UniProtKB - P62663 (RS3_THET2)
Protein
30S ribosomal protein S3
Gene
rpsC
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Functioni
Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity).By similarity
GO - Molecular functioni
- mRNA binding Source: UniProtKB-UniRule
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 30S ribosomal protein S3 |
Gene namesi | Name:rpsC Synonyms:rps3 Ordered Locus Names:TT_C1322 |
Organismi | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) |
Taxonomic identifieri | 262724 [NCBI] |
Taxonomic lineagei | Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus › |
Proteomesi |
|
Pathology & Biotechi
Chemistry databases
DrugBanki | DB08185, 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000130222 | 2 – 239 | 30S ribosomal protein S3Add BLAST | 238 |
Interactioni
Subunit structurei
Part of the 30S ribosomal subunit.
Forms a tight complex with proteins S10 and S14 (By similarity).
By similarityProtein-protein interaction databases
STRINGi | 262724.TT_C1322 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P62663 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P62663 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 40 – 108 | KH type-2Add BLAST | 69 |
Sequence similaritiesi
Belongs to the universal ribosomal protein uS3 family.Curated
Phylogenomic databases
eggNOGi | COG0092, Bacteria |
HOGENOMi | CLU_058591_0_2_0 |
OMAi | KTNPIGN |
OrthoDBi | 1132353at2 |
Family and domain databases
Gene3Di | 3.30.1140.32, 1 hit 3.30.300.20, 1 hit |
HAMAPi | MF_01309_B, Ribosomal_S3_B, 1 hit |
InterProi | View protein in InterPro IPR004087, KH_dom IPR015946, KH_dom-like_a/b IPR004044, KH_dom_type_2 IPR009019, KH_sf_prok-type IPR005704, Ribosomal_S3_bac-typ IPR001351, Ribosomal_S3_C IPR036419, Ribosomal_S3_C_sf IPR018280, Ribosomal_S3_CS |
Pfami | View protein in Pfam PF07650, KH_2, 1 hit PF00189, Ribosomal_S3_C, 1 hit |
SMARTi | View protein in SMART SM00322, KH, 1 hit |
SUPFAMi | SSF54814, SSF54814, 1 hit SSF54821, SSF54821, 1 hit |
TIGRFAMsi | TIGR01009, rpsC_bact, 1 hit |
PROSITEi | View protein in PROSITE PS50823, KH_TYPE_2, 1 hit PS00548, RIBOSOMAL_S3, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P62663-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGNKIHPIGF RLGITRDWES RWYAGKKQYR HLLLEDQRIR GLLEKELYSA
60 70 80 90 100
GLARVDIERA ADNVAVTVHV AKPGVVIGRG GERIRVLREE LAKLTGKNVA
110 120 130 140 150
LNVQEVQNPN LSAPLVAQRV AEQIERRFAV RRAIKQAVQR VMESGAKGAK
160 170 180 190 200
VIVSGRIGGA EQARTEWAAQ GRVPLHTLRA NIDYGFALAR TTYGVLGVKA
210 220 230
YIFLGEVIGG QKPKARPELP KAEERPRRRR PAVRVKKEE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ409330 Genomic DNA Translation: CAC35062.1 AE017221 Genomic DNA Translation: AAS81664.1 |
RefSeqi | WP_008633418.1, NC_005835.1 |
Genome annotation databases
EnsemblBacteriai | AAS81664; AAS81664; TT_C1322 |
GeneIDi | 3168725 |
KEGGi | tth:TT_C1322 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ409330 Genomic DNA Translation: CAC35062.1 AE017221 Genomic DNA Translation: AAS81664.1 |
RefSeqi | WP_008633418.1, NC_005835.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4KVB | X-ray | 4.20 | C | 1-239 | [»] | |
4V4I | X-ray | 3.71 | d | 1-239 | [»] | |
4V4J | X-ray | 3.83 | d | 1-239 | [»] | |
4V63 | X-ray | 3.21 | AC/CC | 1-239 | [»] | |
4V67 | X-ray | 3.00 | AC/CC | 1-239 | [»] | |
4V7P | X-ray | 3.62 | AC/DC | 2-207 | [»] | |
4V83 | X-ray | 3.50 | AC/CC | 2-207 | [»] | |
4V84 | X-ray | 3.40 | AC/CC | 2-207 | [»] | |
4V9J | X-ray | 3.86 | AC/CC | 2-208 | [»] | |
4V9K | X-ray | 3.50 | AC/CC | 2-208 | [»] | |
4V9L | X-ray | 3.50 | AC/CC | 2-208 | [»] | |
4V9M | X-ray | 4.00 | AC/CC | 2-208 | [»] | |
4V9N | X-ray | 3.40 | AC/CC | 2-207 | [»] | |
4V9Q | X-ray | 3.40 | BC/DC | 2-207 | [»] | |
4W29 | X-ray | 3.80 | AC/CC | 2-208 | [»] | |
4XEJ | X-ray | 3.80 | AS03/BS03 | 2-207 | [»] | |
5J4D | X-ray | 3.10 | LA/QC | 1-239 | [»] | |
SMRi | P62663 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 262724.TT_C1322 |
Chemistry databases
DrugBanki | DB08185, 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE |
Genome annotation databases
EnsemblBacteriai | AAS81664; AAS81664; TT_C1322 |
GeneIDi | 3168725 |
KEGGi | tth:TT_C1322 |
Phylogenomic databases
eggNOGi | COG0092, Bacteria |
HOGENOMi | CLU_058591_0_2_0 |
OMAi | KTNPIGN |
OrthoDBi | 1132353at2 |
Miscellaneous databases
EvolutionaryTracei | P62663 |
Family and domain databases
Gene3Di | 3.30.1140.32, 1 hit 3.30.300.20, 1 hit |
HAMAPi | MF_01309_B, Ribosomal_S3_B, 1 hit |
InterProi | View protein in InterPro IPR004087, KH_dom IPR015946, KH_dom-like_a/b IPR004044, KH_dom_type_2 IPR009019, KH_sf_prok-type IPR005704, Ribosomal_S3_bac-typ IPR001351, Ribosomal_S3_C IPR036419, Ribosomal_S3_C_sf IPR018280, Ribosomal_S3_CS |
Pfami | View protein in Pfam PF07650, KH_2, 1 hit PF00189, Ribosomal_S3_C, 1 hit |
SMARTi | View protein in SMART SM00322, KH, 1 hit |
SUPFAMi | SSF54814, SSF54814, 1 hit SSF54821, SSF54821, 1 hit |
TIGRFAMsi | TIGR01009, rpsC_bact, 1 hit |
PROSITEi | View protein in PROSITE PS50823, KH_TYPE_2, 1 hit PS00548, RIBOSOMAL_S3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RS3_THET2 | |
Accessioni | P62663Primary (citable) accession number: P62663 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 19, 2004 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 111 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries