UniProtKB - P62907 (RL10A_RAT)
Protein
60S ribosomal protein L10a
Gene
Rpl10a
Organism
Rattus norvegicus (Rat)
Status
Functioni
Component of the large ribosomal subunit.By similarity
GO - Molecular functioni
- RNA binding Source: GO_Central
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- cytoplasmic translation Source: RGD
- maturation of LSU-rRNA Source: GO_Central
- response to ethanol Source: RGD
- translation Source: RGD
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-RNO-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-RNO-1799339, SRP-dependent cotranslational protein targeting to membrane R-RNO-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-RNO-72689, Formation of a pool of free 40S subunits R-RNO-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-RNO-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-RNO-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Names & Taxonomyi
Protein namesi | Recommended name: 60S ribosomal protein L10a |
Gene namesi | Name:Rpl10a |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 620497, Rpl10a |
Subcellular locationi
Cytosol
- cytosolic large ribosomal subunit Source: RGD
Other locations
- polysomal ribosome Source: RGD
- synapse Source: RGD
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000125822 | 2 – 217 | 60S ribosomal protein L10aAdd BLAST | 216 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserineBy similarity | 1 | |
Modified residuei | 11 | PhosphotyrosineBy similarity | 1 | |
Modified residuei | 91 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 106 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 118 | N6-acetyllysine; alternateBy similarity | 1 | |
Cross-linki | 118 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity | ||
Cross-linki | 118 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity | ||
Cross-linki | 161 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
jPOSTi | P62907 |
PaxDbi | P62907 |
PRIDEi | P62907 |
PTM databases
iPTMneti | P62907 |
PhosphoSitePlusi | P62907 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000000505, Expressed in thymus and 20 other tissues |
Genevisiblei | P62907, RN |
Interactioni
Subunit structurei
Component of the large ribosomal subunit.
By similarityProtein-protein interaction databases
BioGRIDi | 249602, 2 interactors |
IntActi | P62907, 3 interactors |
STRINGi | 10116.ENSRNOP00000000603 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL1 family.Curated
Phylogenomic databases
eggNOGi | KOG1570, Eukaryota |
GeneTreei | ENSGT00390000008767 |
HOGENOMi | CLU_062853_3_0_1 |
InParanoidi | P62907 |
OMAi | TMAINFL |
OrthoDBi | 1172076at2759 |
PhylomeDBi | P62907 |
TreeFami | TF300791 |
Family and domain databases
CDDi | cd00403, Ribosomal_L1, 1 hit |
Gene3Di | 3.40.50.790, 1 hit |
InterProi | View protein in InterPro IPR002143, Ribosomal_L1 IPR023674, Ribosomal_L1-like IPR028364, Ribosomal_L1/biogenesis IPR016095, Ribosomal_L1_3-a/b-sand IPR023673, Ribosomal_L1_CS |
Pfami | View protein in Pfam PF00687, Ribosomal_L1, 1 hit |
PIRSFi | PIRSF002155, Ribosomal_L1, 1 hit |
SUPFAMi | SSF56808, SSF56808, 1 hit |
PROSITEi | View protein in PROSITE PS01199, RIBOSOMAL_L1, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P62907-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSKVSRDTL YEAVREVLHG NQRKRRKFLE TVELQISLKN YDPQKDKRFS
60 70 80 90 100
GTVRLKSTPR PKFSVCVLGD QQHCDEAKAV DIPHMDIEAL KKLNKNKKLV
110 120 130 140 150
KKLAKKYDAF LASESLIKQI PRILGPGLNK AGKFPSLLTH NENMVAKVDE
160 170 180 190 200
VKSTIKFQMK KVLCLAVAVG HVKMTDDELV YNIHLAVNFL VSLLKKNWQN
210
VRALYIKSTM GKPQRLY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X93352 mRNA Translation: CAA63732.1 BC058468 mRNA Translation: AAH58468.1 |
PIRi | JC4677 |
RefSeqi | NP_112327.1, NM_031065.1 |
Genome annotation databases
Ensembli | ENSRNOT00000000603; ENSRNOP00000000603; ENSRNOG00000000505 |
GeneIDi | 81729 |
KEGGi | rno:81729 |
UCSCi | RGD:620497, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X93352 mRNA Translation: CAA63732.1 BC058468 mRNA Translation: AAH58468.1 |
PIRi | JC4677 |
RefSeqi | NP_112327.1, NM_031065.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 249602, 2 interactors |
IntActi | P62907, 3 interactors |
STRINGi | 10116.ENSRNOP00000000603 |
PTM databases
iPTMneti | P62907 |
PhosphoSitePlusi | P62907 |
Proteomic databases
jPOSTi | P62907 |
PaxDbi | P62907 |
PRIDEi | P62907 |
Genome annotation databases
Ensembli | ENSRNOT00000000603; ENSRNOP00000000603; ENSRNOG00000000505 |
GeneIDi | 81729 |
KEGGi | rno:81729 |
UCSCi | RGD:620497, rat |
Organism-specific databases
CTDi | 4736 |
RGDi | 620497, Rpl10a |
Phylogenomic databases
eggNOGi | KOG1570, Eukaryota |
GeneTreei | ENSGT00390000008767 |
HOGENOMi | CLU_062853_3_0_1 |
InParanoidi | P62907 |
OMAi | TMAINFL |
OrthoDBi | 1172076at2759 |
PhylomeDBi | P62907 |
TreeFami | TF300791 |
Enzyme and pathway databases
Reactomei | R-RNO-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-RNO-1799339, SRP-dependent cotranslational protein targeting to membrane R-RNO-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-RNO-72689, Formation of a pool of free 40S subunits R-RNO-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-RNO-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-RNO-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Miscellaneous databases
PROi | PR:P62907 |
Gene expression databases
Bgeei | ENSRNOG00000000505, Expressed in thymus and 20 other tissues |
Genevisiblei | P62907, RN |
Family and domain databases
CDDi | cd00403, Ribosomal_L1, 1 hit |
Gene3Di | 3.40.50.790, 1 hit |
InterProi | View protein in InterPro IPR002143, Ribosomal_L1 IPR023674, Ribosomal_L1-like IPR028364, Ribosomal_L1/biogenesis IPR016095, Ribosomal_L1_3-a/b-sand IPR023673, Ribosomal_L1_CS |
Pfami | View protein in Pfam PF00687, Ribosomal_L1, 1 hit |
PIRSFi | PIRSF002155, Ribosomal_L1, 1 hit |
SUPFAMi | SSF56808, SSF56808, 1 hit |
PROSITEi | View protein in PROSITE PS01199, RIBOSOMAL_L1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL10A_RAT | |
Accessioni | P62907Primary (citable) accession number: P62907 Secondary accession number(s): P52859, P53025 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 31, 2004 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 125 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries