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Entry version 157 (18 Sep 2019)
Sequence version 1 (05 Jul 2004)
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Protein

Small nuclear ribonucleoprotein G

Gene

SNRPG

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it is involved in histone 3'-end processing (PubMed:12975319).11 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, RNA-binding
Biological processmRNA processing, mRNA splicing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

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Reactomei
R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs
R-HSA-191859 snRNP Assembly
R-HSA-72163 mRNA Splicing - Major Pathway
R-HSA-72165 mRNA Splicing - Minor Pathway
R-HSA-73856 RNA Polymerase II Transcription Termination
R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Small nuclear ribonucleoprotein G
Short name:
snRNP-G
Alternative name(s):
Sm protein G
Short name:
Sm-G
Short name:
SmG
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SNRPG
Synonyms:PBSCG
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:11163 SNRPG

Online Mendelian Inheritance in Man (OMIM)

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MIMi
603542 gene

neXtProt; the human protein knowledge platform

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neXtProti
NX_P62308

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus, Spliceosome

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6637

Open Targets

More...
OpenTargetsi
ENSG00000143977

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA36004

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

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BioMutai
SNRPG

Domain mapping of disease mutations (DMDM)

More...
DMDMi
59800216

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001255451 – 76Small nuclear ribonucleoprotein GAdd BLAST76

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
P62308

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P62308

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
P62308

MaxQB - The MaxQuant DataBase

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MaxQBi
P62308

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P62308

PeptideAtlas

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PeptideAtlasi
P62308

PRoteomics IDEntifications database

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PRIDEi
P62308

ProteomicsDB human proteome resource

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ProteomicsDBi
57388

Consortium for Top Down Proteomics

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TopDownProteomicsi
P62308

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
P62308

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
P62308

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P62308

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000143977 Expressed in 91 organ(s), highest expression level in female gonad

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P62308 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P62308 HS

Organism-specific databases

Human Protein Atlas

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HPAi
HPA064152
HPA067814

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:19325628, PubMed:21516107, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (PubMed:19325628, PubMed:21516107, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).

Component of the U1 snRNP (PubMed:19325628, PubMed:25555158). The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C (PubMed:19325628, PubMed:25555158).

Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8 (PubMed:26912367).

Component of the U7 snRNP complex, or U7 Sm protein core complex, that is composed of the U7 snRNA and at least LSM10, LSM11, SNRPB, SNRPD3, SNRPE, SNRPF and SNRPG; the complex does not contain SNRPD1 and SNRPD2 (PubMed:11574479, PubMed:12975319).

Component of the U11/U12 snRNPs that are part of the U12-type spliceosome (PubMed:15146077). Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly (PubMed:18984161).

Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP (PubMed:18984161, PubMed:23333303).

13 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
112521, 138 interactors

CORUM comprehensive resource of mammalian protein complexes

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CORUMi
P62308

Database of interacting proteins

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DIPi
DIP-34627N

Protein interaction database and analysis system

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IntActi
P62308, 33 interactors

Molecular INTeraction database

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MINTi
P62308

STRING: functional protein association networks

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STRINGi
9606.ENSP00000272348

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

176
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P62308

Database of comparative protein structure models

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ModBasei
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

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EvolutionaryTracei
P62308

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the snRNP Sm proteins family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1780 Eukaryota
ENOG41122Q1 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00510000046985

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P62308

KEGG Orthology (KO)

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KOi
K11099

Identification of Orthologs from Complete Genome Data

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OMAi
NANRMIV

Database of Orthologous Groups

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OrthoDBi
1593201at2759

TreeFam database of animal gene trees

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TreeFami
TF315099

Family and domain databases

Conserved Domains Database

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CDDi
cd01719 Sm_G, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR001163 LSM_dom_euk/arc
IPR010920 LSM_dom_sf
IPR034098 Sm_G

Pfam protein domain database

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Pfami
View protein in Pfam
PF01423 LSM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00651 Sm, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF50182 SSF50182, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P62308-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKAHPPELK KFMDKKLSLK LNGGRHVQGI LRGFDPFMNL VIDECVEMAT
60 70
SGQQNNIGMV VIRGNSIIML EALERV
Length:76
Mass (Da):8,496
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i623302BF6BE758FE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JVQ0C9JVQ0_HUMAN
Small nuclear ribonucleoprotein G
SNRPG
96Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H013F5H013_HUMAN
Small nuclear ribonucleoprotein G
SNRPG
68Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q49AN9Q49AN9_HUMAN
Small nuclear ribonucleoprotein G
SNRPG
64Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X85373 mRNA Translation: CAA59689.1
CR456918 mRNA Translation: CAG33199.1
AC079338 Genomic DNA Translation: AAX81996.1
CH471053 Genomic DNA Translation: EAW99817.1
CH471053 Genomic DNA Translation: EAW99818.1
BC000070 mRNA Translation: AAH00070.1
BC022432 mRNA Translation: AAH22432.1
BC066302 mRNA Translation: AAH66302.1
BC070166 mRNA Translation: AAH70166.1
BC071880 mRNA Translation: AAH71880.1
BC106055 mRNA Translation: AAI06056.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS1903.1

Protein sequence database of the Protein Information Resource

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PIRi
S55054

NCBI Reference Sequences

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RefSeqi
NP_003087.1, NM_003096.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENST00000272348; ENSP00000272348; ENSG00000143977

