UniProtKB - P68069 (HBG_ATEPA)
Protein
Hemoglobin subunit gamma
Gene
HBG
Organism
Ateles paniscus (Black spider monkey) (Red-faced black spider monkey)
Status
Functioni
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 64 | Iron (heme distal ligand)PROSITE-ProRule annotation | 1 | |
Metal bindingi | 93 | Iron (heme proximal ligand)PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- heme binding Source: InterPro
- metal ion binding Source: UniProtKB-KW
- oxygen binding Source: InterPro
- oxygen carrier activity Source: UniProtKB-KW
Keywordsi
Biological process | Oxygen transport, Transport |
Ligand | Heme, Iron, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Hemoglobin subunit gammaAlternative name(s): Gamma-globin Hemoglobin gamma chain |
Gene namesi | Name:HBG |
Organismi | Ateles paniscus (Black spider monkey) (Red-faced black spider monkey) |
Taxonomic identifieri | 9510 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Platyrrhini › Atelidae › Atelinae › Ateles |
Subcellular locationi
Cytosol
- hemoglobin complex Source: InterPro
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000053238 | 1 – 147 | Hemoglobin subunit gammaAdd BLAST | 147 |
Proteomic databases
PRIDEi | P68069 |
Expressioni
Tissue specificityi
Red blood cells.
Interactioni
Subunit structurei
Heterotetramer of two alpha chains and two gamma chains in fetal hemoglobin (Hb F).
Family & Domainsi
Sequence similaritiesi
Belongs to the globin family.PROSITE-ProRule annotation
Family and domain databases
CDDi | cd08925 Hb-beta_like, 1 hit |
Gene3Di | 1.10.490.10, 1 hit |
InterProi | View protein in InterPro IPR000971 Globin IPR009050 Globin-like_sf IPR012292 Globin/Proto IPR002337 Haemoglobin_b |
Pfami | View protein in Pfam PF00042 Globin, 1 hit |
PRINTSi | PR00814 BETAHAEM |
SUPFAMi | SSF46458 SSF46458, 1 hit |
PROSITEi | View protein in PROSITE PS01033 GLOBIN, 1 hit |
i Sequence
Sequence statusi: Complete.
P68069-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSNFTAEDKA AITSLWGKVN VEDAGGETLG RLLVVYPWTQ RFFDSFGSLS
60 70 80 90 100
SPSAIMGNPK VKAHGVKVLT SLGEAIKNLD DLKGTFGQLS ELHCDKLHVD
110 120 130 140
PENFRLLGNV LVTVLAILHG KEFTPEVQAS WQKMVAGVAS ALASRYH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF030093 Genomic DNA Translation: AAB92227.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF030093 Genomic DNA Translation: AAB92227.1 |
3D structure databases
SMRi | P68069 |
ModBasei | Search... |
Proteomic databases
PRIDEi | P68069 |
Family and domain databases
CDDi | cd08925 Hb-beta_like, 1 hit |
Gene3Di | 1.10.490.10, 1 hit |
InterProi | View protein in InterPro IPR000971 Globin IPR009050 Globin-like_sf IPR012292 Globin/Proto IPR002337 Haemoglobin_b |
Pfami | View protein in Pfam PF00042 Globin, 1 hit |
PRINTSi | PR00814 BETAHAEM |
SUPFAMi | SSF46458 SSF46458, 1 hit |
PROSITEi | View protein in PROSITE PS01033 GLOBIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | HBG_ATEPA | |
Accessioni | P68069Primary (citable) accession number: P68069 Secondary accession number(s): P06891 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1988 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 8, 2019 | |
This is version 59 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |