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Entry version 159 (16 Oct 2019)
Sequence version 2 (23 Jan 2007)
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Protein

60S ribosomal protein L10a

Gene

RPL10A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the large ribosomal subunit.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L10a
Alternative name(s):
CSA-19
Large ribosomal subunit protein uL11 Publication
Neural precursor cell expressed developmentally down-regulated protein 6
Short name:
NEDD-6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPL10A
Synonyms:NEDD6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10299 RPL10A

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615660 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P62906

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
4736

Open Targets

More...
OpenTargetsi
ENSG00000198755

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34661

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P62906

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPL10A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
51702773

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001258182 – 21760S ribosomal protein L10aAdd BLAST216

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserine1 Publication1
Modified residuei11PhosphotyrosineBy similarity1
Modified residuei91N6-acetyllysineBy similarity1
Modified residuei106N6-acetyllysineCombined sources1
Modified residuei118N6-acetyllysine; alternateCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki118Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linki118Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Cross-linki161Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P62906

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P62906

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P62906

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P62906

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P62906

PeptideAtlas

More...
PeptideAtlasi
P62906

PRoteomics IDEntifications database

More...
PRIDEi
P62906

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
57450

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P62906

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

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SWISS-2DPAGEi
P62906

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P62906

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P62906

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P62906

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198755 Expressed in 88 organ(s), highest expression level in right uterine tube

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P62906 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA053803

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the large ribosomal subunit.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
110813, 227 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P62906

Protein interaction database and analysis system

More...
IntActi
P62906, 97 interactors

Molecular INTeraction database

More...
MINTi
P62906

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000363018

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P62906

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1570 Eukaryota
COG0081 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008767

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000207014

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P62906

KEGG Orthology (KO)

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KOi
K02865

Identification of Orthologs from Complete Genome Data

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OMAi
PKFSVCL

Database of Orthologous Groups

More...
OrthoDBi
1172076at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P62906

TreeFam database of animal gene trees

More...
TreeFami
TF300791

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00403 Ribosomal_L1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.40.50.790, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR002143 Ribosomal_L1
IPR023674 Ribosomal_L1-like
IPR028364 Ribosomal_L1/biogenesis
IPR016095 Ribosomal_L1_3-a/b-sand
IPR023673 Ribosomal_L1_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00687 Ribosomal_L1, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002155 Ribosomal_L1, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF56808 SSF56808, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01199 RIBOSOMAL_L1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P62906-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSKVSRDTL YEAVREVLHG NQRKRRKFLE TVELQISLKN YDPQKDKRFS
60 70 80 90 100
GTVRLKSTPR PKFSVCVLGD QQHCDEAKAV DIPHMDIEAL KKLNKNKKLV
110 120 130 140 150
KKLAKKYDAF LASESLIKQI PRILGPGLNK AGKFPSLLTH NENMVAKVDE
160 170 180 190 200
VKSTIKFQMK KVLCLAVAVG HVKMTDDELV YNIHLAVNFL VSLLKKNWQN
210
VRALYIKSTM GKPQRLY
Length:217
Mass (Da):24,831
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i38F1A31119A751D3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti104A → V in AAA86463 (PubMed:7609734).Curated1
Sequence conflicti209T → P in BAC16802 (Ref. 2) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_034458154T → P. Corresponds to variant dbSNP:rs17838763Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
U12404 mRNA Translation: AAA86463.1
AB082926 mRNA Translation: BAC16802.1
BT020040 mRNA Translation: AAV38843.1
BT020041 mRNA Translation: AAV38844.1
AK313181 mRNA Translation: BAG35998.1
AL022721 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03831.1
BC006791 mRNA Translation: AAH06791.1
BC011366 mRNA Translation: AAH11366.1
BC070216 mRNA Translation: AAH70216.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4806.1

NCBI Reference Sequences

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RefSeqi
NP_009035.3, NM_007104.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000322203; ENSP00000363018; ENSG00000198755

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4736

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:4736

UCSC genome browser

More...
UCSCi
uc003okp.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12404 mRNA Translation: AAA86463.1
AB082926 mRNA Translation: BAC16802.1
BT020040 mRNA Translation: AAV38843.1
BT020041 mRNA Translation: AAV38844.1
AK313181 mRNA Translation: BAG35998.1
AL022721 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03831.1
BC006791 mRNA Translation: AAH06791.1
BC011366 mRNA Translation: AAH11366.1
BC070216 mRNA Translation: AAH70216.1
CCDSiCCDS4806.1
RefSeqiNP_009035.3, NM_007104.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-Lz1-217[»]
4V6Xelectron microscopy5.00Cz1-217[»]
5AJ0electron microscopy3.50Au1-217[»]
5LKSelectron microscopy3.60Lz1-217[»]
5T2Celectron microscopy3.60l1-217[»]
6EK0electron microscopy2.90Lz1-217[»]
6IP5electron microscopy3.902l1-217[»]
6OLGelectron microscopy3.40Au1-217[»]
6QZPelectron microscopy2.90Lz1-217[»]
SMRiP62906
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi110813, 227 interactors
CORUMiP62906
IntActiP62906, 97 interactors
MINTiP62906
STRINGi9606.ENSP00000363018

PTM databases

iPTMnetiP62906
PhosphoSitePlusiP62906
SwissPalmiP62906

Polymorphism and mutation databases

BioMutaiRPL10A
DMDMi51702773

2D gel databases

SWISS-2DPAGEiP62906

Proteomic databases

EPDiP62906
jPOSTiP62906
MassIVEiP62906
MaxQBiP62906
PaxDbiP62906
PeptideAtlasiP62906
PRIDEiP62906
ProteomicsDBi57450
TopDownProteomicsiP62906

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
4736

Genome annotation databases

EnsembliENST00000322203; ENSP00000363018; ENSG00000198755
GeneIDi4736
KEGGihsa:4736
UCSCiuc003okp.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4736
DisGeNETi4736

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RPL10A
HGNCiHGNC:10299 RPL10A
HPAiHPA053803
MIMi615660 gene
neXtProtiNX_P62906
OpenTargetsiENSG00000198755
PharmGKBiPA34661

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1570 Eukaryota
COG0081 LUCA
GeneTreeiENSGT00390000008767
HOGENOMiHOG000207014
InParanoidiP62906
KOiK02865
OMAiPKFSVCL
OrthoDBi1172076at2759
PhylomeDBiP62906
TreeFamiTF300791

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RPL10A human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
RPL10A

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
4736
PharosiP62906

Protein Ontology

More...
PROi
PR:P62906

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000198755 Expressed in 88 organ(s), highest expression level in right uterine tube
GenevisibleiP62906 HS

Family and domain databases

CDDicd00403 Ribosomal_L1, 1 hit
Gene3Di3.40.50.790, 1 hit
InterProiView protein in InterPro
IPR002143 Ribosomal_L1
IPR023674 Ribosomal_L1-like
IPR028364 Ribosomal_L1/biogenesis
IPR016095 Ribosomal_L1_3-a/b-sand
IPR023673 Ribosomal_L1_CS
PfamiView protein in Pfam
PF00687 Ribosomal_L1, 1 hit
PIRSFiPIRSF002155 Ribosomal_L1, 1 hit
SUPFAMiSSF56808 SSF56808, 1 hit
PROSITEiView protein in PROSITE
PS01199 RIBOSOMAL_L1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL10A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62906
Secondary accession number(s): B2R801
, P52859, P53025, Q5TZT6, Q8J013
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: January 23, 2007
Last modified: October 16, 2019
This is version 159 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  7. Ribosomal proteins
    Ribosomal proteins families and list of entries
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