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Entry version 46 (08 May 2019)
Sequence version 1 (04 Jan 2005)
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Protein

Gametocyte surface protein P230

Gene

PF230

Organism
Plasmodium falciparum (isolate NF54)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Gametocyte surface protein required for male/female gamete fusion. Also required for male gamete exflagellation and interaction with erythrocytes.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Gametocyte surface protein P230
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PF230
Synonyms:S230
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate NF54)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5843 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Malaria

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002461621 – 3135Gametocyte surface protein P230Add BLAST3115

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi76N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi111N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi135N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi239N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi585N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi737 ↔ 781By similarity
Disulfide bondi804 ↔ 862By similarity
Glycosylationi821N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi829N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi889N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi961N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1079N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1089N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1140 ↔ 1161By similarity
Glycosylationi1153N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1175 ↔ 1251By similarity
Disulfide bondi1200 ↔ 1249By similarity
Glycosylationi1267N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1300N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1439 ↔ 1459By similarity
Glycosylationi1452N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1473 ↔ 1534By similarity
Disulfide bondi1483 ↔ 1532By similarity
Glycosylationi1492N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1508N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1621N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1624N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1753N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1804N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1882N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1914 ↔ 1938By similarity
Glycosylationi1920N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1952 ↔ 2017By similarity
Glycosylationi1954N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1963 ↔ 2015By similarity
Glycosylationi1972N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2178N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2199N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2208 ↔ 2229By similarity
Disulfide bondi2243 ↔ 2356By similarity
Disulfide bondi2254 ↔ 2354By similarity
Glycosylationi2312N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2351N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2439N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2452 ↔ 2476By similarity
Glycosylationi2457N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2466N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2504N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2586N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2611N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2650N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2670 ↔ 2706By similarity
Glycosylationi2677N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2688N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2720 ↔ 2804By similarity
Disulfide bondi2730 ↔ 2802By similarity
Glycosylationi2952N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2986 ↔ 3010By similarity
Glycosylationi3011N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3016N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi3024 ↔ 3090By similarity
Disulfide bondi3035 ↔ 3088By similarity
Glycosylationi3066N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3093N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3096N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P68875

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Specifically expressed in gametocytes.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterodimer; heterodimerizes with PF45/48.By similarity

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P68875

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini589 – 7306-Cys 1Add BLAST142
Domaini733 – 8876-Cys 2Add BLAST155
Domaini918 – 11336-Cys 3Add BLAST216
Domaini1136 – 12756-Cys 4Add BLAST140
Domaini1285 – 14326-Cys 5Add BLAST148
Domaini1435 – 15606-Cys 6Add BLAST126
Domaini1694 – 19076-Cys 7Add BLAST214
Domaini1910 – 20356-Cys 8Add BLAST126
Domaini2052 – 21996-Cys 9Add BLAST148
Domaini2204 – 23746-Cys 10Add BLAST171
Domaini2448 – 26636-Cys 11Add BLAST216
Domaini2666 – 28276-Cys 12Add BLAST162
Domaini2831 – 29796-Cys 13Add BLAST149
Domaini2982 – 31136-Cys 14Add BLAST132

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi280 – 476Glu-richAdd BLAST197
Compositional biasi1538 – 1541Poly-Lys4

