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Entry version 129 (18 Sep 2019)
Sequence version 2 (23 Jan 2007)
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Protein

PTS system glucose-specific EIIA component

Gene

crr

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (PubMed:3129430, PubMed:17158705). The enzyme II complex composed of PtsG and Crr is involved in glucose transport (PubMed:2657735). The non-phosphorylated EIII-Glc is an inhibitor for uptake of certain sugars such as maltose, melibiose, lactose, and glycerol. Phosphorylated EIII-Glc, however, may be an activator for adenylate cyclase. It is an important regulatory protein for cell metabolism (PubMed:789369).1 Publication3 Publications

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+2 PublicationsNote: Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi76Zinc; shared with glycerol kinase1 Publication3 Publications1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei76Important for phospho-donor activity1 Publication1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei91Tele-phosphohistidine intermediate; for EIIA activityPROSITE-ProRule annotation2 Publications2 Publications1
Metal bindingi91Zinc; shared with glycerol kinase1 Publication3 Publications1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processPhosphotransferase system, Sugar transport, Transport
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:CRR-MONOMER
ECOL316407:JW2410-MONOMER
MetaCyc:CRR-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
4.A.1.1.1 the pts glucose-glucoside (glc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PTS system glucose-specific EIIA component1 Publication
Alternative name(s):
EIIA-Glc1 Publication
EIII-Glc1 Publication
Glucose-specific phosphotransferase enzyme IIA component1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:crr1 Publication
Synonyms:gsr, iex, tgs, treD
Ordered Locus Names:b2417, JW2410
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

More...
EcoGenei
EG10165 crr

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

In mutants defective in enzyme I and histidine-containing phosphate carrier protein (HPr), cells lacking this gene are able to grow on the non-PTS compounds such as glycerol, maltose, melibiose, mannose 6-phosphate, and alpha-glycerol phosphate.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi4F → W: Same activity as the wild-type. 1 Publication1
Mutagenesisi76H → Q: Unable to transfer phosphoryl group. 1 Publication1
Mutagenesisi91H → Q: Unable to be phosphorylated by Hpr. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved3 Publications
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001865322 – 169PTS system glucose-specific EIIA componentAdd BLAST168

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei91Phosphohistidine; by HPr1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P69783

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P69783

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P69783

PRoteomics IDEntifications database

More...
PRIDEi
P69783

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
P69783

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P69783

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterodimer with glycerol kinase (glpk).

1 Publication2 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4260572, 36 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1978 Enzyme IIA-maltose transporter complex

Database of interacting proteins

More...
DIPi
DIP-31863N

Protein interaction database and analysis system

More...
IntActi
P69783, 5 interactors

STRING: functional protein association networks

More...
STRINGi
511145.b2417

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1169
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P69783

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P69783

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 143PTS EIIA type-1PROSITE-ProRule annotationAdd BLAST105

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The EIIA domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB domain.PROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105C5Y Bacteria
COG2190 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000224567

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P69783

KEGG Orthology (KO)

More...
KOi
K02777

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P69783

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.70.70.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011055 Dup_hybrid_motif
IPR001127 PTS_EIIA_1_perm

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00358 PTS_EIIA_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51261 SSF51261, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00830 PTBA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51093 PTS_EIIA_TYPE_1, 1 hit
PS00371 PTS_EIIA_TYPE_1_HIS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P69783-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLFDKLKSL VSDDKKDTGT IEIIAPLSGE IVNIEDVPDV VFAEKIVGDG
60 70 80 90 100
IAIKPTGNKM VAPVDGTIGK IFETNHAFSI ESDSGVELFV HFGIDTVELK
110 120 130 140 150
GEGFKRIAEE GQRVKVGDTV IEFDLPLLEE KAKSTLTPVV ISNMDEIKEL
160
IKLSGSVTVG ETPVIRIKK
Length:169
Mass (Da):18,251
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA18020745531215
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti23 – 31Missing in AAC44167 (PubMed:8764513).Curated9

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
J02796 Genomic DNA Translation: AAA24442.1
M21994 Genomic DNA Translation: AAA24386.1
M93578 Genomic DNA Translation: AAA23602.1
M93579 Genomic DNA Translation: AAA23605.1
M93580 Genomic DNA Translation: AAA23603.1
M93581 Genomic DNA Translation: AAA23606.1
M93582 Genomic DNA Translation: AAA23604.1
M93584 Genomic DNA Translation: AAA23610.1
M93587 Genomic DNA Translation: AAA23612.1
M93594 Genomic DNA Translation: AAA23607.1
M93595 Genomic DNA Translation: AAA23608.1
M93596 Genomic DNA Translation: AAA23611.1
M93597 Genomic DNA Translation: AAA23609.1
M93598 Genomic DNA Translation: AAA23613.1
U53700 Genomic DNA Translation: AAC44167.1
U00096 Genomic DNA Translation: AAC75470.1
AP009048 Genomic DNA Translation: BAA16291.1

