UniProtKB - P68082 (MYG_HORSE)
Protein
Myoglobin
Gene
MB
Organism
Equus caballus (Horse)
Status
Functioni
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 65 | Iron (heme distal ligand)1 Publication | 1 | |
Metal bindingi | 94 | Iron (heme proximal ligand)Combined sources3 Publications | 1 |
GO - Molecular functioni
- heme binding Source: InterPro
- metal ion binding Source: UniProtKB-KW
- oxygen binding Source: GO_Central
- oxygen carrier activity Source: UniProtKB-KW
GO - Biological processi
- oxygen transport Source: GO_Central
Keywordsi
Molecular function | Muscle protein |
Biological process | Oxygen transport, Transport |
Ligand | Heme, Iron, Metal-binding |
Enzyme and pathway databases
SABIO-RKi | P68082 |
Names & Taxonomyi
Protein namesi | Recommended name: Myoglobin |
Gene namesi | Name:MB |
Organismi | Equus caballus (Horse) |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:20004, MB |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed3 Publications | |||
ChainiPRO_0000053302 | 2 – 154 | MyoglobinAdd BLAST | 153 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 4 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
CPTACi | CPTAC-1474 |
PaxDbi | P68082 |
PRIDEi | P68082 |
PTM databases
CarbonylDBi | P68082 |
Expressioni
Gene expression databases
Bgeei | ENSECAG00000017982, Expressed in gluteus medius and 12 other tissues |
ExpressionAtlasi | P68082, baseline |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
BMRBi | P68082 |
PCDDBi | P68082 |
SASBDBi | P68082 |
SMRi | P68082 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P68082 |
Family & Domainsi
Sequence similaritiesi
Belongs to the globin family.PROSITE-ProRule annotation
Phylogenomic databases
GeneTreei | ENSGT00940000160809 |
HOGENOMi | CLU_003827_18_0_1 |
InParanoidi | P68082 |
OMAi | AQGAMRK |
OrthoDBi | 1405713at2759 |
TreeFami | TF332967 |
Family and domain databases
Gene3Di | 1.10.490.10, 1 hit |
InterProi | View protein in InterPro IPR000971, Globin IPR009050, Globin-like_sf IPR012292, Globin/Proto IPR002335, Myoglobin |
PANTHERi | PTHR47132, PTHR47132, 1 hit |
Pfami | View protein in Pfam PF00042, Globin, 1 hit |
PRINTSi | PR00613, MYOGLOBIN |
SUPFAMi | SSF46458, SSF46458, 1 hit |
PROSITEi | View protein in PROSITE PS01033, GLOBIN, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
P68082-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGLSDGEWQQ VLNVWGKVEA DIAGHGQEVL IRLFTGHPET LEKFDKFKHL
60 70 80 90 100
KTEAEMKASE DLKKHGTVVL TALGGILKKK GHHEAELKPL AQSHATKHKI
110 120 130 140 150
PIKYLEFISD AIIHVLHSKH PGDFGADAQG AMTKALELFR NDIAAKYKEL
GFQG
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A452GEN9 | A0A452GEN9_HORSE | Myoglobin | MB | 162 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 123 | D → N AA sequence (PubMed:4902609).Curated | 1 |
Sequence databases
PIRi | A91098, MYHO |
RefSeqi | NP_001157488.1, NM_001164016.1 |
Genome annotation databases
