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UniProtKB - P63938 (ALDH_MYCBO)
Protein
Probable aldehyde dehydrogenase
Gene
BQ2027_MB0467
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Functioni
Catalytic activityi
- EC:1.2.1.3
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 263 | By similarity | 1 | |
Active sitei | 302 | By similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 219 – 225 | NADBy similarity | 7 |
GO - Molecular functioni
- aldehyde dehydrogenase (NAD+) activity Source: UniProtKB-EC
- glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity Source: UniProtKB-EC
Keywordsi
Molecular function | Oxidoreductase |
Ligand | NAD |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:BQ2027_MB0467 |
Organismi | Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) |
Taxonomic identifieri | 233413 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000056450 | 1 – 507 | Probable aldehyde dehydrogenaseAdd BLAST | 507 |
Family & Domainsi
Sequence similaritiesi
Belongs to the aldehyde dehydrogenase family.Curated
Phylogenomic databases
OMAi | ILMGAWK |
Family and domain databases
Gene3Di | 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit |
SUPFAMi | SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit |
i Sequence
Sequence statusi: Complete.
P63938-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTVFSRPGSA GALMSYESRY QNFIGGQWVA PVHGRYFENP TPVTGQPFCE
60 70 80 90 100
VPRSDAADID KALDAAHAAA PGWGKTAPAE RAAILNMIAD RIDKNAAALA
110 120 130 140 150
VAEVWDNGKP VREALAADIP LAVDHFRYFA AAIRAQEGAL SQIDEDTVAY
160 170 180 190 200
HFHEPLGVVG QIIPWNFPIL MAAWKLAPAL AAGNTAVLKP AEQTPASVLY
210 220 230 240 250
LMSLIGDLLP PGVVNVVNGF GAEAGKPLAS SDRIAKVAFT GETTTGRLIM
260 270 280 290 300
QYASHNLIPV TLELGGKSPN IFFADVLAAH DDFCDKALEG FTMFALNQGE
310 320 330 340 350
VCTCPSRSLI QADIYDEFLE LAAIRTKAVR QGDPLDTETM LGSQASNDQL
360 370 380 390 400
EKVLSYIEIG KQEGAVIIAG GERAELGGDL SGGYYMQPTI FTGTNNMRIF
410 420 430 440 450
KEEIFGPVVA VTSFTDYDDA IGIANDTLYG LGAGVWSRDG NTAYRAGRDI
460 470 480 490 500
QAGRVWVNCY HLYPAHAAFG GYKQSGIGRE GHQMMLQHYQ HTKNLLVSYS
DKALGFF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LT708304 Genomic DNA Translation: SIT99061.1 |
RefSeqi | NP_854130.1, NC_002945.3 WP_003402294.1, NC_002945.4 |
Genome annotation databases
GeneIDi | 45424420 |
PATRICi | fig|233413.5.peg.509 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LT708304 Genomic DNA Translation: SIT99061.1 |
RefSeqi | NP_854130.1, NC_002945.3 WP_003402294.1, NC_002945.4 |
3D structure databases
AlphaFoldDBi | P63938 |
SMRi | P63938 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 45424420 |
PATRICi | fig|233413.5.peg.509 |
Phylogenomic databases
OMAi | ILMGAWK |
Family and domain databases
Gene3Di | 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit |
SUPFAMi | SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ALDH_MYCBO | |
Accessioni | P63938Primary (citable) accession number: P63938 Secondary accession number(s): A0A1R3XXK2, O53743, X2BF41 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 11, 2004 |
Last sequence update: | October 11, 2004 | |
Last modified: | May 25, 2022 | |
This is version 100 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |