Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 171 (16 Oct 2019)
Sequence version 1 (16 Aug 2004)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

40S ribosomal protein S24

Gene

RPS24

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649 Translation initiation complex formation
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S24
Alternative name(s):
Small ribosomal subunit protein eS241 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPS24
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10411 RPS24

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
602412 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P62847

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Diamond-Blackfan anemia 3 (DBA3)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Related information in OMIM

Keywords - Diseasei

Diamond-Blackfan anemia

Organism-specific databases

DisGeNET

More...
DisGeNETi
6229

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
RPS24

MalaCards human disease database

More...
MalaCardsi
RPS24
MIMi610629 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000138326

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
124 Blackfan-Diamond anemia

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34815

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P62847

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPS24

Domain mapping of disease mutations (DMDM)

More...
DMDMi
51338645

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001376231 – 13340S ribosomal protein S24Add BLAST133

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1 Publication1
Modified residuei9PhosphothreonineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki37Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P62847

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P62847

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P62847

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P62847

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P62847

PeptideAtlas

More...
PeptideAtlasi
P62847

PRoteomics IDEntifications database

More...
PRIDEi
P62847

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
17381
57434
57435 [P62847-2]
57436 [P62847-3]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P62847-1 [P62847-1]
P62847-2 [P62847-2]
P62847-4 [P62847-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P62847

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P62847

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P62847

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mature tissues, such as adult brain, skeletal muscle, heart, and kidney, express low levels, whereas tissues and organs with significant populations of proliferating cells, such as fetal brain, placenta, bone marrow, and various glandular organs, contain significantly higher levels.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000138326 Expressed in 237 organ(s), highest expression level in zone of skin

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P62847 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P62847 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA003364

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112143, 186 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P62847

Protein interaction database and analysis system

More...
IntActi
P62847, 56 interactors

Molecular INTeraction database

More...
MINTi
P62847

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000414321

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P62847

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3424 Eukaryota
COG2004 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000153

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000186306

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P62847

KEGG Orthology (KO)

More...
KOi
K02974

Identification of Orthologs from Complete Genome Data

More...
OMAi
NWKARES

Database of Orthologous Groups

More...
OrthoDBi
664798at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P62847

TreeFam database of animal gene trees

More...
TreeFami
TF314134

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_00545 Ribosomal_S24e, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012678 Ribosomal_L23/L15e_core_dom_sf
IPR001976 Ribosomal_S24e
IPR018098 Ribosomal_S24e_CS

The PANTHER Classification System

More...
PANTHERi
PTHR10496 PTHR10496, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01282 Ribosomal_S24e, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54189 SSF54189, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00529 RIBOSOMAL_S24E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P62847-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT
60 70 80 90 100
TPDVIFVFGF RTHFGGGKTT GFGMIYDSLD YAKKNEPKHR LARHGLYEKK
110 120 130
KTSRKQRKER KNRMKKVRGT AKANVGAGKK PKE
Length:133
Mass (Da):15,423
Last modified:August 16, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCE9065C0764D60A6
GO
Isoform 2 (identifier: P62847-2) [UniParc] [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-133: Missing.

Show »
Length:130
Mass (Da):15,069
Checksum:iE0764D60A6DD576E
GO
Isoform 3 (identifier: P62847-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-133: PKE → KK

Show »
Length:132
Mass (Da):15,325
Checksum:i107190764D60A6DD
GO
Isoform 4 (identifier: P62847-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-133: PKE → MRELGLGVQA...PPSCLSGLGH

