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Protein

40S ribosomal protein S4, X isoform

Gene

Rps4x

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • response to ethanol Source: RGD
  • translation Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-RNO-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-RNO-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-RNO-72649 Translation initiation complex formation
R-RNO-72689 Formation of a pool of free 40S subunits
R-RNO-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-RNO-72702 Ribosomal scanning and start codon recognition
R-RNO-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4, X isoform
Gene namesi
Name:Rps4x
Synonyms:Rps4
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi2324318 Rps4x

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001308101 – 26340S ribosomal protein S4, X isoformAdd BLAST263

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki230Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei233N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiP62703
PRIDEiP62703

PTM databases

iPTMnetiP62703
PhosphoSitePlusiP62703

Expressioni

Gene expression databases

BgeeiENSRNOG00000003201
ExpressionAtlasiP62703 baseline and differential
GenevisibleiP62703 RN

Interactioni

Subunit structurei

Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.By similarity

Protein-protein interaction databases

BioGridi1201774, 1 interactor
IntActiP62703, 3 interactors
STRINGi10116.ENSRNOP00000043988

Structurei

3D structure databases

ProteinModelPortaliP62703
SMRiP62703
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 104S4 RNA-bindingAdd BLAST63

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0378 Eukaryota
COG1471 LUCA
GeneTreeiENSGT00390000005569
HOGENOMiHOG000231325
HOVERGENiHBG000935
InParanoidiP62703
KOiK02987
OrthoDBiEOG091G0MYF
PhylomeDBiP62703
TreeFamiTF300612

Family and domain databases

CDDicd00165 S4, 1 hit
Gene3Di2.30.30.30, 1 hit
2.40.50.740, 1 hit
HAMAPiMF_00485 Ribosomal_S4e, 1 hit
InterProiView protein in InterPro
IPR032277 40S_S4_C
IPR005824 KOW
IPR014722 Rib_L2_dom2
IPR000876 Ribosomal_S4e
IPR013845 Ribosomal_S4e_central_region
IPR038237 Ribosomal_S4e_central_sf
IPR013843 Ribosomal_S4e_N
IPR018199 Ribosomal_S4e_N_CS
IPR002942 S4_RNA-bd
PANTHERiPTHR11581 PTHR11581, 1 hit
PfamiView protein in Pfam
PF16121 40S_S4_C, 1 hit
PF00467 KOW, 1 hit
PF00900 Ribosomal_S4e, 1 hit
PF08071 RS4NT, 1 hit
PF01479 S4, 1 hit
PIRSFiPIRSF002116 Ribosomal_S4, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002667 Ribosomal_S4e_central, 1 hit
SMARTiView protein in SMART
SM00363 S4, 1 hit
PROSITEiView protein in PROSITE
PS00528 RIBOSOMAL_S4E, 1 hit
PS50889 S4, 1 hit

Sequencei

Sequence statusi: Complete.

P62703-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN
60 70 80 90 100
RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIDKTGENFR
110 120 130 140 150
LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP
160 170 180 190 200
DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER
210 220 230 240 250
HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE
260
ERDKRLAAKQ SSG
Length:263
Mass (Da):29,598
Last modified:January 23, 2007 - v2
Checksum:i87200E545A8958B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14210 mRNA Translation: CAA32427.1
BC086560 mRNA Translation: AAH86560.1
PIRiS14080 R3RT4
RefSeqiNP_001007601.1, NM_001007600.2
UniGeneiRn.196072
Rn.40171

Genome annotation databases

EnsembliENSRNOT00000076978; ENSRNOP00000067969; ENSRNOG00000003201
GeneIDi100362640
KEGGirno:100362640
UCSCiRGD:3600 rat

Similar proteinsi

Entry informationi

Entry nameiRS4X_RAT
AccessioniPrimary (citable) accession number: P62703
Secondary accession number(s): P12631
, P12750, P27576, P55831, Q14727
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 115 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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