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Protein

Protein RecA

Gene

recA

Organism
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi69 – 76ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA recombination, DNA repair, SOS response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
Ordered Locus Names:TWT_611
OrganismiTropheryma whipplei (strain Twist) (Whipple's bacillus)
Taxonomic identifieri203267 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesTropheryma
Proteomesi
  • UP000002200 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001228871 – 437Protein RecAAdd BLAST437

Proteomic databases

PRIDEiP65981

Interactioni

Protein-protein interaction databases

STRINGi203267.TWT611

Structurei

3D structure databases

ProteinModelPortaliP65981
SMRiP65981
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C68 Bacteria
COG0468 LUCA
KOiK03553
OMAiSKMGLQA
OrthoDBiPOG091H01OP

Family and domain databases

CDDicd00983 recA, 1 hit
Gene3Di3.30.250.10, 1 hit
HAMAPiMF_00268 RecA, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013765 DNA_recomb/repair_RecA
IPR020584 DNA_recomb/repair_RecA_CS
IPR027417 P-loop_NTPase
IPR020588 RecA_ATP-bd
IPR023400 RecA_C
IPR020587 RecA_monomer-monomer_interface
PANTHERiPTHR22942:SF1 PTHR22942:SF1, 1 hit
PfamiView protein in Pfam
PF00154 RecA, 1 hit
PRINTSiPR00142 RECA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF54752 SSF54752, 1 hit
TIGRFAMsiTIGR02012 tigrfam_recA, 1 hit
PROSITEiView protein in PROSITE
PS00321 RECA_1, 1 hit
PS50162 RECA_2, 1 hit
PS50163 RECA_3, 1 hit

Sequencei

Sequence statusi: Complete.

P65981-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSNDQINRT RALELALANI DRQYGKGAVM RMNDAQKAYI DVIPTGSIAL
60 70 80 90 100
DYALGVGGLP RGRIVEIYGP ESSGKTTLTL HAIASVQRAG GIAAFIDAEH
110 120 130 140 150
ALDPEYAKKL GVDIDALLVS QPDSGEQALE ISDMLIRSTA IDLIVIDSVA
160 170 180 190 200
ALVPRAELEG DMGDMHVGLQ ARLMSQALRK ITSGLNQTGT TAIFINQLRE
210 220 230 240 250
KVGVFFGSPE TTPGGRALKF YASVRLDIRR VETIKQGTEA VGNRTRVKVV
260 270 280 290 300
KNKVAPPFKQ AEFDVLYGVG ISRESGLIDF AVDRGIIKKS GSWYVYGDDQ
310 320 330 340 350
LGQGKENARR FLLENKSVAD EIENKIISLL GFRSNEFGDL PDHDAAVRTS
360 370 380 390 400
PDTNSRKVSG TGAVHTTSGS PSAGKGTASG AVNNSRDSTG GDTPAGQGPL
410 420 430
NLSVNRDVST DTVSSKISDA THNQKPAGNG KSVKRKG
Length:437
Mass (Da):46,450
Last modified:October 11, 2004 - v1
Checksum:i969186E5C5F390D8
GO

Sequence cautioni

The sequence AAO44708 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014184 Genomic DNA Translation: AAO44708.1 Different initiation.
RefSeqiWP_011096570.1, NC_004572.3

Genome annotation databases

EnsemblBacteriaiAAO44708; AAO44708; TWT_611
GeneIDi29577834
KEGGitwh:TWT_611

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014184 Genomic DNA Translation: AAO44708.1 Different initiation.
RefSeqiWP_011096570.1, NC_004572.3

3D structure databases

ProteinModelPortaliP65981
SMRiP65981
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203267.TWT611

Proteomic databases

PRIDEiP65981

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO44708; AAO44708; TWT_611
GeneIDi29577834
KEGGitwh:TWT_611

Phylogenomic databases

eggNOGiENOG4105C68 Bacteria
COG0468 LUCA
KOiK03553
OMAiSKMGLQA
OrthoDBiPOG091H01OP

Family and domain databases

CDDicd00983 recA, 1 hit
Gene3Di3.30.250.10, 1 hit
HAMAPiMF_00268 RecA, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013765 DNA_recomb/repair_RecA
IPR020584 DNA_recomb/repair_RecA_CS
IPR027417 P-loop_NTPase
IPR020588 RecA_ATP-bd
IPR023400 RecA_C
IPR020587 RecA_monomer-monomer_interface
PANTHERiPTHR22942:SF1 PTHR22942:SF1, 1 hit
PfamiView protein in Pfam
PF00154 RecA, 1 hit
PRINTSiPR00142 RECA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF54752 SSF54752, 1 hit
TIGRFAMsiTIGR02012 tigrfam_recA, 1 hit
PROSITEiView protein in PROSITE
PS00321 RECA_1, 1 hit
PS50162 RECA_2, 1 hit
PS50163 RECA_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRECA_TROWT
AccessioniPrimary (citable) accession number: P65981
Secondary accession number(s): Q83MS9, Q83NC6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: October 10, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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