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Entry version 83 (26 Feb 2020)
Sequence version 2 (23 Jan 2007)
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Protein

Histone H4

Gene
N/A
Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi17 – 215

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histone H4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStrongylocentrotus purpuratus (Purple sea urchin)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7668 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007110 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome core, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001583622 – 103Histone H4Add BLAST102

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineBy similarity1
Modified residuei17N6-acetyllysineBy similarity1
Modified residuei21N6-methyllysineBy similarity1

Keywords - PTMi

Acetylation, Methylation

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P62783

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7668.SPU_028399-tr

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P62783

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the histone H4 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3467 Eukaryota
COG2036 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_109117_2_3_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P62783

KEGG Orthology (KO)

More...
KOi
K11254

Identification of Orthologs from Complete Genome Data

More...
OMAi
QKEHING

Database of Orthologous Groups

More...
OrthoDBi
1564596at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00076 H4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.20.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035425 CENP-T/H4_C
IPR009072 Histone-fold
IPR001951 Histone_H4
IPR019809 Histone_H4_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15511 CENP-T_C, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00623 HISTONEH4

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00417 H4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47113 SSF47113, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00047 HISTONE_H4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P62783-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL
60 70 80 90 100
IYEETRGVLK VFLENVIRDA VTYCEHAKRK TVTAMDVVYA LKRQGRTLYG

FGG
Length:103
Mass (Da):11,369
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA9E5DFD3F8AF04FF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X03952 Genomic DNA Translation: CAA27581.1
V01355 Genomic DNA Translation: CAA24645.1
X06639 Genomic DNA Translation: CAA29847.1
X06641 Genomic DNA Translation: CAA29849.1
M32426 mRNA Translation: AAA30054.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A02643 HSUR4P
S01618

NCBI Reference Sequences

More...
RefSeqi
NP_999707.1, NM_214542.1
NP_999713.1, NM_214548.1
NP_999715.1, NM_214550.1
NP_999716.1, NM_214551.1
XP_001175485.3, XM_001175485.3
XP_001177624.1, XM_001177624.2
XP_001178441.3, XM_001178441.3
XP_001178934.1, XM_001178934.3
XP_011661644.1, XM_011663342.1
XP_011663808.1, XM_011665506.1
XP_011678157.1, XM_011679855.1
XP_011679526.1, XM_011681224.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
SPU_000685-tr; SPU_000685-tr; SPU_000685
SPU_000768-tr; SPU_000768-tr; SPU_000768
SPU_001725-tr; SPU_001725-tr; SPU_001725
SPU_002504-tr; SPU_002504-tr; SPU_002504
SPU_002699-tr; SPU_002699-tr; SPU_002699
SPU_002794-tr; SPU_002794-tr; SPU_002794
SPU_003064-tr; SPU_003064-tr; SPU_003064
SPU_003833-tr; SPU_003833-tr; SPU_003833
SPU_004941-tr; SPU_004941-tr; SPU_004941
SPU_005173-tr; SPU_005173-tr; SPU_005173
SPU_005210-tr; SPU_005210-tr; SPU_005210
SPU_005424-tr; SPU_005424-tr; SPU_005424
SPU_005591-tr; SPU_005591-tr; SPU_005591
SPU_005704-tr; SPU_005704-tr; SPU_005704
SPU_006061-tr; SPU_006061-tr; SPU_006061
SPU_007314-tr; SPU_007314-tr; SPU_007314
SPU_007489-tr; SPU_007489-tr; SPU_007489
SPU_007705-tr; SPU_007705-tr; SPU_007705
SPU_007762-tr; SPU_007762-tr; SPU_007762
SPU_007815-tr; SPU_007815-tr; SPU_007815
SPU_007953-tr; SPU_007953-tr; SPU_007953
SPU_008489-tr; SPU_008489-tr; SPU_008489
SPU_009329-tr; SPU_009329-tr; SPU_009329
SPU_009565-tr; SPU_009565-tr; SPU_009565
SPU_010745-tr; SPU_010745-tr; SPU_010745
SPU_011273-tr; SPU_011273-tr; SPU_011273
SPU_011384-tr; SPU_011384-tr; SPU_011384
SPU_011680-tr; SPU_011680-tr; SPU_011680
SPU_011907-tr; SPU_011907-tr; SPU_011907
SPU_012107-tr; SPU_012107-tr; SPU_012107
SPU_012231-tr; SPU_012231-tr; SPU_012231
SPU_012389-tr; SPU_012389-tr; SPU_012389
SPU_012802-tr; SPU_012802-tr; SPU_012802
SPU_014878-tr; SPU_014878-tr; SPU_014878
SPU_014893-tr; SPU_014893-tr; SPU_014893
SPU_014933-tr; SPU_014933-tr; SPU_014933
SPU_015166-tr; SPU_015166-tr; SPU_015166
SPU_015201-tr; SPU_015201-tr; SPU_015201
SPU_015645-tr; SPU_015645-tr; SPU_015645
SPU_015663-tr; SPU_015663-tr; SPU_015663
SPU_015694-tr; SPU_015694-tr; SPU_015694
SPU_015742-tr; SPU_015742-tr; SPU_015742
SPU_015911-tr; SPU_015911-tr; SPU_015911
SPU_015956-tr; SPU_015956-tr; SPU_015956
SPU_016469-tr; SPU_016469-tr; SPU_016469
SPU_017482-tr; SPU_017482-tr; SPU_017482
SPU_017997-tr; SPU_017997-tr; SPU_017997
SPU_019474-tr; SPU_019474-tr; SPU_019474
SPU_019847-tr; SPU_019847-tr; SPU_019847
SPU_020454-tr; SPU_020454-tr; SPU_020454
SPU_020503-tr; SPU_020503-tr; SPU_020503
SPU_020862-tr; SPU_020862-tr; SPU_020862
SPU_021741-tr; SPU_021741-tr; SPU_021741
SPU_022072-tr; SPU_022072-tr; SPU_022072
SPU_023698-tr; SPU_023698-tr; SPU_023698
SPU_024342-tr; SPU_024342-tr; SPU_024342
SPU_025880-tr; SPU_025880-tr; SPU_025880
SPU_026174-tr; SPU_026174-tr; SPU_026174
SPU_027036-tr; SPU_027036-tr; SPU_027036
SPU_027210-tr; SPU_027210-tr; SPU_027210
SPU_027412-tr; SPU_027412-tr; SPU_027412
SPU_027474-tr; SPU_027474-tr; SPU_027474
SPU_028399-tr; SPU_028399-tr; SPU_028399