Keywords - Domaini

Repeat, Signal

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.2860, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010884 6_CYS_dom
IPR038160 6_CYS_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07422 s48_45, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00970 s48_45, 9 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51701 6_CYS, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P68875-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKIITLKNL FLIILVYIFS EKKDLRCNVI KGNNIKDDED KRFHLFYYSH
60 70 80 90 100
NLFKTPETKE KKNKKECFYK NGGIYNLSKE IRMRKDTSVK IKQRTCPFHK
110 120 130 140 150
EGSSFEMGSK NITCFYPIVG KKERKTLDTI IIKKNVTNDH VVSSDMHSNV
160 170 180 190 200
QEKNMILIRN IDKENKNDIQ NVEEKIQRDT YENKDYESDD TLIEWFDDNT
210 220 230 240 250
NEENFLLTFL KRCLMKIFSS PKRKKTVVQK KHKSNFFINS SLKYIYMYLT
260 270 280 290 300
PSDSFNLVRR NRNLDEEDMS PRDNFVIDDE EEEEEEEEEE EEEEEEEEEE
310 320 330 340 350
EEEEYDDYVY EESGDETEEQ LQEEHQEEVG AESSEESFND EDEDSVEARD
360 370 380 390 400
GDMIRVDEYY EDQDGDTYDS TIKNEDVDEE VGEEVGEEVG EEVGEEVGEE
410 420 430 440 450
VGEEVGEEVG EEVGEEEGEE VGEGVGEEVG EEEGEEVGEE EGEYVDEKER
460 470 480 490 500
QGEIYPFGDE EEKDEGGESF TYEKSEVDKT DLFKFIEGGE GDDVYKVDGS
510 520 530 540 550
KVLLDDDTIS RVSKKHTARD GEYGEYGEAV EDGENVIKII RSVLQSGALP
560 570 580 590 600
SVGVDELDKI DLSYETTESG DTAVSEDSYD KYASNNTNKE YVCDFTDQLK
610 620 630 640 650
PTESGPKVKK CEVKVNEPLI KVKIICPLKG SVEKLYDNIE YVPKKSPYVV
660 670 680 690 700
LTKEETKLKE KLLSKLIYGL LISPTVNEKE NNFKEGVIEF TLPPVVHKAT
710 720 730 740 750
VFYFICDNSK TEDDNKKGNR GIVEVYVEPY GNKINGCAFL DEDEEEEKYG
760 770 780 790 800
NQIEEDEHNE KIKMKTFFTQ NIYKKNNIYP CYMKLYSGDI GGILFPKNIK
810 820 830 840 850
STTCFEEMIP YNKEIKWNKE NKSLGNLVNN SVVYNKEMNA KYFNVQYVHI
860 870 880 890 900
PTSYKDTLNL FCSIILKEEE SNLISTSYLV YVSINEELNF SLFDFYESFV
910 920 930 940 950
PIKKTIQVAQ KNVNNKEHDY TCDFTDKLDK TVPSTANGKK LFICRKHLKE
960 970 980 990 1000
FDTFTLKCNV NKTQYPNIEI FPKTLKDKKE VLKLDLDIQY QMFSKFFKFN
1010 1020 1030 1040 1050
TQNAKYLNLY PYYLIFPFNH IGKKELKNNP TYKNHKDVKY FEQSSVLSPL
1060 1070 1080 1090 1100
SSADSLGKLL NFLDTQETVC LTEKIRYLNL SINELGSDNN TFSVTFQVPP
1110 1120 1130 1140 1150
YIDIKEPFYF MFGCNNNKGE GNIGIVELLI SKQEEKIKGC NFHESKLDYF
1160 1170 1180 1190 1200
NENISSDTHE CTLHAYENDI IGFNCLETTH PNEVEVEVED AEIYLQPENC
1210 1220 1230 1240 1250
FNNVYKGLNS VDITTILKNA QTYNINNKKT PTFLKIPPYN LLEDVEISCQ
1260 1270 1280 1290 1300
CTIKQVVKKI KVIITKNDTV LLKREVQSES TLDDKIYKCE HENFINPRVN
1310 1320 1330 1340 1350
KTFDENVEYT CNIKIENFFN YIQIFCPAKD LGIYKNIQMY YDIVKPTRVP
1360 1370 1380 1390 1400
QFKKFNNEEL HKLIPNSEML HKTKEMLILY NEEKVDLLHF YVFLPIYIKD
1410 1420 1430 1440 1450
IYEFNIVCDN SKTMWKNQLG GKVIYHITVS KREQKVKGCS FDNEHAHMFS
1460 1470 1480 1490 1500
YNKTNVKNCI IDAKPKDLIG FVCPSGTLKL TNCFKDAIVH TNLTNINGIL
1510 1520 1530 1540 1550
YLKNNLANFT YKHQFNYMEI PALMDNDISF KCICVDLKKK KYNVKSPLGP
1560 1570 1580 1590 1600
KVLRALYKKL NIKFDNYVTG TDQNKYLMTY MDLHLSHKRN YLKELFHDLG
1610 1620 1630 1640 1650
KKKPADTDAN PESIIESLSI NESNESGPFP TGDVDAEHLI LEGYDTWESL
1660 1670 1680 1690 1700
YDEQLEEVIY NDIESLELKD IEQYVLQVNL KAPKLMMSAQ IHNNRHVCDF
1710 1720 1730 1740 1750
SKNNLIVPES LKKKEELGGN PVNIHCYALL KPLDTLYVKC PTSKDNYEAA
1760 1770 1780 1790 1800
KVNISENDNE YELQVISLIE KRFHNFETLE SKKPGNGDVV VHNGVVDTGP
1810 1820 1830 1840 1850
