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UniProtKB - P70423 (CTR3_MOUSE)

Entry version 156 (16 Oct 2019)
Sequence version 1 (01 Feb 1997)
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Protein

Cationic amino acid transporter 3

Gene

Slc7a3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-352230 Amino acid transport across the plasma membrane

Protein family/group databases

Transport Classification Database

More...TCDBi		2.A.3.3.5 the amino acid-polyamine-organocation (apc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cationic amino acid transporter 3
Short name:
CAT-3
Short name:
CAT3
Alternative name(s):
Cationic amino acid transporter y+
Solute carrier family 7 member 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Slc7a3
Synonyms:Atrc3, Cat3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1100521 Slc7a3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 36CytoplasmicSequence analysisAdd BLAST36
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei37 – 57Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini58 – 61ExtracellularSequence analysis4
Transmembranei62 – 82Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini83 – 107CytoplasmicSequence analysisAdd BLAST25
Transmembranei108 – 128Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini129 – 162ExtracellularSequence analysisAdd BLAST34
Transmembranei163 – 183Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini184 – 191CytoplasmicSequence analysis8
Transmembranei192 – 212Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini213 – 244ExtracellularSequence analysisAdd BLAST32
Transmembranei245 – 265Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini266 – 285CytoplasmicSequence analysisAdd BLAST20
Transmembranei286 – 306Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini307 – 335ExtracellularSequence analysisAdd BLAST29
Transmembranei336 – 356Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini357 – 380CytoplasmicSequence analysisAdd BLAST24
Transmembranei381 – 401Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini402 – 406ExtracellularSequence analysis5
Transmembranei407 – 427Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini428 – 474CytoplasmicSequence analysisAdd BLAST47
Transmembranei475 – 495Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini496 – 506ExtracellularSequence analysisAdd BLAST11
Transmembranei507 – 527Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini528 – 539CytoplasmicSequence analysisAdd BLAST12
Transmembranei540 – 560Helical; Name=13Sequence analysisAdd BLAST21
Topological domaini561 – 568ExtracellularSequence analysis8
Transmembranei569 – 589Helical; Name=14Sequence analysisAdd BLAST21
Topological domaini590 – 618CytoplasmicSequence analysisAdd BLAST29

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000542671 – 618Cationic amino acid transporter 3Add BLAST618

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi232N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei605PhosphothreonineBy similarity1
Modified residuei617PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P70423

MaxQB - The MaxQuant DataBase

More...MaxQBi		P70423

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P70423

PeptideAtlas

More...PeptideAtlasi		P70423

PRoteomics IDEntifications database

More...PRIDEi		P70423

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P70423

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P70423

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P70423

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in adult brain and in a wide variety of embryonic tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000031297 Expressed in 117 organ(s), highest expression level in hypothalamus

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P70423 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		198277, 1 interactor

Protein interaction database and analysis system

More...IntActi		P70423, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000098914

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1286 Eukaryota
COG0531 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154651

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000250623

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P70423

KEGG Orthology (KO)

More...KOi		K13865

Identification of Orthologs from Complete Genome Data

More...OMAi		HFLARIH

Database of Orthologous Groups

More...OrthoDBi		439017at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P70423

TreeFam database of animal gene trees

More...TreeFami		TF315212

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002293 AA/rel_permease1
IPR015606 CAT3
IPR004755 Cat_AA_permease
IPR029485 CAT_C

The PANTHER Classification System

More...PANTHERi		PTHR43243:SF20 PTHR43243:SF20, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13520 AA_permease_2, 1 hit
PF13906 AA_permease_C, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF006060 AA_transporter, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00906 2A0303, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P70423-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLWQALRRFG QKLVRRRVLE LGMGETRLAR CLSTLDLVAL GVGSTLGAGV 
        60         70         80         90        100
YVLAGEVAKD KAGPSIVICF LVAALSSVLA GLCYAEFGAR VPGSGSAYLY 
       110        120        130        140        150
SYVTVGELWA FTTGWNLILS YVIGTASVAR AWSSAFDNLI GNHISRTLKG 
       160        170        180        190        200
TILLKMPHVL AEYPDFFALA LVLLLTGLLV LGASKSALVT KVFTGMNLLV 
       210        220        230        240        250
LSFVIISGFI KGELRNWKLT KEDYCLTMSE SNGTCSLDSM GSGGFMPFGL 
       260        270        280        290        300
EGILRGAATC FYAFVGFDCI ATTGEEAQNP QRSIPMGIVI SMFICFLAYF 
       310        320        330        340        350
GVSSALTLMM PYYKLHPESP LPEAFSYVGW EPARYLVAIG SLCALSTSLL 
       360        370        380        390        400
GSMFPMPRVM YSMAEDGLLF RVLAKVHSVT HIPIVATLVS GVIAAFMAFL 
       410        420        430        440        450
FELTDLVDLM SIGTLLAHSL VSICVLILRY QPDQEMKSVE EEMELQEETL 
       460        470        480        490        500
EAEKLTVQAL FCPVNSIPTL LSGRVVYVCS SLLAVLLTVL CLVLTWWTTP 
       510        520        530        540        550
LRSGDPVWVT VVVLILGLIL AISGVIWRQP QNRTPLHFKV PAVPLLPLVS 
       560        570        580        590        600
IFVNVYLMMQ MTAGTWARFG IWMLIGFAIY FGYGIQHSMK EVKNHQTLPK 
       610 
TRAQTIDLDL TTSCVHSI
Length:618
Mass (Da):67,460
Last modified:February 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i605AFC255A8251DC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U70859 mRNA Translation: AAB09593.1
AK077593 mRNA Translation: BAC36884.1
AL672308 Genomic DNA No translation available.
BC050195 mRNA Translation: AAH50195.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS30309.1