Ensembli | ENSECAT00000036478; ENSECAP00000026577; ENSECAG00000017982 |
GeneIDi | 100054434 |
KEGGi | ecb:100054434 |
Similar proteinsi
Cross-referencesi
Sequence databases
PIRi | A91098, MYHO |
RefSeqi | NP_001157488.1, NM_001164016.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1AZI | X-ray | 2.00 | A | 2-154 | [»] | |
1BJE | X-ray | 1.80 | A | 2-154 | [»] | |
1DWR | X-ray | 1.45 | A | 2-154 | [»] | |
1DWS | X-ray | 1.45 | A | 2-154 | [»] | |
1DWT | X-ray | 1.40 | A | 2-154 | [»] | |
1GJN | X-ray | 1.35 | A | 2-154 | [»] | |
1HRM | X-ray | 1.70 | A | 2-154 | [»] | |
1HSY | X-ray | 1.90 | A | 2-154 | [»] | |
1NPF | X-ray | 1.90 | A | 2-154 | [»] | |
1NPG | X-ray | 1.70 | A | 2-154 | [»] | |
1NZ2 | X-ray | 1.90 | A | 2-154 | [»] | |
1NZ3 | X-ray | 1.60 | A | 2-154 | [»] | |
1NZ4 | X-ray | 1.80 | A | 2-154 | [»] | |
1NZ5 | X-ray | 1.70 | A | 2-154 | [»] | |
1RSE | X-ray | 1.70 | A | 2-154 | [»] | |
1WLA | X-ray | 1.70 | A | 2-154 | [»] | |
1XCH | X-ray | 1.70 | A | 2-154 | [»] | |
1YMA | X-ray | 2.00 | A | 2-154 | [»] | |
1YMB | X-ray | 1.90 | A | 2-154 | [»] | |
1YMC | X-ray | 2.00 | A | 2-154 | [»] | |
2FRF | X-ray | 1.20 | A | 2-154 | [»] | |
2FRI | X-ray | 1.60 | X | 2-154 | [»] | |
2FRJ | X-ray | 1.30 | X | 2-154 | [»] | |
2FRK | X-ray | 1.30 | X | 2-154 | [»] | |
2IN4 | X-ray | 2.15 | A | 2-154 | [»] | |
2NSR | X-ray | 1.90 | A | 2-154 | [»] | |
2NSS | X-ray | 2.00 | A | 2-154 | [»] | |
2O58 | X-ray | 1.65 | X | 2-154 | [»] | |
2O5B | X-ray | 2.00 | X | 2-154 | [»] | |
2O5L | X-ray | 1.70 | X | 2-154 | [»] | |
2O5M | X-ray | 1.65 | X | 2-154 | [»] | |
2O5O | X-ray | 1.60 | X | 2-154 | [»] | |
2O5Q | X-ray | 1.90 | X | 2-154 | [»] | |
2O5S | X-ray | 1.60 | X | 2-154 | [»] | |
2O5T | X-ray | 1.60 | X | 2-154 | [»] | |
2V1E | X-ray | 1.30 | A | 2-154 | [»] | |
2V1F | X-ray | 1.20 | A | 2-154 | [»] | |
2V1G | X-ray | 1.35 | A | 2-154 | [»] | |
2V1H | X-ray | 1.30 | A | 2-154 | [»] | |
2V1I | X-ray | 1.20 | A | 2-154 | [»] | |
2V1J | X-ray | 1.40 | A | 2-154 | [»] | |
2V1K | X-ray | 1.25 | A | 2-154 | [»] | |
2VLX | X-ray | 1.30 | A | 2-154 | [»] | |
2VLY | X-ray | 1.60 | A | 2-154 | [»] | |
2VLZ | X-ray | 1.50 | A | 2-154 | [»] | |
2VM0 | X-ray | 1.60 | A | 2-154 | [»] | |
3BA2 | X-ray | 1.80 | A | 2-154 | [»] | |
3HC9 | X-ray | 2.00 | A | 2-154 | [»] | |
3HEN | X-ray | 1.90 | A | 2-154 | [»] | |
3HEO | X-ray | 2.00 | A | 2-154 | [»] | |
3HEP | X-ray | 1.95 | A | 2-154 | [»] | |
3LR7 | X-ray | 1.60 | A | 2-154 | [»] | |
3LR9 | X-ray | 1.55 | A | 2-154 | [»] | |
3RJ6 | X-ray | 1.23 | A/B | 2-154 | [»] | |
3RJN | X-ray | 1.90 | B | 2-154 | [»] | |
3V2V | X-ray | 1.65 | A | 2-154 | [»] | |
3V2Z | X-ray | 1.65 | A | 2-154 | [»] | |
3VAU | X-ray | 1.70 | A | 2-154 | [»] | |
3VM9 | X-ray | 1.05 | A/B | 2-154 | [»] | |
3WFT | X-ray | 1.30 | A | 2-154 | [»] | |
3WFU | X-ray | 1.35 | A | 2-154 | [»] | |
3WI8 | X-ray | 2.20 | A | 2-154 | [»] | |
3WYO | X-ray | 2.00 | A/B/C/D | 2-154 | [»] | |
