UniProtKB - P69437 (PROTO_AGEPP)
Protein
Protonectin
Gene
N/A
Organism
Agelaia pallipes pallipes (Neotropical social wasp)
Status
Functioni
Mast cell degranulator that induces a potent chemotaxis in polymorphonucleated leukocyte (PMNL) cells. Shows potent antimicrobial action against both Gram-positive and Gram-negative bacteria. Shows no hemolytic activity.2 Publications
Miscellaneous
In PubMed:15052574, it is unknown if amino acids 1 and 12 are Ile or Leu.
GO - Biological processi
- chemotaxis Source: UniProtKB-KW
- defense response to bacterium Source: UniProtKB-KW
Keywordsi
Molecular function | Antibiotic, Antimicrobial |
Biological process | Chemotaxis |
Names & Taxonomyi
Protein namesi | Recommended name: ProtonectinAlternative name(s): Agelaia-chemotactic peptide Short name: Agelaia-CP |
Organismi | Agelaia pallipes pallipes (Neotropical social wasp) |
Taxonomic identifieri | 313352 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Hymenoptera › Apocrita › Aculeata › Vespoidea › Vespidae › Polistinae › Epiponini › Agelaia |
Subcellular locationi
Extracellular region or secreted
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
PeptideiPRO_0000044212 | 1 – 12 | ProtonectinAdd BLAST | 12 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 12 | Leucine amide2 Publications | 1 |
Keywords - PTMi
AmidationExpressioni
Tissue specificityi
Expressed by the venom gland.
i Sequence
Sequence statusi: Complete.
Mass spectrometryi
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
MobiDBi | Search... |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Family and domain databases
ProtoNeti | Search... |
Entry informationi
Entry namei | PROTO_AGEPP | |
Accessioni | P69437Primary (citable) accession number: P69437 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 1, 2005 |
Last sequence update: | March 1, 2005 | |
Last modified: | August 30, 2017 | |
This is version 25 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- SIMILARITY comments
Index of protein domains and families