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
13602, 2 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Sparcl1, mouse

Protein Ontology

More...
PROi
PR:P70663
RNActiP70663, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000029309, Expressed in superior colliculus and 291 other tissues
GenevisibleiP70663, MM

Family and domain databases

InterProiView protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR003645, Fol_N
IPR015369, Follistatin/Osteonectin_EGF
IPR002350, Kazal_dom
IPR036058, Kazal_dom_sf
IPR001999, Osteonectin_CS
IPR016359, SPARC-like_p1
IPR019577, SPARC/Testican_Ca-bd-dom
PfamiView protein in Pfam
PF09289, FOLN, 1 hit
PF00050, Kazal_1, 1 hit
PF10591, SPARC_Ca_bdg, 1 hit
PIRSFiPIRSF002574, SPARC-like_p1, 1 hit
SMARTiView protein in SMART
SM00274, FOLN, 1 hit
SM00280, KAZAL, 1 hit
SUPFAMiSSF100895, SSF100895, 1 hit
SSF47473, SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 1 hit
PS51465, KAZAL_2, 1 hit
PS00612, OSTEONECTIN_1, 1 hit
PS00613, OSTEONECTIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPRL1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P70663
Secondary accession number(s): E9QPH2, P97810, Q99L82
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: July 27, 2011
Last modified: April 7, 2021
This is version 166 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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