Note: No experimental confirmation available.
Show »
Length:289
Mass (Da):32,431
Checksum:i611E080AF85103CD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7ETK0E7ETK0_HUMAN
40S ribosomal protein S24
RPS24
131Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Y849A0A2R8Y849_HUMAN
40S ribosomal protein S24
RPS24
131Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8YD14A0A2R8YD14_HUMAN
40S ribosomal protein S24
RPS24 hCG_22610
165Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Y8A0A0A2R8Y8A0_HUMAN
40S ribosomal protein S24
RPS24
90Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_005724131 – 133Missing in isoform 2. 2 Publications3
Alternative sequenceiVSP_039113131 – 133PKE → KK in isoform 3. 1 Publication3
Alternative sequenceiVSP_045672131 – 133PKE → MRELGLGVQALGRISQEERC TDVKNSKARESRGVVWQVEV PGPWSVWTCGRLRRGCGKYL QVAVTWRKTENREQCCQACL LERALVRNGAFMSPASPAPA GSPHPVDGDLVLHLPEALSA TLTLSPHIQAINKSFGPFFE IHQESSCFSPPSCLSGLGH in isoform 4. 1 Publication3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M31520 mRNA Translation: AAA36588.1
U12202 Genomic DNA Translation: AAB08007.1
U12202 Genomic DNA Translation: AAB08006.1
BX336465 mRNA No translation available.
AK311776 mRNA Translation: BAG34719.1
AK311910 mRNA Translation: BAG34851.1
BX537975 mRNA Translation: CAD97939.1
AL512628 Genomic DNA No translation available.
CH471083 Genomic DNA Translation: EAW54623.1
CH471083 Genomic DNA Translation: EAW54625.1
BC000523 mRNA Translation: AAH00523.1
BC003149 mRNA No translation available.
BC071926 mRNA Translation: AAH71926.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44443.1 [P62847-4]
CCDS7355.1
CCDS7356.1 [P62847-2]
CCDS86122.1 [P62847-3]

Protein sequence database of the Protein Information Resource

More...
PIRi
JC4671
JH0213

NCBI Reference Sequences

More...
RefSeqi
NP_001017.1, NM_001026.4 [P62847-1]
NP_001135755.1, NM_001142283.1 [P62847-3]
NP_001135757.1, NM_001142285.1 [P62847-4]
NP_148982.1, NM_033022.3 [P62847-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000372360; ENSP00000361435; ENSG00000138326 [P62847-2]
ENST00000440692; ENSP00000414321; ENSG00000138326 [P62847-4]
ENST00000464716; ENSP00000494231; ENSG00000138326 [P62847-3]
ENST00000613865; ENSP00000478869; ENSG00000138326 [P62847-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6229

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6229

UCSC genome browser

More...
UCSCi
uc001jzp.4 human

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Diamond-Blackfan Anemia mutation database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31520 mRNA Translation: AAA36588.1
U12202 Genomic DNA Translation: AAB08007.1
U12202 Genomic DNA Translation: AAB08006.1
BX336465 mRNA No translation available.
AK311776 mRNA Translation: BAG34719.1
AK311910 mRNA Translation: BAG34851.1
BX537975 mRNA Translation: CAD97939.1
AL512628 Genomic DNA No translation available.
CH471083 Genomic DNA Translation: EAW54623.1
CH471083 Genomic DNA Translation: EAW54625.1
BC000523 mRNA Translation: AAH00523.1
BC003149 mRNA No translation available.
BC071926 mRNA Translation: AAH71926.1
CCDSiCCDS44443.1 [P62847-4]
CCDS7355.1
CCDS7356.1 [P62847-2]
CCDS86122.1 [P62847-3]
PIRiJC4671
JH0213
RefSeqiNP_001017.1, NM_001026.4 [P62847-1]
NP_001135755.1, NM_001142283.1 [P62847-3]
NP_001135757.1, NM_001142285.1 [P62847-4]
NP_148982.1, NM_033022.3 [P62847-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-SY1-133[»]
4V6Xelectron microscopy5.00AY1-133[»]
5A2Qelectron microscopy3.90Y1-130[»]
5AJ0electron microscopy3.50BY1-133[»]
5FLXelectron microscopy3.90Y1-133[»]
5LKSelectron microscopy3.60SY1-133[»]
5OA3electron microscopy4.30Y1-130[»]
5T2Celectron microscopy3.60AQ1-133[»]
5VYCX-ray6.00Y1/Y2/Y3/Y4/Y5/Y61-133[»]
6EK0electron microscopy2.90SY1-133[»]
6FECelectron microscopy6.30s3-133[»]
6G18electron microscopy3.60Y1-133[»]
6G4Selectron microscopy4.00Y1-133[»]
6G4Welectron microscopy4.50Y1-133[»]
6G51electron microscopy4.10Y1-133[»]
6G53electron microscopy4.50Y1-133[»]
6G5Helectron microscopy3.60Y1-133[»]
6G5Ielectron microscopy3.50Y1-133[»]
6IP5electron microscopy3.903N1-133[»]
6IP6electron microscopy4.503N1-133[»]
6IP8electron microscopy3.903N1-133[»]
6OLEelectron microscopy3.10SY2-132[»]
6OLFelectron microscopy3.90SY2-132[»]
6OLGelectron microscopy3.40BY4-128[»]
6OLIelectron microscopy3.50SY2-132[»]
6OLZelectron microscopy3.90BY4-128[»]
6OM0electron microscopy3.10SY2-132[»]
6OM7electron microscopy3.70SY2-132[»]
6QZPelectron microscopy2.90SY2-132[»]
SMRiP62847
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi112143, 186 interactors
CORUMiP62847
IntActiP62847, 56 interactors
MINTiP62847
STRINGi9606.ENSP00000414321