VLDNSTFEKY FKNIKIKPDK FFEKVINEYD DTEEEKDLES ILPGAIVSPM
1860 1870 1880 1890 1900
KVLKKKDPFT SYAAFVVPPI VPKDLHFKVE CNNTEYKDEN QYISGYNGII
1910 1920 1930 1940 1950
HIDISNSNRK INGCDFSTNN SSILTSSVKL VNGETKNCEI NINNNEVFGI
1960 1970 1980 1990 2000
ICDNETNLDP EKCFHEIYSK DNKTVKKFRE VIPNIDIFSL HNSNKKKVAY
2010 2020 2030 2040 2050
AKVPLDYINK LLFSCSCKTS HTNTIGTMKV TLNKDEKEEE DFKTAQGIKH
2060 2070 2080 2090 2100
NNVHLCNFFD NPELTFDNNK IVLCKIDAEL FSEVIIQLPI FGTKNVEEGV
2110 2120 2130 2140 2150
QNEEYKKFSL KPSLVFDDNN NDIKVIGKEK NEVSISLALK GVYGNRIFTF
2160 2170 2180 2190 2200
DKNGKKGEGI SFFIPPIKQD TDLKFIINET IDNSNIKQRG LIYIFVRKNV
2210 2220 2230 2240 2250
SENSFKLCDF TTGSTSLMEL NSQVKEKKCT VKIKKGDIFG LKCPKGFAIF
2260 2270 2280 2290 2300
PQACFSNVLL EYYKSDYEDS EHINYYIHKD KKYNLKPKDV IELMDENFRE
2310 2320 2330 2340 2350
LQNIQQYTGI SNITDVLHFK NFNLGNLPLN FKNHYSTAYA KVPDTFNSII
2360 2370 2380 2390 2400
NFSCNCYNPE KHVYGTMQVE SDNRNFDNIK KNENVIKNFL LPNIEKYALL
2410 2420 2430 2440 2450
LDDEERQKKI KQQQEEEQQE QILKDQDDRL SRHDDYNKNH TYILYDSNEH
2460 2470 2480 2490 2500
ICDYEKNESL ISTLPNDTKK IQKSICKINA KALDVVTIKC PHTKNFTPKD
2510 2520 2530 2540 2550
YFPNSSLITN DKKIVITFDK KNFVTYIDPT KKTFSLKDIY IQSFYGVSLD
2560 2570 2580 2590 2600
HLNQIKKIHE EWDDVHLFYP PHNVLHNVVL NNHIVNLSSA LEGVLFMKSK
2610 2620 2630 2640 2650
VTGDETATKK NTTLPTDGVS SILIPPYVKE DITFHLFCGK STTKKPNKKN
2660 2670 2680 2690 2700
TSLALIHIHI SSNRNIIHGC DFLYLENQTN DAISNNNNNS YSIFTHNKNT
2710 2720 2730 2740 2750
ENNLICDISL IPKTVIGIKC PNKKLNPQTC FDEVYYVKQE DVPSKTITAD
2760 2770 2780 2790 2800
KYNTFSKDKI GNILKNAISI NNPDEKDNTY TYLILPEKFE EELIDTKKVL
2810 2820 2830 2840 2850
ACTCDNKYII HMKIEKSTMD KIKIDEKKTI GKDICKYDVT TKVATCEIID
2860 2870 2880 2890 2900
TIDSSVLKEH HTVHYSITLS RWDKLIIKYP TNEKTHFENF FVNPFNLKDK
2910 2920 2930 2940 2950
VLYNYNKPIN IEHILPGAIT TDIYDTRTKI KQYILRIPPY VHKDIHFSLE
2960 2970 2980 2990 3000
FNNSLSLTKQ NQNIIYGNVA KIFIHINQGY KEIHGCDFTG KYSHLFTYSK
3010 3020 3030 3040 3050
KPLPNDDDIC NVTIGNNTFS GFACLSHFEL KPNNCFSSVY DYNEANKVKK
3060 3070 3080 3090 3100
LFDLSTKVEL DHIKQNTSGY TLSYIIFNKE STKLKFSCTC SSNYSNYTIR
3110 3120 3130
ITFDPNYIIP EPQSRAIIKY VDLQDKNFAK YLRKL
Length:3,135
Mass (Da):363,218
Last modified:January 4, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBE5F850C87ED9C77
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
L08135 mRNA Translation: AAA29734.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A48584

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L08135 mRNA Translation: AAA29734.1
PIRiA48584

3D structure databases

SMRiP68875
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP68875

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.2860, 6 hits
InterProiView protein in InterPro
IPR010884 6_CYS_dom
IPR038160 6_CYS_dom_sf
PfamiView protein in Pfam
PF07422 s48_45, 8 hits
SMARTiView protein in SMART
SM00970 s48_45, 9 hits
PROSITEiView protein in PROSITE
PS51701 6_CYS, 14 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiP230_PLAFO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P68875
Secondary accession number(s): Q08372
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: January 4, 2005
Last modified: May 8, 2019
This is version 46 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing
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