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Protein

60S ribosomal protein L31

Gene

RPL31

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • RNA binding Source: UniProtKB
  • structural constituent of ribosome Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L31
Alternative name(s):
Large ribosomal subunit protein eL311 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPL31
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000071082.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10334 RPL31

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617415 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P62899

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6160

Open Targets

More...
OpenTargetsi
ENSG00000071082

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34715

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPL31

Domain mapping of disease mutations (DMDM)

More...
DMDMi
51702807

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001537631 – 12560S ribosomal protein L31Add BLAST125

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei15PhosphoserineBy similarity1
Modified residuei55N6-succinyllysineBy similarity1
Modified residuei70N6-succinyllysineBy similarity1
Modified residuei75N6-acetyllysine; alternateCombined sources1
Modified residuei75N6-succinyllysine; alternateBy similarity1
Modified residuei98PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P62899

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P62899

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P62899

PeptideAtlas

More...
PeptideAtlasi
P62899

PRoteomics IDEntifications database

More...
PRIDEi
P62899

ProteomicsDB human proteome resource

More...
ProteomicsDBi
57447
57448 [P62899-2]
57449 [P62899-3]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P62899-1 [P62899-1]

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
P62899

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P62899

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P62899

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P62899

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000071082 Expressed in 233 organ(s), highest expression level in female gonad

CleanEx database of gene expression profiles

More...
CleanExi
HS_RPL31

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P62899 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P62899 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA072263

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112079, 162 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P62899

Protein interaction database and analysis system

More...
IntActi
P62899, 41 interactors

Molecular INTeraction database

More...
MINTi
P62899

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000386717

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P62899

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P62899

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0893 Eukaryota
COG2097 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153164

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000216660

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG001549

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P62899

KEGG Orthology (KO)

More...
KOi
K02910

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P62899

TreeFam database of animal gene trees

More...
TreeFami
TF314858

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00463 Ribosomal_L31e, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.440.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000054 Ribosomal_L31e
IPR020052 Ribosomal_L31e_CS
IPR023621 Ribosomal_L31e_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10956 PTHR10956, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01198 Ribosomal_L31e, 1 hit

ProDom; a protein domain database

More...
ProDomi
View protein in ProDom or Entries sharing at least one domain
PD006030 Ribosomal_L31e, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01380 Ribosomal_L31e, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54575 SSF54575, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01144 RIBOSOMAL_L31E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P62899-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR
60 70 80 90 100
KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLSR KRNEDEDSPN
110 120
KLYTLVTYVP VTTFKNLQTV NVDEN
Length:125
Mass (Da):14,463
Last modified:August 31, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBA9DBE79B9E1C071
GO
Isoform 2 (identifier: P62899-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     116-125: NLQTVNVDEN → ISVLNSVTVAKSP

Note: No experimental confirmation available.
Show »
Length:128
Mass (Da):14,632
Checksum:i73178D90B1AE79A8
GO
Isoform 3 (identifier: P62899-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     116-125: NLQTVNVDEN → SKFSIP

Note: No experimental confirmation available.
Show »
Length:121
Mass (Da):13,995
Checksum:iBAD3547E9019CF61
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B7Z4C8B7Z4C8_HUMAN
cDNA FLJ57527, highly similar to 60...
RPL31
130Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7Z4E3B7Z4E3_HUMAN
cDNA FLJ58908, highly similar to 60...
RPL31
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B8ZZK4B8ZZK4_HUMAN
60S ribosomal protein L31
RPL31
79Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C2W9H7C2W9_HUMAN
60S ribosomal protein L31
RPL31
108Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JU56C9JU56_HUMAN
60S ribosomal protein L31
RPL31
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_042572116 – 125NLQTVNVDEN → ISVLNSVTVAKSP in isoform 2. 1 Publication10
Alternative sequenceiVSP_043224116 – 125NLQTVNVDEN → SKFSIP in isoform 3. 1 Publication10

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X15940 mRNA Translation: CAA34066.1
AB061830 Genomic DNA Translation: BAB79468.1
AK297483 mRNA Translation: BAH12588.1
AC016738 Genomic DNA Translation: AAY14823.1
CH471127 Genomic DNA Translation: EAX01826.1
CH471127 Genomic DNA Translation: EAX01827.1
CH471127 Genomic DNA Translation: EAX01829.1
BC017343 mRNA Translation: AAH17343.1
BC070210 mRNA Translation: AAH70210.1
BC070373 mRNA Translation: AAH70373.1
X69181 mRNA Translation: CAA48925.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2049.1 [P62899-1]
CCDS46373.1 [P62899-2]
CCDS46374.1 [P62899-3]

Protein sequence database of the Protein Information Resource

More...
PIRi
S05576 R5HU31

NCBI Reference Sequences

More...
RefSeqi
NP_000984.1, NM_000993.4 [P62899-1]
NP_001092047.1, NM_001098577.2 [P62899-2]
NP_001093163.1, NM_001099693.1 [P62899-3]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.469473

