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UniProtKB - P62900 (RL31_MOUSE)

Entry version 147 (07 Apr 2021)
Sequence version 1 (31 Aug 2004)
Previous versions | rss
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Protein

60S ribosomal protein L31

Gene

Rpl31

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-MMU-1799339, SRP-dependent cotranslational protein targeting to membrane
R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-MMU-72689, Formation of a pool of free 40S subunits
R-MMU-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-MMU-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-MMU-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L31
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rpl31
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2149632, Rpl31

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001537641 – 12560S ribosomal protein L31Add BLAST125

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
Modified residuei15PhosphoserineCombined sources1
Modified residuei55N6-succinyllysineCombined sources1
Modified residuei70N6-succinyllysineCombined sources1
Modified residuei75N6-acetyllysine; alternateBy similarity1
Modified residuei75N6-succinyllysine; alternateCombined sources1
Modified residuei98PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P62900

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P62900

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P62900

PeptideAtlas

More...PeptideAtlasi		P62900

PRoteomics IDEntifications database

More...PRIDEi		P62900

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		253251

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P62900

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P62900

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000073702, Expressed in thymus and 280 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P62900, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		227776, 80 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-5262, 60S cytosolic large ribosomal subunit

Protein interaction database and analysis system

More...IntActi		P62900, 10 interactors

Molecular INTeraction database

More...MINTi		P62900

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000137631

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P62900, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P62900

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eL31 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0893, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183030

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_112570_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P62900

Identification of Orthologs from Complete Genome Data

More...OMAi		EMGTNDV

Database of Orthologous Groups

More...OrthoDBi		1547011at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P62900

TreeFam database of animal gene trees

More...TreeFami		TF314858

Family and domain databases

Conserved Domains Database

More...CDDi		cd00463, Ribosomal_L31e, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.440.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000054, Ribosomal_L31e
IPR020052, Ribosomal_L31e_CS
IPR023621, Ribosomal_L31e_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR10956, PTHR10956, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01198, Ribosomal_L31e, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01380, Ribosomal_L31e, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54575, SSF54575, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01144, RIBOSOMAL_L31E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P62900-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR 
        60         70         80         90        100
KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLSR KRNEDEDSPN 
       110        120 
KLYTLVTYVP VTTFKNLQTV NVDEN
Length:125
Mass (Da):14,463
Last modified:August 31, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBA9DBE79B9E1C071
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A6YXL3A0A0A6YXL3_MOUSE
60S ribosomal protein L31
Rpl31
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A6YX26A0A0A6YX26_MOUSE
60S ribosomal protein L31
Rpl31
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF362574 mRNA Translation: AAK70404.1
AK011236 mRNA Translation: BAB27484.1
AK014295 mRNA Translation: BAB29251.1
AK020627 mRNA Translation: BAB32156.1
BC008223 mRNA No translation available.
BC050113 mRNA Translation: AAH50113.1
BC055720 mRNA Translation: AAH55720.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS14904.1

NCBI Reference Sequences

More...RefSeqi		NP_001239147.1, NM_001252218.1
NP_001239148.1, NM_001252219.1
NP_444487.1, NM_053257.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000086535; ENSMUSP00000083722; ENSMUSG00000073702
ENSMUST00000178079; ENSMUSP00000136354; ENSMUSG00000073702
ENSMUST00000179954; ENSMUSP00000137631; ENSMUSG00000073702

Database of genes from NCBI RefSeq genomes

More...GeneIDi		114641

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:114641

UCSC genome browser

More...UCSCi		uc007ate.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF362574 mRNA Translation: AAK70404.1
AK011236 mRNA Translation: BAB27484.1
AK014295 mRNA Translation: BAB29251.1
AK020627 mRNA Translation: BAB32156.1
BC008223 mRNA No translation available.
BC050113 mRNA Translation: AAH50113.1
BC055720 mRNA Translation: AAH55720.1
CCDSiCCDS14904.1
RefSeqiNP_001239147.1, NM_001252218.1
NP_001239148.1, NM_001252219.1
NP_444487.1, NM_053257.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6SWAelectron microscopy3.10b1-125[»]
SMRiP62900
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi227776, 80 interactors
ComplexPortaliCPX-5262, 60S cytosolic large ribosomal subunit
IntActiP62900, 10 interactors
MINTiP62900
STRINGi10090.ENSMUSP00000137631

PTM databases

iPTMnetiP62900
PhosphoSitePlusiP62900

Proteomic databases

EPDiP62900
jPOSTiP62900
PaxDbiP62900
PeptideAtlasiP62900
PRIDEiP62900
ProteomicsDBi253251

Genome annotation databases

EnsembliENSMUST00000086535; ENSMUSP00000083722; ENSMUSG00000073702
ENSMUST00000178079; ENSMUSP00000136354; ENSMUSG00000073702
ENSMUST00000179954; ENSMUSP00000137631; ENSMUSG00000073702
GeneIDi114641
KEGGimmu:114641
UCSCiuc007ate.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		6160
MGIiMGI:2149632, Rpl31

Phylogenomic databases

eggNOGiKOG0893, Eukaryota
GeneTreeiENSGT00950000183030
HOGENOMiCLU_112570_1_1_1
InParanoidiP62900
OMAiEMGTNDV
OrthoDBi1547011at2759
PhylomeDBiP62900
TreeFamiTF314858

Enzyme and pathway databases

ReactomeiR-MMU-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-MMU-1799339, SRP-dependent cotranslational protein targeting to membrane
R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-MMU-72689, Formation of a pool of free 40S subunits
R-MMU-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-MMU-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-MMU-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		114641, 22 hits in 46 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Rpl31, mouse

Protein Ontology

More...PROi		PR:P62900
RNActiP62900, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000073702, Expressed in thymus and 280 other tissues
GenevisibleiP62900, MM

Family and domain databases

CDDicd00463, Ribosomal_L31e, 1 hit
Gene3Di3.10.440.10, 1 hit
InterProiView protein in InterPro
IPR000054, Ribosomal_L31e
IPR020052, Ribosomal_L31e_CS
IPR023621, Ribosomal_L31e_dom_sf
PANTHERiPTHR10956, PTHR10956, 1 hit
PfamiView protein in Pfam
PF01198, Ribosomal_L31e, 1 hit
SMARTiView protein in SMART
SM01380, Ribosomal_L31e, 1 hit
SUPFAMiSSF54575, SSF54575, 1 hit
PROSITEiView protein in PROSITE
PS01144, RIBOSOMAL_L31E, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL31_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62900
Secondary accession number(s): P12947
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: August 31, 2004
Last modified: April 7, 2021
This is version 147 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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