NCBI Reference Sequences

More...RefSeqi		NP_001288769.1, NM_001301840.1
NP_031541.1, NM_007515.3
XP_006527816.1, XM_006527753.2
XP_011245812.1, XM_011247510.1
XP_011245813.1, XM_011247511.1
XP_011245814.1, XM_011247512.1
XP_011245815.1, XM_011247513.1
XP_017173852.1, XM_017318363.1
XP_017173853.1, XM_017318364.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000073927; ENSMUSP00000073582; ENSMUSG00000031297
ENSMUST00000101362; ENSMUSP00000098914; ENSMUSG00000031297
ENSMUST00000113710; ENSMUSP00000109339; ENSMUSG00000031297

Database of genes from NCBI RefSeq genomes

More...GeneIDi		11989

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:11989

UCSC genome browser

More...UCSCi		uc009twt.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70859 mRNA Translation: AAB09593.1
AK077593 mRNA Translation: BAC36884.1
AL672308 Genomic DNA No translation available.
BC050195 mRNA Translation: AAH50195.1
CCDSiCCDS30309.1
RefSeqiNP_001288769.1, NM_001301840.1
NP_031541.1, NM_007515.3
XP_006527816.1, XM_006527753.2
XP_011245812.1, XM_011247510.1
XP_011245813.1, XM_011247511.1
XP_011245814.1, XM_011247512.1
XP_011245815.1, XM_011247513.1
XP_017173852.1, XM_017318363.1
XP_017173853.1, XM_017318364.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi198277, 1 interactor
IntActiP70423, 1 interactor
STRINGi10090.ENSMUSP00000098914

Protein family/group databases

TCDBi2.A.3.3.5 the amino acid-polyamine-organocation (apc) family

PTM databases

iPTMnetiP70423
PhosphoSitePlusiP70423
SwissPalmiP70423

Proteomic databases

EPDiP70423
MaxQBiP70423
PaxDbiP70423
PeptideAtlasiP70423
PRIDEiP70423

Genome annotation databases

EnsembliENSMUST00000073927; ENSMUSP00000073582; ENSMUSG00000031297
ENSMUST00000101362; ENSMUSP00000098914; ENSMUSG00000031297
ENSMUST00000113710; ENSMUSP00000109339; ENSMUSG00000031297
GeneIDi11989
KEGGimmu:11989
UCSCiuc009twt.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		84889
MGIiMGI:1100521 Slc7a3

Phylogenomic databases

eggNOGiKOG1286 Eukaryota
COG0531 LUCA
GeneTreeiENSGT00940000154651
HOGENOMiHOG000250623
InParanoidiP70423
KOiK13865
OMAiHFLARIH
OrthoDBi439017at2759
PhylomeDBiP70423
TreeFamiTF315212

Enzyme and pathway databases

ReactomeiR-MMU-352230 Amino acid transport across the plasma membrane

Miscellaneous databases

Protein Ontology

More...PROi		PR:P70423

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000031297 Expressed in 117 organ(s), highest expression level in hypothalamus
GenevisibleiP70423 MM

Family and domain databases

InterProiView protein in InterPro
IPR002293 AA/rel_permease1
IPR015606 CAT3
IPR004755 Cat_AA_permease
IPR029485 CAT_C
PANTHERiPTHR43243:SF20 PTHR43243:SF20, 1 hit
PfamiView protein in Pfam
PF13520 AA_permease_2, 1 hit
PF13906 AA_permease_C, 1 hit
PIRSFiPIRSF006060 AA_transporter, 1 hit
TIGRFAMsiTIGR00906 2A0303, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCTR3_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P70423
Secondary accession number(s): B1AVE2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: February 1, 1997
Last modified: October 16, 2019
This is version 156 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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