Database of genes from NCBI RefSeq genomes

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GeneIDi
6637

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:6637

UCSC genome browser

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UCSCi
uc002sgp.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X85373 mRNA Translation: CAA59689.1
CR456918 mRNA Translation: CAG33199.1
AC079338 Genomic DNA Translation: AAX81996.1
CH471053 Genomic DNA Translation: EAW99817.1
CH471053 Genomic DNA Translation: EAW99818.1
BC000070 mRNA Translation: AAH00070.1
BC022432 mRNA Translation: AAH22432.1
BC066302 mRNA Translation: AAH66302.1
BC070166 mRNA Translation: AAH70166.1
BC071880 mRNA Translation: AAH71880.1
BC106055 mRNA Translation: AAI06056.1
CCDSiCCDS1903.1
PIRiS55054
RefSeqiNP_003087.1, NM_003096.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3CW1X-ray5.493/4/5/G1-76[»]
3JCRelectron microscopy7.00U/u1-76[»]
3PGWX-ray4.40G/J1-76[»]
4F7UX-ray1.90G/J1-76[»]
4PJOX-ray3.30G/U/g/u1-76[»]
4V98X-ray3.10A4/AH/AP/AX/Af/An/Av/B4/BH/BP/BX/Bf/Bn/Bv/CH/CP/CX/Cf/Cn/Cv1-76[»]
4WZJX-ray3.60AG/AN/AU/BG/BN/BU/CG/CN/CU/DG/DN/DU1-76[»]
5MQFelectron microscopy5.90d/k1-76[»]
5O9Zelectron microscopy4.50V/d/k1-76[»]
5XJCelectron microscopy3.60g/n1-76[»]
5XJLX-ray2.50G1-76[»]
5XJQX-ray3.28G1-76[»]
5XJRX-ray3.12G1-76[»]
5XJTX-ray2.92G1-76[»]
5XJUX-ray2.58G1-76[»]
5YZGelectron microscopy4.10g/n1-76[»]
5Z56electron microscopy5.10g/n1-76[»]
5Z57electron microscopy6.50g/n1-76[»]
5Z58electron microscopy4.90g/n1-76[»]
6AH0electron microscopy5.70S/d/n1-76[»]
6AHDelectron microscopy3.80S/f/n1-76[»]
6FF7electron microscopy4.50d/k1-76[»]
6ICZelectron microscopy3.00g/n1-76[»]
6ID0electron microscopy2.90g/n1-76[»]
6ID1electron microscopy2.86g/n1-76[»]
6QDVelectron microscopy3.30g/r4-76[»]
6QW6electron microscopy2.924g/5g1-76[»]
6QX9electron microscopy3.281g/2g/4g/5g1-76[»]
SMRiP62308
ModBaseiSearch...

Protein-protein interaction databases

BioGridi112521, 138 interactors
CORUMiP62308
DIPiDIP-34627N
IntActiP62308, 33 interactors
MINTiP62308
STRINGi9606.ENSP00000272348

PTM databases

iPTMnetiP62308
PhosphoSitePlusiP62308
SwissPalmiP62308

Polymorphism and mutation databases

BioMutaiSNRPG
DMDMi59800216

Proteomic databases

EPDiP62308
jPOSTiP62308
MassIVEiP62308
MaxQBiP62308
PaxDbiP62308
PeptideAtlasiP62308
PRIDEiP62308
ProteomicsDBi57388
TopDownProteomicsiP62308

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6637
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000272348; ENSP00000272348; ENSG00000143977
GeneIDi6637
KEGGihsa:6637
UCSCiuc002sgp.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6637
DisGeNETi6637

GeneCards: human genes, protein and diseases

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GeneCardsi
SNRPG
HGNCiHGNC:11163 SNRPG
HPAiHPA064152
HPA067814
MIMi603542 gene
neXtProtiNX_P62308
OpenTargetsiENSG00000143977
PharmGKBiPA36004

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1780 Eukaryota
ENOG41122Q1 LUCA
GeneTreeiENSGT00510000046985
InParanoidiP62308
KOiK11099
OMAiNANRMIV
OrthoDBi1593201at2759
TreeFamiTF315099

Enzyme and pathway databases

ReactomeiR-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs
R-HSA-191859 snRNP Assembly
R-HSA-72163 mRNA Splicing - Major Pathway
R-HSA-72165 mRNA Splicing - Minor Pathway
R-HSA-73856 RNA Polymerase II Transcription Termination
R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SNRPG human
EvolutionaryTraceiP62308

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
SNRPG

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
6637

Pharos

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Pharosi
P62308

Protein Ontology

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PROi
PR:P62308

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000143977 Expressed in 91 organ(s), highest expression level in female gonad
ExpressionAtlasiP62308 baseline and differential
GenevisibleiP62308 HS

Family and domain databases

CDDicd01719 Sm_G, 1 hit
InterProiView protein in InterPro
IPR001163 LSM_dom_euk/arc
IPR010920 LSM_dom_sf
IPR034098 Sm_G
PfamiView protein in Pfam
PF01423 LSM, 1 hit
SMARTiView protein in SMART
SM00651 Sm, 1 hit
SUPFAMiSSF50182 SSF50182, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRUXG_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62308
Secondary accession number(s): D6W5G6, Q15357, Q6IB86
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 18, 2019
This is version 157 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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