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Entry version 81 (26 Feb 2020)
Sequence version 2 (23 Jan 2007)
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Protein

Histone H2A, embryonic

Gene
N/A
Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histone H2A, embryonic
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStrongylocentrotus purpuratus (Purple sea urchin)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7668 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007110 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome core, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000552802 – 124Histone H2A, embryonicAdd BLAST123

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineBy similarity1
Modified residuei2PhosphoserineBy similarity1
Modified residuei104N5-methylglutamineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki119Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Monoubiquitination of Lys-119 gives a specific tag for epigenetic transcriptional repression.Curated
Phosphorylation of Ser-2 directly represses transcription.By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P69141

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P69141

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7668.SPU_027043-tr

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P69141

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the histone H2A family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1756 Eukaryota
COG5262 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_062828_3_3_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P69141

KEGG Orthology (KO)

More...
KOi
K11251

Identification of Orthologs from Complete Genome Data

More...
OMAi
TVGPKTP

Database of Orthologous Groups

More...
OrthoDBi
1504122at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00074 H2A, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.20.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009072 Histone-fold
IPR002119 Histone_H2A
IPR007125 Histone_H2A/H2B/H3
IPR032454 Histone_H2A_C
IPR032458 Histone_H2A_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00125 Histone, 1 hit
PF16211 Histone_H2A_C, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00620 HISTONEH2A

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00414 H2A, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47113 SSF47113, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00046 HISTONE_H2A, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P69141-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGRGKSGKA RTKAKTRSSR AGLQFPVGRV HRFLRKGNYA KRVGGGAPVY
60 70 80 90 100
MAAVLEYLTA EILELAGNAA RDNKKSRIIP RHLQLAVRND EELNKLLGGV
110 120
TIAQGGVLPN IQAVLLPKKT AKSS
Length:124
Mass (Da):13,332
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8282CADDF13005E6
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
V01357 Genomic DNA Translation: CAA24648.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A02598 HSUR7M

NCBI Reference Sequences

More...
RefSeqi
NP_001014426.1, NM_001014426.1
XP_001178526.1, XM_001178526.3
XP_011668420.1, XM_011670118.1
XP_011668423.1, XM_011670121.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
SPU_000466-tr; SPU_000466-tr; SPU_000466
SPU_000609-tr; SPU_000609-tr; SPU_000609
SPU_000833-tr; SPU_000833-tr; SPU_000833
SPU_000894-tr; SPU_000894-tr; SPU_000894
SPU_001635-tr; SPU_001635-tr; SPU_001635
SPU_002377-tr; SPU_002377-tr; SPU_002377
SPU_002577-tr; SPU_002577-tr; SPU_002577
SPU_002621-tr; SPU_002621-tr; SPU_002621
SPU_002805-tr; SPU_002805-tr; SPU_002805
SPU_005245-tr; SPU_005245-tr; SPU_005245
SPU_005934-tr; SPU_005934-tr; SPU_005934
SPU_007281-tr; SPU_007281-tr; SPU_007281
SPU_008232-tr; SPU_008232-tr; SPU_008232
SPU_008425-tr; SPU_008425-tr; SPU_008425
SPU_008451-tr; SPU_008451-tr; SPU_008451
SPU_008765-tr; SPU_008765-tr; SPU_008765
SPU_010863-tr; SPU_010863-tr; SPU_010863
SPU_011373-tr; SPU_011373-tr; SPU_011373
SPU_012737-tr; SPU_012737-tr; SPU_012737
SPU_014033-tr; SPU_014033-tr; SPU_014033
SPU_014506-tr; SPU_014506-tr; SPU_014506
SPU_014988-tr; SPU_014988-tr; SPU_014988
SPU_015686-tr; SPU_015686-tr; SPU_015686
SPU_016297-tr; SPU_016297-tr; SPU_016297
SPU_016809-tr; SPU_016809-tr; SPU_016809
SPU_016951-tr; SPU_016951-tr; SPU_016951
SPU_018161-tr; SPU_018161-tr; SPU_018161
SPU_018700-tr; SPU_018700-tr; SPU_018700
SPU_018896-tr; SPU_018896-tr; SPU_018896
SPU_019122-tr; SPU_019122-tr; SPU_019122
SPU_019321-tr; SPU_019321-tr; SPU_019321
SPU_019619-tr; SPU_019619-tr; SPU_019619
SPU_019867-tr; SPU_019867-tr; SPU_019867
SPU_020285-tr; SPU_020285-tr; SPU_020285
SPU_020438-tr; SPU_020438-tr; SPU_020438
SPU_020439-tr; SPU_020439-tr; SPU_020439
SPU_020521-tr; SPU_020521-tr; SPU_020521
SPU_021756-tr; SPU_021756-tr; SPU_021756
SPU_022660-tr; SPU_022660-tr; SPU_022660
SPU_023533-tr; SPU_023533-tr; SPU_023533
SPU_023891-tr; SPU_023891-tr; SPU_023891
SPU_023940-tr; SPU_023940-tr; SPU_023940
SPU_024477-tr; SPU_024477-tr; SPU_024477
SPU_025562-tr; SPU_025562-tr; SPU_025562
SPU_027043-tr; SPU_027043-tr; SPU_027043