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
373325
373341
373343
373346
752187
753158
753782
753944
754292
754479

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spu:373325
spu:373341
spu:373343
spu:373346
spu:753158
spu:753782
spu:753944
spu:754292
spu:754479

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03952 Genomic DNA Translation: CAA27581.1
V01355 Genomic DNA Translation: CAA24645.1
X06639 Genomic DNA Translation: CAA29847.1
X06641 Genomic DNA Translation: CAA29849.1
M32426 mRNA Translation: AAA30054.1
PIRiA02643 HSUR4P
S01618
RefSeqiNP_999707.1, NM_214542.1
NP_999713.1, NM_214548.1
NP_999715.1, NM_214550.1
NP_999716.1, NM_214551.1
XP_001175485.3, XM_001175485.3
XP_001177624.1, XM_001177624.2
XP_001178441.3, XM_001178441.3
XP_001178934.1, XM_001178934.3
XP_011661644.1, XM_011663342.1
XP_011663808.1, XM_011665506.1
XP_011678157.1, XM_011679855.1
XP_011679526.1, XM_011681224.1

3D structure databases

SMRiP62783
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7668.SPU_028399-tr

Proteomic databases

PRIDEiP62783

Genome annotation databases

EnsemblMetazoaiSPU_000685-tr; SPU_000685-tr; SPU_000685
SPU_000768-tr; SPU_000768-tr; SPU_000768
SPU_001725-tr; SPU_001725-tr; SPU_001725
SPU_002504-tr; SPU_002504-tr; SPU_002504
SPU_002699-tr; SPU_002699-tr; SPU_002699
SPU_002794-tr; SPU_002794-tr; SPU_002794
SPU_003064-tr; SPU_003064-tr; SPU_003064
SPU_003833-tr; SPU_003833-tr; SPU_003833
SPU_004941-tr; SPU_004941-tr; SPU_004941
SPU_005173-tr; SPU_005173-tr; SPU_005173
SPU_005210-tr; SPU_005210-tr; SPU_005210
SPU_005424-tr; SPU_005424-tr; SPU_005424
SPU_005591-tr; SPU_005591-tr; SPU_005591
SPU_005704-tr; SPU_005704-tr; SPU_005704
SPU_006061-tr; SPU_006061-tr; SPU_006061
SPU_007314-tr; SPU_007314-tr; SPU_007314
SPU_007489-tr; SPU_007489-tr; SPU_007489
SPU_007705-tr; SPU_007705-tr; SPU_007705
SPU_007762-tr; SPU_007762-tr; SPU_007762
SPU_007815-tr; SPU_007815-tr; SPU_007815
SPU_007953-tr; SPU_007953-tr; SPU_007953
SPU_008489-tr; SPU_008489-tr; SPU_008489
SPU_009329-tr; SPU_009329-tr; SPU_009329
SPU_009565-tr; SPU_009565-tr; SPU_009565
SPU_010745-tr; SPU_010745-tr; SPU_010745
SPU_011273-tr; SPU_011273-tr; SPU_011273
SPU_011384-tr; SPU_011384-tr; SPU_011384
SPU_011680-tr; SPU_011680-tr; SPU_011680
SPU_011907-tr; SPU_011907-tr; SPU_011907
SPU_012107-tr; SPU_012107-tr; SPU_012107
SPU_012231-tr; SPU_012231-tr; SPU_012231
SPU_012389-tr; SPU_012389-tr; SPU_012389
SPU_012802-tr; SPU_012802-tr; SPU_012802
