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UniProtKB - P68158 (EFTU_TOBAC)
Protein
Elongation factor Tu, chloroplastic
Gene
TUFA
Organism
Nicotiana tabacum (Common tobacco)
Status
Functioni
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 88 – 95 | GTPBy similarity | 8 | |
Nucleotide bindingi | 150 – 154 | GTPBy similarity | 5 | |
Nucleotide bindingi | 205 – 208 | GTPBy similarity | 4 |
GO - Molecular functioni
- GTPase activity Source: InterPro
- GTP binding Source: UniProtKB-KW
- translation elongation factor activity Source: GO_Central
GO - Biological processi
- mitochondrial translational elongation Source: GO_Central
- translational elongation Source: GO_Central
Keywordsi
Molecular function | Elongation factor |
Biological process | Protein biosynthesis |
Ligand | GTP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Elongation factor Tu, chloroplasticShort name: EF-Tu |
Gene namesi | Name:TUFA |
Organismi | Nicotiana tabacum (Common tobacco) |
Taxonomic identifieri | 4097 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › asterids › lamiids › Solanales › Solanaceae › Nicotianoideae › Nicotianeae › Nicotiana |
Proteomesi |
|
Subcellular locationi
Chloroplast
Chloroplast
- chloroplast Source: UniProtKB-SubCell
Mitochondrion
- mitochondrion Source: GO_Central
Keywords - Cellular componenti
Chloroplast, PlastidPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 69 | ChloroplastSequence analysisAdd BLAST | 69 | |
ChainiPRO_0000007460 | 70 – 478 | Elongation factor Tu, chloroplasticAdd BLAST | 409 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 79 – 283 | tr-type GAdd BLAST | 205 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 31 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 88 – 95 | G1By similarity | 8 | |
Regioni | 129 – 133 | G2By similarity | 5 | |
Regioni | 150 – 153 | G3By similarity | 4 | |
Regioni | 205 – 208 | G4By similarity | 4 | |
Regioni | 243 – 245 | G5By similarity | 3 |
Sequence similaritiesi
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
OMAi | PFLCAIE |
OrthoDBi | 491836at2759 |
Family and domain databases
CDDi | cd01884, EF_Tu, 1 hit cd03697, EFTU_II, 1 hit |
Gene3Di | 3.40.50.300, 1 hit |
HAMAPi | MF_00118_B, EF_Tu_B, 1 hit |
InterProi | View protein in InterPro IPR041709, EF-Tu_GTP-bd IPR004161, EFTu-like_2 IPR033720, EFTU_2 IPR031157, G_TR_CS IPR027417, P-loop_NTPase IPR005225, Small_GTP-bd_dom IPR000795, T_Tr_GTP-bd_dom IPR009000, Transl_B-barrel_sf IPR009001, Transl_elong_EF1A/Init_IF2_C IPR004541, Transl_elong_EFTu/EF1A_bac/org IPR004160, Transl_elong_EFTu/EF1A_C |
Pfami | View protein in Pfam PF00009, GTP_EFTU, 1 hit PF03144, GTP_EFTU_D2, 1 hit PF03143, GTP_EFTU_D3, 1 hit |
PRINTSi | PR00315, ELONGATNFCT |
SUPFAMi | SSF50447, SSF50447, 1 hit SSF50465, SSF50465, 1 hit SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00485, EF-Tu, 1 hit TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS00301, G_TR_1, 1 hit PS51722, G_TR_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P68158-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASISAATAT SSTKLVSSNS TNPLLPSSTK PSKLILSSSF TPNCSTLFLH
60 70 80 90 100
SPATPSSTAT HRHRRFTVRA ARGKFERKKP HVNIGTIGHV DHGKTTLTAA
110 120 130 140 150
LTMALASMGN SAPKKYDEID AAPEERARGI TINTATVEYE TENRHYAHVD
160 170 180 190 200
CPGHADYVKN MITGAAQMDG AILVCSGADG PMPQTKEHIL LAKQVGVPNM
210 220 230 240 250
VVFLNKQDQV DDEELLQLVE LEVRELLSSY EFPGDDIPII SGSALLALEA
260 270 280 290 300
LMANPSIKRG ENQWVDKIYE LMDAVDSYIP IPVRQTELPF LMAIEDVFSI
310 320 330 340 350
TGRGTVATGR VERGTVRIGD TVDIVGLKDT RSTTVTGVEM FQKILDEAMA
360 370 380 390 400
GDNVGLLLRG IQKIDIQRGM VLAKPGTITP HTKFEAIVYV LKKEEGGRHS
410 420 430 440 450
PFFSGYRPQF YMRTTDVTGK VTSITTDKGE ESKMVMPGDR VNLVVELIMP
460 470
VACEQGMRFA IREGGKTVGA GVIQKIIE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M94204 Unassigned DNA Translation: AAA18546.1 |
PIRi | JQ2240 S39153 |
RefSeqi | XP_016478946.1, XM_016623460.1 |
Genome annotation databases
GeneIDi | 107800308 |
KEGGi | nta:107800308 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M94204 Unassigned DNA Translation: AAA18546.1 |
PIRi | JQ2240 S39153 |
RefSeqi | XP_016478946.1, XM_016623460.1 |
3D structure databases
SMRi | P68158 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4097.P68158 |
Genome annotation databases
GeneIDi | 107800308 |
KEGGi | nta:107800308 |
Phylogenomic databases
OMAi | PFLCAIE |
OrthoDBi | 491836at2759 |
Family and domain databases
CDDi | cd01884, EF_Tu, 1 hit cd03697, EFTU_II, 1 hit |
Gene3Di | 3.40.50.300, 1 hit |
HAMAPi | MF_00118_B, EF_Tu_B, 1 hit |
InterProi | View protein in InterPro IPR041709, EF-Tu_GTP-bd IPR004161, EFTu-like_2 IPR033720, EFTU_2 IPR031157, G_TR_CS IPR027417, P-loop_NTPase IPR005225, Small_GTP-bd_dom IPR000795, T_Tr_GTP-bd_dom IPR009000, Transl_B-barrel_sf IPR009001, Transl_elong_EF1A/Init_IF2_C IPR004541, Transl_elong_EFTu/EF1A_bac/org IPR004160, Transl_elong_EFTu/EF1A_C |
Pfami | View protein in Pfam PF00009, GTP_EFTU, 1 hit PF03144, GTP_EFTU_D2, 1 hit PF03143, GTP_EFTU_D3, 1 hit |
PRINTSi | PR00315, ELONGATNFCT |
SUPFAMi | SSF50447, SSF50447, 1 hit SSF50465, SSF50465, 1 hit SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00485, EF-Tu, 1 hit TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS00301, G_TR_1, 1 hit PS51722, G_TR_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | EFTU_TOBAC | |
Accessioni | P68158Primary (citable) accession number: P68158 Secondary accession number(s): P41342 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 25, 2004 |
Last sequence update: | October 25, 2004 | |
Last modified: | February 23, 2022 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families