UniProtKB - P62900 (RL31_MOUSE)
Protein
60S ribosomal protein L31
Gene
Rpl31
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- structural constituent of ribosome Source: GO_Central
GO - Biological processi
- cytoplasmic translation Source: MGI
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-MMU-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-MMU-1799339, SRP-dependent cotranslational protein targeting to membrane R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-MMU-72689, Formation of a pool of free 40S subunits R-MMU-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-MMU-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-MMU-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Names & Taxonomyi
Protein namesi | Recommended name: 60S ribosomal protein L31 |
Gene namesi | Name:Rpl31 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2149632, Rpl31 |
Subcellular locationi
Cytosol
- cytosol Source: Reactome
- cytosolic large ribosomal subunit Source: MGI
Nucleus
- nucleolus Source: MGI
- nucleoplasm Source: MGI
Other locations
- polysomal ribosome Source: MGI
- synapse Source: SynGO
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000153764 | 1 – 125 | 60S ribosomal protein L31Add BLAST | 125 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineBy similarity | 1 | |
Modified residuei | 15 | PhosphoserineCombined sources | 1 | |
Modified residuei | 55 | N6-succinyllysineCombined sources | 1 | |
Modified residuei | 70 | N6-succinyllysineCombined sources | 1 | |
Modified residuei | 75 | N6-acetyllysine; alternateBy similarity | 1 | |
Modified residuei | 75 | N6-succinyllysine; alternateCombined sources | 1 | |
Modified residuei | 98 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | P62900 |
jPOSTi | P62900 |
PaxDbi | P62900 |
PeptideAtlasi | P62900 |
PRIDEi | P62900 |
ProteomicsDBi | 253251 |
PTM databases
iPTMneti | P62900 |
PhosphoSitePlusi | P62900 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000073702, Expressed in thymus and 280 other tissues |
Genevisiblei | P62900, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 227776, 80 interactors |
ComplexPortali | CPX-5262, 60S cytosolic large ribosomal subunit |
IntActi | P62900, 10 interactors |
MINTi | P62900 |
STRINGi | 10090.ENSMUSP00000137631 |
Miscellaneous databases
RNActi | P62900, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the eukaryotic ribosomal protein eL31 family.Curated
Phylogenomic databases
eggNOGi | KOG0893, Eukaryota |
GeneTreei | ENSGT00950000183030 |
HOGENOMi | CLU_112570_1_1_1 |
InParanoidi | P62900 |
OMAi | EMGTNDV |
OrthoDBi | 1547011at2759 |
PhylomeDBi | P62900 |
TreeFami | TF314858 |
Family and domain databases
CDDi | cd00463, Ribosomal_L31e, 1 hit |
Gene3Di | 3.10.440.10, 1 hit |
InterProi | View protein in InterPro IPR000054, Ribosomal_L31e IPR020052, Ribosomal_L31e_CS IPR023621, Ribosomal_L31e_dom_sf |
PANTHERi | PTHR10956, PTHR10956, 1 hit |
Pfami | View protein in Pfam PF01198, Ribosomal_L31e, 1 hit |
SMARTi | View protein in SMART SM01380, Ribosomal_L31e, 1 hit |
SUPFAMi | SSF54575, SSF54575, 1 hit |
PROSITEi | View protein in PROSITE PS01144, RIBOSOMAL_L31E, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
P62900-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR
60 70 80 90 100
KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLSR KRNEDEDSPN
110 120
KLYTLVTYVP VTTFKNLQTV NVDEN
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A0A6YXL3 | A0A0A6YXL3_MOUSE | 60S ribosomal protein L31 | Rpl31 | 87 | Annotation score: | ||
A0A0A6YX26 | A0A0A6YX26_MOUSE | 60S ribosomal protein L31 | Rpl31 | 129 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF362574 mRNA Translation: AAK70404.1 AK011236 mRNA Translation: BAB27484.1 AK014295 mRNA Translation: BAB29251.1 AK020627 mRNA Translation: BAB32156.1 BC008223 mRNA No translation available. BC050113 mRNA Translation: AAH50113.1 BC055720 mRNA Translation: AAH55720.1 |
