UniProtKB - P69781 (GAT12_ARATH)
Protein
GATA transcription factor 12
Gene
GATA12
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity). Transcription activator involved in xylem formation. Functions upstream of NAC030/VND7, a master switch of xylem vessel differentiation (PubMed:25265867).By similarity1 Publication
Miscellaneous
Overexpression of GATA12 induces the formation of ectopic xylem vessel-like elements.1 Publication
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 215 – 269 | GATA-typePROSITE-ProRule annotationAdd BLAST | 55 |
GO - Molecular functioni
- DNA-binding transcription factor activity Source: TAIR
- sequence-specific DNA binding Source: InterPro
- zinc ion binding Source: InterPro
GO - Biological processi
- cell differentiation Source: GO_Central
- cell wall organization Source: UniProtKB-KW
- circadian rhythm Source: TAIR
- multicellular organism development Source: UniProtKB-KW
- positive regulation of transcription, DNA-templated Source: InterPro
- response to light stimulus Source: TAIR
- tracheary element differentiation Source: UniProtKB
Keywordsi
Molecular function | Activator, Developmental protein, DNA-binding |
Biological process | Cell wall biogenesis/degradation, Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: GATA transcription factor 121 Publication |
Gene namesi | Name:GATA121 Publication Ordered Locus Names:At5g25830Imported ORF Names:F18A17.80Curated |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G25830 |
TAIRi | locus:2145259, AT5G25830 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000083442 | 1 – 331 | GATA transcription factor 12Add BLAST | 331 |
Proteomic databases
PaxDbi | P69781 |
PRIDEi | P69781 |
ProteomicsDBi | 230446 |
Expressioni
Tissue specificityi
Expressed in the vascular cylinder of roots. Expressed in the differentiation zone of the root stele.1 Publication
Gene expression databases
ExpressionAtlasi | P69781, baseline and differential |
Genevisiblei | P69781, AT |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 139 – 146 | Nuclear localization signalSequence analysis | 8 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 38 – 44 | Poly-Thr | 7 | |
Compositional biasi | 297 – 300 | Poly-His | 4 |
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 215 – 269 | GATA-typePROSITE-ProRule annotationAdd BLAST | 55 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | KOG1601, Eukaryota |
HOGENOMi | CLU_045755_0_0_1 |
InParanoidi | P69781 |
OMAi | RRQKEMH |
OrthoDBi | 1030219at2759 |
PhylomeDBi | P69781 |
Family and domain databases
CDDi | cd00202, ZnF_GATA, 1 hit |
Gene3Di | 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR016679, TF_GATA_pln IPR000679, Znf_GATA IPR013088, Znf_NHR/GATA |
Pfami | View protein in Pfam PF00320, GATA, 1 hit |
PIRSFi | PIRSF016992, TF_GATA_plant, 1 hit |
SMARTi | View protein in SMART SM00401, ZnF_GATA, 1 hit |
PROSITEi | View protein in PROSITE PS00344, GATA_ZN_FINGER_1, 1 hit PS50114, GATA_ZN_FINGER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P69781-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEDEAHEFFH TSDFAVDDLL VDFSNDDDEE NDVVADSTTT TTITDSSNFS
60 70 80 90 100
AADLPSFHGD VQDGTSFSGD LCIPSDDLAD ELEWLSNIVD ESLSPEDVHK
110 120 130 140 150
LELISGFKSR PDPKSDTGSP ENPNSSSPIF TTDVSVPAKA RSKRSRAAAC
160 170 180 190 200
NWASRGLLKE TFYDSPFTGE TILSSQQHLS PPTSPPLLMA PLGKKQAVDG
210 220 230 240 250
GHRRKKDVSS PESGGAEERR CLHCATDKTP QWRTGPMGPK TLCNACGVRY
260 270 280 290 300
KSGRLVPEYR PAASPTFVLA KHSNSHRKVM ELRRQKEMSR AHHEFIHHHH
310 320 330
GTDTAMIFDV SSDGDDYLIH HNVGPDFRQL I
Sequence cautioni
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005405 Genomic DNA No translation available. CP002688 Genomic DNA Translation: AED93492.1 AB493758 mRNA Translation: BAH30596.1 DQ875134 mRNA No translation available. |
RefSeqi | NP_197955.1, NM_122484.3 |
Genome annotation databases
EnsemblPlantsi | AT5G25830.1; AT5G25830.1; AT5G25830 |
GeneIDi | 832652 |
Gramenei | AT5G25830.1; AT5G25830.1; AT5G25830 |
KEGGi | ath:AT5G25830 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005405 Genomic DNA No translation available. CP002688 Genomic DNA Translation: AED93492.1 AB493758 mRNA Translation: BAH30596.1 DQ875134 mRNA No translation available. |
RefSeqi | NP_197955.1, NM_122484.3 |
3D structure databases
SMRi | P69781 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT5G25830.1 |
Proteomic databases
PaxDbi | P69781 |
PRIDEi | P69781 |
ProteomicsDBi | 230446 |
Genome annotation databases
EnsemblPlantsi | AT5G25830.1; AT5G25830.1; AT5G25830 |
GeneIDi | 832652 |
Gramenei | AT5G25830.1; AT5G25830.1; AT5G25830 |
KEGGi | ath:AT5G25830 |
Organism-specific databases
Araporti | AT5G25830 |
TAIRi | locus:2145259, AT5G25830 |
Phylogenomic databases
eggNOGi | KOG1601, Eukaryota |
HOGENOMi | CLU_045755_0_0_1 |
InParanoidi | P69781 |
OMAi | RRQKEMH |
OrthoDBi | 1030219at2759 |
PhylomeDBi | P69781 |
Miscellaneous databases
PROi | PR:P69781 |
Gene expression databases
ExpressionAtlasi | P69781, baseline and differential |
Genevisiblei | P69781, AT |
Family and domain databases
CDDi | cd00202, ZnF_GATA, 1 hit |
Gene3Di | 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR016679, TF_GATA_pln IPR000679, Znf_GATA IPR013088, Znf_NHR/GATA |
Pfami | View protein in Pfam PF00320, GATA, 1 hit |
PIRSFi | PIRSF016992, TF_GATA_plant, 1 hit |
SMARTi | View protein in SMART SM00401, ZnF_GATA, 1 hit |
PROSITEi | View protein in PROSITE PS00344, GATA_ZN_FINGER_1, 1 hit PS50114, GATA_ZN_FINGER_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GAT12_ARATH | |
Accessioni | P69781Primary (citable) accession number: P69781 Secondary accession number(s): C0SVQ5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | December 2, 2020 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families