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Protein

Conotoxin vc5c

Gene
N/A
Organism
Conus victoriae (Queen Victoria cone)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionToxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin vc5c1 Publication
Alternative name(s):
Vc5.21 Publication
OrganismiConus victoriae (Queen Victoria cone)
Taxonomic identifieri319920 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaNeogastropodaConoideaConidaeConusCylinder

Organism-specific databases

ConoServeri1522 VcVC precursor

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei‹1 – 14Sequence analysisAdd BLAST›14
PropeptideiPRO_000003504515 – 43By similarityAdd BLAST29
PeptideiPRO_000003504644 – 54Conotoxin vc5cAdd BLAST11

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi45 ↔ 52By similarity
Disulfide bondi46 ↔ 53By similarity
Modified residuei504-carboxyglutamate1 Publication1
Modified residuei516'-bromotryptophan1 Publication1

Keywords - PTMi

Bromination, Cleavage on pair of basic residues, Disulfide bond, Gamma-carboxyglutamic acid

Expressioni

Tissue specificityi

Expressed by the venom duct.

Structurei

3D structure databases

SMRiP69766
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The cysteine framework is V (CC-CC).

Sequence similaritiesi

Belongs to the conotoxin T superfamily.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR031565 T-conotoxin
PfamiView protein in Pfam
PF16981 Chi-conotoxin, 1 hit

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P69766-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
VILLLLIASI PSDAVQLKTK DDMPLASFHG NARRTLQMLS NKRICCYPNE

WCCD
Length:54
Mass (Da):6,107
Last modified:April 26, 2005 - v1
Checksum:i312189153AA57BD7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Similar proteinsi

Cross-referencesi

3D structure databases

SMRiP69766
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ConoServeri1522 VcVC precursor

Family and domain databases

InterProiView protein in InterPro
IPR031565 T-conotoxin
PfamiView protein in Pfam
PF16981 Chi-conotoxin, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCT5C_CONVC
AccessioniPrimary (citable) accession number: P69766
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: April 26, 2005
Last modified: September 12, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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