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Protein

Outer membrane protein YopN

Gene

yopN

Organism
Yersinia pestis
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a major role in regulation of the low-calcium response. Seems to sense the calcium concentration and to transmit a signal to shut off yop transcription when the calcium concentration is high (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processVirulence
LigandCalcium

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protein YopN
Alternative name(s):
LcrE
Yop4b
Gene namesi
Name:yopN
Synonyms:lcrE
Ordered Locus Names:YPCD1.39c, y5039, y0042, YP_pCD44
Encoded oniPlasmid pCD10 Publication
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Plasmid pCD1
  • UP000001019 Componenti: Plasmid pCD1

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000663712 – 293Outer membrane protein YopNAdd BLAST292

Proteomic databases

PRIDEiP68640

Structurei

Secondary structure

1293
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi39 – 42Combined sources4
Helixi49 – 56Combined sources8
Beta strandi73 – 75Combined sources3
Helixi76 – 91Combined sources16
Helixi102 – 110Combined sources9
Helixi118 – 121Combined sources4
Helixi124 – 127Combined sources4
Helixi132 – 136Combined sources5
Helixi139 – 146Combined sources8
Helixi150 – 152Combined sources3
Helixi153 – 188Combined sources36
Beta strandi191 – 193Combined sources3
Helixi195 – 207Combined sources13
Helixi212 – 220Combined sources9
Helixi228 – 236Combined sources9
Helixi239 – 245Combined sources7
Helixi250 – 253Combined sources4
Helixi256 – 263Combined sources8
Helixi272 – 275Combined sources4
Helixi278 – 282Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XKPX-ray1.70A33-277[»]
1XL3X-ray2.20A/B76-293[»]
ProteinModelPortaliP68640
SMRiP68640
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP68640

Family & Domainsi

Sequence similaritiesi

Belongs to the HrpJ/YopN family.Curated

Phylogenomic databases

HOGENOMiHOG000219605
KOiK04058
OMAiGINAIWS

Family and domain databases

InterProiView protein in InterPro
IPR010812 HrpJ-like
IPR013401 T3SS_LcrE
PfamiView protein in Pfam
PF07201 HrpJ, 1 hit
TIGRFAMsiTIGR02568 LcrE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P68640-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTLHNLSYG NTPLHNERPE IASSQIVNQT LGQFRGESVQ IVSGTLQSIA
60 70 80 90 100
DMAEEVTFVF SERKELSLDK RKLSDSQARV SDVEEQVNQY LSKVPELEQK
110 120 130 140 150
QNVSELLSLL SNSPNISLSQ LKAYLEGKSE EPSEQFKMLC GLRDALKGRP
160 170 180 190 200
ELAHLSHLVE QALVSMAEEQ GETIVLGARI TPEAYRESQS GVNPLQPLRD
210 220 230 240 250
TYRDAVMGYQ GIYAIWSDLQ KRFPNGDIDS VILFLQKALS ADLQSQQSGS
260 270 280 290
GREKLGIVIS DLQKLKEFGS VSDQVKGFWQ FFSEGKTNGV RPF
Length:293
Mass (Da):32,670
Last modified:January 23, 2007 - v2
Checksum:i89AF200F36B4382C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti66L → F in AAS58563 (PubMed:15368893).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF074612 Genomic DNA Translation: AAC69792.1
AF053946 Genomic DNA Translation: AAC62565.1
AL117189 Genomic DNA Translation: CAB54916.1
AE017043 Genomic DNA Translation: AAS58563.1
PIRiT43586
RefSeqiNP_395173.1, NC_003131.1
NP_857743.1, NC_004836.1
NP_857938.1, NC_004839.1
WP_002212958.1, NZ_LT605014.1

Genome annotation databases

EnsemblBacteriaiAAS58563; AAS58563; YP_pCD44
GeneIDi1149302
1172684
15151838
KEGGiype:YPCD1.39c
ypm:YP_pCD44
PATRICifig|214092.21.peg.50

Similar proteinsi

Entry informationi

Entry nameiYOPN_YERPE
AccessioniPrimary (citable) accession number: P68640
Secondary accession number(s): P16160
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 95 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Plasmid, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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