SPU_014878-tr; SPU_014878-tr; SPU_014878
SPU_014893-tr; SPU_014893-tr; SPU_014893
SPU_014933-tr; SPU_014933-tr; SPU_014933
SPU_015166-tr; SPU_015166-tr; SPU_015166
SPU_015201-tr; SPU_015201-tr; SPU_015201
SPU_015645-tr; SPU_015645-tr; SPU_015645
SPU_015663-tr; SPU_015663-tr; SPU_015663
SPU_015694-tr; SPU_015694-tr; SPU_015694
SPU_015742-tr; SPU_015742-tr; SPU_015742
SPU_015911-tr; SPU_015911-tr; SPU_015911
SPU_015956-tr; SPU_015956-tr; SPU_015956
SPU_016469-tr; SPU_016469-tr; SPU_016469
SPU_017482-tr; SPU_017482-tr; SPU_017482
SPU_017997-tr; SPU_017997-tr; SPU_017997
SPU_019474-tr; SPU_019474-tr; SPU_019474
SPU_019847-tr; SPU_019847-tr; SPU_019847
SPU_020454-tr; SPU_020454-tr; SPU_020454
SPU_020503-tr; SPU_020503-tr; SPU_020503
SPU_020862-tr; SPU_020862-tr; SPU_020862
SPU_021741-tr; SPU_021741-tr; SPU_021741
SPU_022072-tr; SPU_022072-tr; SPU_022072
SPU_023698-tr; SPU_023698-tr; SPU_023698
SPU_024342-tr; SPU_024342-tr; SPU_024342
SPU_025880-tr; SPU_025880-tr; SPU_025880
SPU_026174-tr; SPU_026174-tr; SPU_026174
SPU_027036-tr; SPU_027036-tr; SPU_027036
SPU_027210-tr; SPU_027210-tr; SPU_027210
SPU_027412-tr; SPU_027412-tr; SPU_027412
SPU_027474-tr; SPU_027474-tr; SPU_027474
SPU_028399-tr; SPU_028399-tr; SPU_028399
GeneIDi373325
373341
373343
373346
752187
753158
753782
753944
754292
754479
KEGGispu:373325
spu:373341
spu:373343
spu:373346
spu:753158
spu:753782
spu:753944
spu:754292
spu:754479

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
373325

Phylogenomic databases

eggNOGiKOG3467 Eukaryota
COG2036 LUCA
HOGENOMiCLU_109117_2_3_1
InParanoidiP62783
KOiK11254
OMAiQKEHING
OrthoDBi1564596at2759

Family and domain databases

CDDicd00076 H4, 1 hit
Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR035425 CENP-T/H4_C
IPR009072 Histone-fold
IPR001951 Histone_H4
IPR019809 Histone_H4_CS
PfamiView protein in Pfam
PF15511 CENP-T_C, 1 hit
PRINTSiPR00623 HISTONEH4
SMARTiView protein in SMART
SM00417 H4, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
PROSITEiView protein in PROSITE
PS00047 HISTONE_H4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH4_STRPU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62783
Secondary accession number(s): P02306, P18678
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: January 23, 2007
Last modified: February 26, 2020
This is version 83 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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