UniProtKB - P67729 (YFEO_ECOLI)
Protein
Putative ion-transport protein YfeO
Gene
yfeO
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- voltage-gated chloride channel activity Source: InterPro
Keywordsi
Molecular function | Ion channel |
Biological process | Ion transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:G7251-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Putative ion-transport protein YfeO |
Gene namesi | Name:yfeO Ordered Locus Names:b2389, JW2386 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell membrane Curated; Multi-pass membrane protein Curated
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 9 – 31 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 55 – 77 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 90 – 112 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 122 – 140 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 147 – 169 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 189 – 211 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 223 – 244 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 259 – 281 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 301 – 323 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 343 – 363 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 376 – 398 | HelicalSequence analysisAdd BLAST | 23 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000094494 | 1 – 418 | Putative ion-transport protein YfeOAdd BLAST | 418 |
Proteomic databases
PaxDbi | P67729 |
PRIDEi | P67729 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259181, 309 interactors |
STRINGi | 511145.b2389 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0038, Bacteria |
HOGENOMi | CLU_053130_0_0_6 |
InParanoidi | P67729 |
Family and domain databases
Gene3Di | 1.10.3080.10, 1 hit |
HAMAPi | MF_01115, CLC_YfeO, 1 hit |
InterProi | View protein in InterPro IPR022969, Chloride_channel_YfeO IPR014743, Cl-channel_core IPR001807, Cl-channel_volt-gated |
Pfami | View protein in Pfam PF00654, Voltage_CLC, 1 hit |
PRINTSi | PR00762, CLCHANNEL |
SUPFAMi | SSF81340, SSF81340, 1 hit |
i Sequence
Sequence statusi: Complete.
P67729-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLHPRARTML LLSLPAVAIG IASSLILIVV MKIASVLQNL LWQRLPGTLG
60 70 80 90 100
IAQDSPLWII GVLTLTGIAV GLVIRFSQGH AGPDPACEPL IGAPVPPSAL
110 120 130 140 150
PGLIVALILG LAGGVSLGPE HPIMTVNIAL AVAIGARLLP RVNRMEWTIL
160 170 180 190 200
ASAGTIGALF GTPVAAALIF SQTLNGSSEV PLWDRLFAPL MAAAAGALTT
210 220 230 240 250
GLFFHPHFSL PIAHYGQMEM TDILSGAIVA AIAIAAGMVA VWCLPRLHAM
260 270 280 290 300
MHQMKNPVLV LGIGGFILGI LGVIGGPVSL FKGLDEMQQM VANQAFSTSD
310 320 330 340 350
YFLLAVIKLA ALVVAAASGF RGGRIFPAVF VGVALGLMLH EHVPAVPAAI
360 370 380 390 400
TVSCAILGIV LVVTRDGWLS LFMAAVVVPN TTLLPLLCIV MLPAWLLLAG
410
KPMMMVNRPK QQPPHDNV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75448.1 AP009048 Genomic DNA Translation: BAE76708.1 |
PIRi | B65013 |
RefSeqi | NP_416890.1, NC_000913.3 WP_000903148.1, NZ_SSUW01000001.1 |
Genome annotation databases
EnsemblBacteriai | AAC75448; AAC75448; b2389 BAE76708; BAE76708; BAE76708 |
GeneIDi | 57728286 946854 |
KEGGi | ecj:JW2386 eco:b2389 |
PATRICi | fig|1411691.4.peg.4339 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC75448.1 AP009048 Genomic DNA Translation: BAE76708.1 |
PIRi | B65013 |
RefSeqi | NP_416890.1, NC_000913.3 WP_000903148.1, NZ_SSUW01000001.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4259181, 309 interactors |
STRINGi | 511145.b2389 |
Proteomic databases
PaxDbi | P67729 |
PRIDEi | P67729 |
Genome annotation databases
EnsemblBacteriai | AAC75448; AAC75448; b2389 BAE76708; BAE76708; BAE76708 |
GeneIDi | 57728286 946854 |
KEGGi | ecj:JW2386 eco:b2389 |
PATRICi | fig|1411691.4.peg.4339 |
Organism-specific databases
EchoBASEi | EB3908 |
Phylogenomic databases
eggNOGi | COG0038, Bacteria |
HOGENOMi | CLU_053130_0_0_6 |
InParanoidi | P67729 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7251-MONOMER |
Miscellaneous databases
PROi | PR:P67729 |
Family and domain databases
Gene3Di | 1.10.3080.10, 1 hit |
HAMAPi | MF_01115, CLC_YfeO, 1 hit |
InterProi | View protein in InterPro IPR022969, Chloride_channel_YfeO IPR014743, Cl-channel_core IPR001807, Cl-channel_volt-gated |
Pfami | View protein in Pfam PF00654, Voltage_CLC, 1 hit |
PRINTSi | PR00762, CLCHANNEL |
SUPFAMi | SSF81340, SSF81340, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YFEO_ECOLI | |
Accessioni | P67729Primary (citable) accession number: P67729 Secondary accession number(s): P76526, Q2MAJ8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 11, 2004 |
Last sequence update: | October 11, 2004 | |
Last modified: | February 10, 2021 | |
This is version 104 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families