Protein sequence database of the Protein Information Resource

More...
PIRi
C29785 WQECP3

NCBI Reference Sequences

More...
RefSeqi
NP_416912.1, NC_000913.3
WP_000522247.1, NZ_STEB01000039.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC75470; AAC75470; b2417
BAA16291; BAA16291; BAA16291

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
946880

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW2410
eco:b2417

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1411691.4.peg.4314

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02796 Genomic DNA Translation: AAA24442.1
M21994 Genomic DNA Translation: AAA24386.1
M93578 Genomic DNA Translation: AAA23602.1
M93579 Genomic DNA Translation: AAA23605.1
M93580 Genomic DNA Translation: AAA23603.1
M93581 Genomic DNA Translation: AAA23606.1
M93582 Genomic DNA Translation: AAA23604.1
M93584 Genomic DNA Translation: AAA23610.1
M93587 Genomic DNA Translation: AAA23612.1
M93594 Genomic DNA Translation: AAA23607.1
M93595 Genomic DNA Translation: AAA23608.1
M93596 Genomic DNA Translation: AAA23611.1
M93597 Genomic DNA Translation: AAA23609.1
M93598 Genomic DNA Translation: AAA23613.1
U53700 Genomic DNA Translation: AAC44167.1
U00096 Genomic DNA Translation: AAC75470.1
AP009048 Genomic DNA Translation: BAA16291.1
PIRiC29785 WQECP3
RefSeqiNP_416912.1, NC_000913.3
WP_000522247.1, NZ_STEB01000039.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1F3GX-ray2.10A9-169[»]
1F3ZX-ray1.98A9-169[»]
1GGRNMR-A2-169[»]
1GLAX-ray2.60F2-169[»]
1GLBX-ray2.60F2-169[»]
1GLCX-ray2.65F2-169[»]
1GLDX-ray2.93F2-169[»]
1GLEX-ray2.94F2-169[»]
1O2FNMR-A2-169[»]
2F3GX-ray2.13A/B2-169[»]
2MP0NMR-B2-169[»]
4JBWX-ray3.91M/N/O/P1-169[»]
SMRiP69783
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi4260572, 36 interactors
ComplexPortaliCPX-1978 Enzyme IIA-maltose transporter complex
DIPiDIP-31863N
IntActiP69783, 5 interactors
STRINGi511145.b2417

Protein family/group databases

TCDBi4.A.1.1.1 the pts glucose-glucoside (glc) family

PTM databases

iPTMnetiP69783

2D gel databases

SWISS-2DPAGEiP69783

Proteomic databases

EPDiP69783
jPOSTiP69783
PaxDbiP69783
PRIDEiP69783

Genome annotation databases

EnsemblBacteriaiAAC75470; AAC75470; b2417
BAA16291; BAA16291; BAA16291
GeneIDi946880
KEGGiecj:JW2410
eco:b2417
PATRICifig|1411691.4.peg.4314

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB0163
EcoGeneiEG10165 crr

Phylogenomic databases

eggNOGiENOG4105C5Y Bacteria
COG2190 LUCA
HOGENOMiHOG000224567
InParanoidiP69783
KOiK02777
PhylomeDBiP69783

Enzyme and pathway databases

BioCyciEcoCyc:CRR-MONOMER
ECOL316407:JW2410-MONOMER
MetaCyc:CRR-MONOMER

Miscellaneous databases

EvolutionaryTraceiP69783

Protein Ontology

More...
PROi
PR:P69783

Family and domain databases

Gene3Di2.70.70.10, 1 hit
InterProiView protein in InterPro
IPR011055 Dup_hybrid_motif
IPR001127 PTS_EIIA_1_perm
PfamiView protein in Pfam
PF00358 PTS_EIIA_1, 1 hit
SUPFAMiSSF51261 SSF51261, 1 hit
TIGRFAMsiTIGR00830 PTBA, 1 hit
PROSITEiView protein in PROSITE
PS51093 PTS_EIIA_TYPE_1, 1 hit
PS00371 PTS_EIIA_TYPE_1_HIS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPTGA_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P69783
Secondary accession number(s): P08837, Q47703
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: January 23, 2007
Last modified: September 18, 2019
This is version 129 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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