4DC7 | X-ray | 1.50 | A | 2-153 | [»] | |
4DC8 | X-ray | 1.50 | A | 2-153 | [»] | |
4NS2 | X-ray | 1.18 | A | 1-154 | [»] | |
4TWU | X-ray | 1.08 | A | 1-154 | [»] | |
4TWV | X-ray | 1.06 | A | 1-154 | [»] | |
5AZQ | X-ray | 1.40 | A | 2-154 | [»] | |
5AZR | X-ray | 1.20 | A | 2-154 | [»] | |
5CMV | X-ray | 1.80 | A | 2-153 | [»] | |
5CN4 | X-ray | 1.80 | A | 2-153 | [»] | |
5CN5 | X-ray | 1.80 | A | 2-153 | [»] | |
5CN6 | X-ray | 1.80 | A | 2-153 | [»] | |
5CN7 | X-ray | 1.80 | A | 2-153 | [»] | |
5CN8 | X-ray | 1.80 | A | 2-153 | [»] | |
5CN9 | X-ray | 1.80 | A | 2-153 | [»] | |
5CNB | X-ray | 1.80 | A | 2-153 | [»] | |
5CNC | X-ray | 1.80 | A | 2-153 | [»] | |
5CND | X-ray | 1.80 | A | 2-153 | [»] | |
5CNE | X-ray | 1.80 | A | 2-153 | [»] | |
5CNF | X-ray | 1.80 | A | 2-153 | [»] | |
5CNG | X-ray | 1.80 | A | 2-153 | [»] | |
5D5R | X-ray | 1.60 | A | 2-153 | [»] | |
5YCG | X-ray | 2.40 | A | 1-154 | [»] | |
5YL3 | X-ray | 1.50 | A | 1-154 | [»] | |
5Z7E | X-ray | 1.80 | A | 2-154 | [»] | |
5Z7F | X-ray | 1.90 | A | 2-154 | [»] | |
5ZZE | X-ray | 1.42 | A | 2-153 | [»] | |
6LS8 | X-ray | 2.30 | A/C/E/G/I/K | 2-154 | [»] | |
6LTL | X-ray | 1.25 | A/B | 2-154 | [»] | |
6LTM | X-ray | 1.65 | A/B | 2-154 | [»] | |
BMRBi | P68082 | |||||
PCDDBi | P68082 | |||||
SASBDBi | P68082 | |||||
SMRi | P68082 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein family/group databases
Allergomei | 10877, Equ c Myoglobin |
PTM databases
CarbonylDBi | P68082 |
Proteomic databases
CPTACi | CPTAC-1474 |
PaxDbi | P68082 |
PRIDEi | P68082 |
Protocols and materials databases
ABCDi | P68082, 1 sequenced antibody |
Genome annotation databases
Ensembli | ENSECAT00000036478; ENSECAP00000026577; ENSECAG00000017982 |
GeneIDi | 100054434 |
KEGGi | ecb:100054434 |
Organism-specific databases
CTDi | 4151 |
VGNCi | VGNC:20004, MB |
Phylogenomic databases
GeneTreei | ENSGT00940000160809 |
HOGENOMi | CLU_003827_18_0_1 |
InParanoidi | P68082 |
OMAi | AQGAMRK |
OrthoDBi | 1405713at2759 |
TreeFami | TF332967 |
Enzyme and pathway databases
SABIO-RKi | P68082 |
Miscellaneous databases
EvolutionaryTracei | P68082 |
Gene expression databases
Bgeei | ENSECAG00000017982, Expressed in gluteus medius and 12 other tissues |
ExpressionAtlasi | P68082, baseline |
Family and domain databases
Gene3Di | 1.10.490.10, 1 hit |
InterProi | View protein in InterPro IPR000971, Globin IPR009050, Globin-like_sf IPR012292, Globin/Proto IPR002335, Myoglobin |
PANTHERi | PTHR47132, PTHR47132, 1 hit |
Pfami | View protein in Pfam PF00042, Globin, 1 hit |
PRINTSi | PR00613, MYOGLOBIN |
SUPFAMi | SSF46458, SSF46458, 1 hit |
PROSITEi | View protein in PROSITE PS01033, GLOBIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MYG_HORSE | |
Accessioni | P68082Primary (citable) accession number: P68082 Secondary accession number(s): P02188 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 119 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families