CCDSi | CCDS14904.1 |
RefSeqi | NP_001239147.1, NM_001252218.1 NP_001239148.1, NM_001252219.1 NP_444487.1, NM_053257.3 |
Genome annotation databases
Ensembli | ENSMUST00000086535; ENSMUSP00000083722; ENSMUSG00000073702 ENSMUST00000178079; ENSMUSP00000136354; ENSMUSG00000073702 ENSMUST00000179954; ENSMUSP00000137631; ENSMUSG00000073702 |
GeneIDi | 114641 |
KEGGi | mmu:114641 |
UCSCi | uc007ate.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF362574 mRNA Translation: AAK70404.1 AK011236 mRNA Translation: BAB27484.1 AK014295 mRNA Translation: BAB29251.1 AK020627 mRNA Translation: BAB32156.1 BC008223 mRNA No translation available. BC050113 mRNA Translation: AAH50113.1 BC055720 mRNA Translation: AAH55720.1 |
CCDSi | CCDS14904.1 |
RefSeqi | NP_001239147.1, NM_001252218.1 NP_001239148.1, NM_001252219.1 NP_444487.1, NM_053257.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6SWA | electron microscopy | 3.10 | b | 1-125 | [»] | |
SMRi | P62900 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 227776, 80 interactors |
ComplexPortali | CPX-5262, 60S cytosolic large ribosomal subunit |
IntActi | P62900, 10 interactors |
MINTi | P62900 |
STRINGi | 10090.ENSMUSP00000137631 |
PTM databases
iPTMneti | P62900 |
PhosphoSitePlusi | P62900 |
Proteomic databases
EPDi | P62900 |
jPOSTi | P62900 |
PaxDbi | P62900 |
PeptideAtlasi | P62900 |
PRIDEi | P62900 |
ProteomicsDBi | 253251 |
Genome annotation databases
Ensembli | ENSMUST00000086535; ENSMUSP00000083722; ENSMUSG00000073702 ENSMUST00000178079; ENSMUSP00000136354; ENSMUSG00000073702 ENSMUST00000179954; ENSMUSP00000137631; ENSMUSG00000073702 |
GeneIDi | 114641 |
KEGGi | mmu:114641 |
UCSCi | uc007ate.2, mouse |
Organism-specific databases
CTDi | 6160 |
MGIi | MGI:2149632, Rpl31 |
Phylogenomic databases
eggNOGi | KOG0893, Eukaryota |
GeneTreei | ENSGT00950000183030 |
HOGENOMi | CLU_112570_1_1_1 |
InParanoidi | P62900 |
OMAi | EMGTNDV |
OrthoDBi | 1547011at2759 |
PhylomeDBi | P62900 |
TreeFami | TF314858 |
Enzyme and pathway databases
Reactomei | R-MMU-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-MMU-1799339, SRP-dependent cotranslational protein targeting to membrane R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-MMU-72689, Formation of a pool of free 40S subunits R-MMU-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-MMU-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-MMU-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Miscellaneous databases
BioGRID-ORCSi | 114641, 22 hits in 46 CRISPR screens |
ChiTaRSi | Rpl31, mouse |
PROi | PR:P62900 |
RNActi | P62900, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000073702, Expressed in thymus and 280 other tissues |
Genevisiblei | P62900, MM |
Family and domain databases
CDDi | cd00463, Ribosomal_L31e, 1 hit |
Gene3Di | 3.10.440.10, 1 hit |
InterProi | View protein in InterPro IPR000054, Ribosomal_L31e IPR020052, Ribosomal_L31e_CS IPR023621, Ribosomal_L31e_dom_sf |
PANTHERi | PTHR10956, PTHR10956, 1 hit |
Pfami | View protein in Pfam PF01198, Ribosomal_L31e, 1 hit |
SMARTi | View protein in SMART SM01380, Ribosomal_L31e, 1 hit |
SUPFAMi | SSF54575, SSF54575, 1 hit |
PROSITEi | View protein in PROSITE PS01144, RIBOSOMAL_L31E, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL31_MOUSE | |
Accessioni | P62900Primary (citable) accession number: P62900 Secondary accession number(s): P12947 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 31, 2004 |
Last sequence update: | August 31, 2004 | |
Last modified: | April 7, 2021 | |
This is version 147 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families