PTM databases

iPTMnetiP62847
PhosphoSitePlusiP62847
SwissPalmiP62847

Polymorphism and mutation databases

BioMutaiRPS24
DMDMi51338645

Proteomic databases

EPDiP62847
jPOSTiP62847
MassIVEiP62847
MaxQBiP62847
PaxDbiP62847
PeptideAtlasiP62847
PRIDEiP62847
ProteomicsDBi17381
57434
57435 [P62847-2]
57436 [P62847-3]
TopDownProteomicsiP62847-1 [P62847-1]
P62847-2 [P62847-2]
P62847-4 [P62847-4]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6229

Genome annotation databases

EnsembliENST00000372360; ENSP00000361435; ENSG00000138326 [P62847-2]
ENST00000440692; ENSP00000414321; ENSG00000138326 [P62847-4]
ENST00000464716; ENSP00000494231; ENSG00000138326 [P62847-3]
ENST00000613865; ENSP00000478869; ENSG00000138326 [P62847-1]
GeneIDi6229
KEGGihsa:6229
UCSCiuc001jzp.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6229
DisGeNETi6229

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RPS24
GeneReviewsiRPS24
HGNCiHGNC:10411 RPS24
HPAiHPA003364
MalaCardsiRPS24
MIMi602412 gene
610629 phenotype
neXtProtiNX_P62847
OpenTargetsiENSG00000138326
Orphaneti124 Blackfan-Diamond anemia
PharmGKBiPA34815

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3424 Eukaryota
COG2004 LUCA
GeneTreeiENSGT00390000000153
HOGENOMiHOG000186306
InParanoidiP62847
KOiK02974
OMAiNWKARES
OrthoDBi664798at2759
PhylomeDBiP62847
TreeFamiTF314134

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649 Translation initiation complex formation
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RPS24 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
RPS24

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
6229
PharosiP62847

Protein Ontology

More...
PROi
PR:P62847

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000138326 Expressed in 237 organ(s), highest expression level in zone of skin
ExpressionAtlasiP62847 baseline and differential
GenevisibleiP62847 HS

Family and domain databases

HAMAPiMF_00545 Ribosomal_S24e, 1 hit
InterProiView protein in InterPro
IPR012678 Ribosomal_L23/L15e_core_dom_sf
IPR001976 Ribosomal_S24e
IPR018098 Ribosomal_S24e_CS
PANTHERiPTHR10496 PTHR10496, 1 hit
PfamiView protein in Pfam
PF01282 Ribosomal_S24e, 1 hit
SUPFAMiSSF54189 SSF54189, 1 hit
PROSITEiView protein in PROSITE
PS00529 RIBOSOMAL_S24E, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS24_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62847
Secondary accession number(s): E7EPK6
, P16632, Q5T0P7, Q5T0P8, Q7Z3D1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: October 16, 2019
This is version 171 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  5. Ribosomal proteins
    Ribosomal proteins families and list of entries
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again