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
373337
753951

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spu:373337
spu:753951

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V01357 Genomic DNA Translation: CAA24648.1
PIRiA02598 HSUR7M
RefSeqiNP_001014426.1, NM_001014426.1
XP_001178526.1, XM_001178526.3
XP_011668420.1, XM_011670118.1
XP_011668423.1, XM_011670121.1

3D structure databases

SMRiP69141
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7668.SPU_027043-tr

PTM databases

iPTMnetiP69141

Proteomic databases

PRIDEiP69141

Genome annotation databases

EnsemblMetazoaiSPU_000466-tr; SPU_000466-tr; SPU_000466
SPU_000609-tr; SPU_000609-tr; SPU_000609
SPU_000833-tr; SPU_000833-tr; SPU_000833
SPU_000894-tr; SPU_000894-tr; SPU_000894
SPU_001635-tr; SPU_001635-tr; SPU_001635
SPU_002377-tr; SPU_002377-tr; SPU_002377
SPU_002577-tr; SPU_002577-tr; SPU_002577
SPU_002621-tr; SPU_002621-tr; SPU_002621
SPU_002805-tr; SPU_002805-tr; SPU_002805
SPU_005245-tr; SPU_005245-tr; SPU_005245
SPU_005934-tr; SPU_005934-tr; SPU_005934
SPU_007281-tr; SPU_007281-tr; SPU_007281
SPU_008232-tr; SPU_008232-tr; SPU_008232
SPU_008425-tr; SPU_008425-tr; SPU_008425
SPU_008451-tr; SPU_008451-tr; SPU_008451
SPU_008765-tr; SPU_008765-tr; SPU_008765
SPU_010863-tr; SPU_010863-tr; SPU_010863
SPU_011373-tr; SPU_011373-tr; SPU_011373
SPU_012737-tr; SPU_012737-tr; SPU_012737
SPU_014033-tr; SPU_014033-tr; SPU_014033
SPU_014506-tr; SPU_014506-tr; SPU_014506
SPU_014988-tr; SPU_014988-tr; SPU_014988
SPU_015686-tr; SPU_015686-tr; SPU_015686
SPU_016297-tr; SPU_016297-tr; SPU_016297
SPU_016809-tr; SPU_016809-tr; SPU_016809
SPU_016951-tr; SPU_016951-tr; SPU_016951
SPU_018161-tr; SPU_018161-tr; SPU_018161
SPU_018700-tr; SPU_018700-tr; SPU_018700
SPU_018896-tr; SPU_018896-tr; SPU_018896
SPU_019122-tr; SPU_019122-tr; SPU_019122
SPU_019321-tr; SPU_019321-tr; SPU_019321
SPU_019619-tr; SPU_019619-tr; SPU_019619
SPU_019867-tr; SPU_019867-tr; SPU_019867
SPU_020285-tr; SPU_020285-tr; SPU_020285
SPU_020438-tr; SPU_020438-tr; SPU_020438
SPU_020439-tr; SPU_020439-tr; SPU_020439
SPU_020521-tr; SPU_020521-tr; SPU_020521
SPU_021756-tr; SPU_021756-tr; SPU_021756
SPU_022660-tr; SPU_022660-tr; SPU_022660
SPU_023533-tr; SPU_023533-tr; SPU_023533
SPU_023891-tr; SPU_023891-tr; SPU_023891
SPU_023940-tr; SPU_023940-tr; SPU_023940
SPU_024477-tr; SPU_024477-tr; SPU_024477
SPU_025562-tr; SPU_025562-tr; SPU_025562
SPU_027043-tr; SPU_027043-tr; SPU_027043
GeneIDi373337
753951
KEGGispu:373337
spu:753951

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
373337

Phylogenomic databases

eggNOGiKOG1756 Eukaryota
COG5262 LUCA
HOGENOMiCLU_062828_3_3_1
InParanoidiP69141
KOiK11251
OMAiTVGPKTP
OrthoDBi1504122at2759

Family and domain databases

CDDicd00074 H2A, 1 hit
Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR002119 Histone_H2A
IPR007125 Histone_H2A/H2B/H3
IPR032454 Histone_H2A_C
IPR032458 Histone_H2A_CS
PfamiView protein in Pfam
PF00125 Histone, 1 hit
PF16211 Histone_H2A_C, 1 hit
PRINTSiPR00620 HISTONEH2A
SMARTiView protein in SMART
SM00414 H2A, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
PROSITEiView protein in PROSITE
PS00046 HISTONE_H2A, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH2A_STRPU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P69141
Secondary accession number(s): P02271
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: February 26, 2020
This is version 81 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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