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000264258; ENSP00000264258; ENSG00000071082 [P62899-1]
ENST00000409028; ENSP00000386717; ENSG00000071082 [P62899-2]
ENST00000409320; ENSP00000387163; ENSG00000071082 [P62899-3]
ENST00000409733; ENSP00000386681; ENSG00000071082 [P62899-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
6160

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6160

UCSC genome browser

More...
UCSCi
uc002taq.5 human [P62899-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15940 mRNA Translation: CAA34066.1
AB061830 Genomic DNA Translation: BAB79468.1
AK297483 mRNA Translation: BAH12588.1
AC016738 Genomic DNA Translation: AAY14823.1
CH471127 Genomic DNA Translation: EAX01826.1
CH471127 Genomic DNA Translation: EAX01827.1
CH471127 Genomic DNA Translation: EAX01829.1
BC017343 mRNA Translation: AAH17343.1
BC070210 mRNA Translation: AAH70210.1
BC070373 mRNA Translation: AAH70373.1
X69181 mRNA Translation: CAA48925.1
CCDSiCCDS2049.1 [P62899-1]
CCDS46373.1 [P62899-2]
CCDS46374.1 [P62899-3]
PIRiS05576 R5HU31
RefSeqiNP_000984.1, NM_000993.4 [P62899-1]
NP_001092047.1, NM_001098577.2 [P62899-2]
NP_001093163.1, NM_001099693.1 [P62899-3]
UniGeneiHs.469473

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-Ld1-125[»]
4V6Xelectron microscopy5.00Cd1-125[»]
5AJ0electron microscopy3.50Ad1-125[»]
5LKSelectron microscopy3.60Ld1-125[»]
5T2Celectron microscopy3.60X1-125[»]
6EK0electron microscopy2.90Ld1-125[»]
ProteinModelPortaliP62899
SMRiP62899
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi112079, 162 interactors
CORUMiP62899
IntActiP62899, 41 interactors
MINTiP62899
STRINGi9606.ENSP00000386717

PTM databases

iPTMnetiP62899
PhosphoSitePlusiP62899
SwissPalmiP62899

Polymorphism and mutation databases

BioMutaiRPL31
DMDMi51702807

2D gel databases

SWISS-2DPAGEiP62899

Proteomic databases

EPDiP62899
MaxQBiP62899
PaxDbiP62899
PeptideAtlasiP62899
PRIDEiP62899
ProteomicsDBi57447
57448 [P62899-2]
57449 [P62899-3]
TopDownProteomicsiP62899-1 [P62899-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6160
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000264258; ENSP00000264258; ENSG00000071082 [P62899-1]
ENST00000409028; ENSP00000386717; ENSG00000071082 [P62899-2]
ENST00000409320; ENSP00000387163; ENSG00000071082 [P62899-3]
ENST00000409733; ENSP00000386681; ENSG00000071082 [P62899-1]
GeneIDi6160
KEGGihsa:6160
UCSCiuc002taq.5 human [P62899-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6160
DisGeNETi6160
EuPathDBiHostDB:ENSG00000071082.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RPL31

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0017577
HGNCiHGNC:10334 RPL31
HPAiHPA072263
MIMi617415 gene
neXtProtiNX_P62899
OpenTargetsiENSG00000071082
PharmGKBiPA34715

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG0893 Eukaryota
COG2097 LUCA
GeneTreeiENSGT00940000153164
HOGENOMiHOG000216660
HOVERGENiHBG001549
InParanoidiP62899
KOiK02910
PhylomeDBiP62899
TreeFamiTF314858

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
RPL31 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
60S_ribosomal_protein_L31

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
6160

Protein Ontology

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PROi
PR:P62899

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000071082 Expressed in 233 organ(s), highest expression level in female gonad
CleanExiHS_RPL31
ExpressionAtlasiP62899 baseline and differential
GenevisibleiP62899 HS

Family and domain databases

CDDicd00463 Ribosomal_L31e, 1 hit
Gene3Di3.10.440.10, 1 hit
InterProiView protein in InterPro
IPR000054 Ribosomal_L31e
IPR020052 Ribosomal_L31e_CS
IPR023621 Ribosomal_L31e_dom_sf
PANTHERiPTHR10956 PTHR10956, 1 hit
PfamiView protein in Pfam
PF01198 Ribosomal_L31e, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD006030 Ribosomal_L31e, 1 hit
SMARTiView protein in SMART
SM01380 Ribosomal_L31e, 1 hit
SUPFAMiSSF54575 SSF54575, 1 hit
PROSITEiView protein in PROSITE
PS01144 RIBOSOMAL_L31E, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL31_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62899
Secondary accession number(s): B7Z4K2
, D3DVJ4, P12947, Q53SQ5, Q6IRZ0, Q6LBJ6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: August 31, 2004
Last modified: December 5, 2018
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  4. Ribosomal proteins
    Ribosomal proteins families and list of entries
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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