UniProtKB - P63389 (YHES_ECOLI)
Protein
Probable ATP-binding protein YheS
Gene
yheS
Organism
Escherichia coli (strain K12)
Status
Functioni
Genetic data indicate it may be involved in ribosome assembly or function.1 Publication
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 34 – 41 | ATP 1PROSITE-ProRule annotation | 8 | |
Nucleotide bindingi | 345 – 352 | ATP 2PROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: EcoCyc
Keywordsi
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:YHES-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Probable ATP-binding protein YheS |
Gene namesi | Name:yheS Ordered Locus Names:b3352, JW3315 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Pathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 175 | E → Q: Causes growth defect at 37 degrees Celsius, 7-fold decrease in translation; when associated with Q-456 (called EQ2). 1 Publication | 1 | |
Mutagenesisi | 456 | E → Q: Causes growth defect at 37 degrees Celsius, 7-fold decrease in translation; when associated with Q-175 (EQ2). 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000093187 | 1 – 637 | Probable ATP-binding protein YheSAdd BLAST | 637 |
Proteomic databases
jPOSTi | P63389 |
PaxDbi | P63389 |
PRIDEi | P63389 |
Interactioni
Binary interactionsi
Hide detailsProtein-protein interaction databases
BioGRIDi | 4260997, 19 interactors 852167, 6 interactors |
DIPi | DIP-48200N |
IntActi | P63389, 11 interactors |
STRINGi | 511145.b3352 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 246 | ABC transporter 1PROSITE-ProRule annotationAdd BLAST | 245 | |
Domaini | 313 – 527 | ABC transporter 2PROSITE-ProRule annotationAdd BLAST | 215 |
Sequence similaritiesi
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG0488, Bacteria |
HOGENOMi | CLU_000604_36_0_6 |
InParanoidi | P63389 |
PhylomeDBi | P63389 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR032781, ABC_tran_Xtn IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits PF12848, ABC_tran_Xtn, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 2 hits |
i Sequence
Sequence statusi: Complete.
P63389-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIVFSSLQIR RGVRVLLDNA TATINPGQKV GLVGKNGCGK STLLALLKNE
60 70 80 90 100
ISADGGSYTF PGSWQLAWVN QETPALPQAA LEYVIDGDRE YRQLEAQLHD
110 120 130 140 150
ANERNDGHAI ATIHGKLDAI DAWSIRSRAA SLLHGLGFSN EQLERPVSDF
160 170 180 190 200
SGGWRMRLNL AQALICRSDL LLLDEPTNHL DLDAVIWLEK WLKSYQGTLI
210 220 230 240 250
LISHDRDFLD PIVDKIIHIE QQSMFEYTGN YSSFEVQRAT RLAQQQAMYE
260 270 280 290 300
SQQERVAHLQ SYIDRFRAKA TKAKQAQSRI KMLERMELIA PAHVDNPFRF
310 320 330 340 350
SFRAPESLPN PLLKMEKVSA GYGDRIILDS IKLNLVPGSR IGLLGRNGAG
360 370 380 390 400
KSTLIKLLAG ELAPVSGEIG LAKGIKLGYF AQHQLEYLRA DESPIQHLAR
410 420 430 440 450
LAPQELEQKL RDYLGGFGFQ GDKVTEETRR FSGGEKARLV LALIVWQRPN
460 470 480 490 500
LLLLDEPTNH LDLDMRQALT EALIEFEGAL VVVSHDRHLL RSTTDDLYLV
510 520 530 540 550
HDRKVEPFDG DLEDYQQWLS DVQKQENQTD EAPKENANSA QARKDQKRRE
560 570 580 590 600
AELRAQTQPL RKEIARLEKE MEKLNAQLAQ AEEKLGDSEL YDQSRKAELT
610 620 630
ACLQQQASAK SGLEECEMAW LEAQEQLEQM LLEGQSN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U18997 Genomic DNA Translation: AAA58149.1 U00096 Genomic DNA Translation: AAC76377.1 AP009048 Genomic DNA Translation: BAE77938.1 |
PIRi | C65129 |
RefSeqi | NP_417811.1, NC_000913.3 WP_000634798.1, NZ_SSZK01000008.1 |
Genome annotation databases
EnsemblBacteriai | AAC76377; AAC76377; b3352 BAE77938; BAE77938; BAE77938 |
GeneIDi | 947856 |
KEGGi | ecj:JW3315 eco:b3352 |
PATRICi | fig|1411691.4.peg.3378 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U18997 Genomic DNA Translation: AAA58149.1 U00096 Genomic DNA Translation: AAC76377.1 AP009048 Genomic DNA Translation: BAE77938.1 |
PIRi | C65129 |
RefSeqi | NP_417811.1, NC_000913.3 WP_000634798.1, NZ_SSZK01000008.1 |
3D structure databases
SMRi | P63389 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260997, 19 interactors 852167, 6 interactors |
DIPi | DIP-48200N |
IntActi | P63389, 11 interactors |
STRINGi | 511145.b3352 |
Proteomic databases
jPOSTi | P63389 |
PaxDbi | P63389 |
PRIDEi | P63389 |
Genome annotation databases
EnsemblBacteriai | AAC76377; AAC76377; b3352 BAE77938; BAE77938; BAE77938 |
GeneIDi | 947856 |
KEGGi | ecj:JW3315 eco:b3352 |
PATRICi | fig|1411691.4.peg.3378 |
Organism-specific databases
EchoBASEi | EB2740 |
Phylogenomic databases
eggNOGi | COG0488, Bacteria |
HOGENOMi | CLU_000604_36_0_6 |
InParanoidi | P63389 |
PhylomeDBi | P63389 |
Enzyme and pathway databases
BioCyci | EcoCyc:YHES-MONOMER |
Miscellaneous databases
PROi | PR:P63389 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR032781, ABC_tran_Xtn IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits PF12848, ABC_tran_Xtn, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YHES_ECOLI | |
Accessioni | P63389Primary (citable) accession number: P63389 Secondary accession number(s): P45535, Q2M718 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 11, 2004 |
Last sequence update: | October 11, 2004 | |
Last modified: | December 2, 2020 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families