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Protein

T4 Suppressor of prr

Gene

stp

Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Plays a role in the inactivation of several host DNA restriction systems including EcoprrI or EcoR124I. As a consequence, it activates the host anticodon nuclease PrrC. However, the phage-encoded RNA repair enzymes normally offset the damage.3 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHost-virus interaction, Restriction-modification system evasion by virus

Names & Taxonomyi

Protein namesi
Recommended name:
T4 Suppressor of prr
Short name:
Stp
Gene namesi
Name:stp
OrganismiEnterobacteria phage T4 (Bacteriophage T4)
Taxonomic identifieri10665 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000009087 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00001649851 – 26T4 Suppressor of prrAdd BLAST26

Family & Domainsi

Domaini

The conserved N-proximal 18 residue region of Stp is critical both for its anti-DNA restriction and ACNase activating functions.1 Publication

Family and domain databases

InterProiView protein in InterPro
IPR012585 Stp
PfamiView protein in Pfam
PF08133 Nuclease_act, 1 hit

Sequencei

Sequence statusi: Complete.

P62765-1 [UniParc]FASTAAdd to basket
« Hide
        10         20 
MSNFHNEHVM QFYRNNLKTK GVFGRQ
Length:26
Mass (Da):3,184
Last modified:August 16, 2004 - v1
Checksum:i50416719F5088D40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46884 Genomic DNA Translation: CAA86982.1
Z46874 Genomic DNA Translation: CAA86954.1
AF158101 Genomic DNA Translation: AAD42660.1
PIRiS55796 STBPT4
RefSeqiNP_049878.1, NC_000866.4

Genome annotation databases

GeneIDi1258673
KEGGivg:1258673

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46884 Genomic DNA Translation: CAA86982.1
Z46874 Genomic DNA Translation: CAA86954.1
AF158101 Genomic DNA Translation: AAD42660.1
PIRiS55796 STBPT4
RefSeqiNP_049878.1, NC_000866.4

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1258673
KEGGivg:1258673

Family and domain databases

InterProiView protein in InterPro
IPR012585 Stp
PfamiView protein in Pfam
PF08133 Nuclease_act, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSTP_BPT4
AccessioniPrimary (citable) accession number: P62765
Secondary accession number(s): P18788
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: May 10, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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