Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Due to a server migration, the UniProt 'ID mapping', 'Peptide search' and 'community bibliography submission' tools will not be available on the 19th April 2021 during the morning (EST).

UniProtKB - P62277 (RS13_HUMAN)

Entry version 180 (07 Apr 2021)
Sequence version 2 (23 Jan 2007)
Previous versions | rss
Add a publicationFeedback
Protein

40S ribosomal protein S13

Gene

RPS13

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P62277

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902, Peptide chain elongation
R-HSA-1799339, SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823, Viral mRNA Translation
R-HSA-2408557, Selenocysteine synthesis
R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649, Translation initiation complex formation
R-HSA-72689, Formation of a pool of free 40S subunits
R-HSA-72695, Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702, Ribosomal scanning and start codon recognition
R-HSA-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764, Eukaryotic Translation Termination
R-HSA-9010553, Regulation of expression of SLITs and ROBOs
R-HSA-9633012, Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

SIGNOR Signaling Network Open Resource

More...SIGNORi		P62277

Protein family/group databases

MoonProt database of moonlighting proteins

More...MoonProti		P62277

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S13
Alternative name(s):
Small ribosomal subunit protein uS151 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPS13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:10386, RPS13

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		180476, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P62277

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000110700.6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		6207

Open Targets

More...OpenTargetsi		ENSG00000110700

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA34785

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P62277, Tbio

Chemistry databases

Drug and drug target database

More...DrugBanki		DB11638, Artenimol

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		RPS13

Domain mapping of disease mutations (DMDM)

More...DMDMi		50403608

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001156612 – 15140S ribosomal protein S13Add BLAST150

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei27N6-acetyllysine; alternateCombined sources1
Modified residuei27N6-succinyllysine; alternateBy similarity1
Modified residuei30PhosphoserineCombined sources1
Modified residuei34N6-succinyllysineBy similarity1
Modified residuei38PhosphotyrosineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki43Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P62277

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P62277

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P62277

MaxQB - The MaxQuant DataBase

More...MaxQBi		P62277

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P62277

PeptideAtlas

More...PeptideAtlasi		P62277

PRoteomics IDEntifications database

More...PRIDEi		P62277

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		57384

Consortium for Top Down Proteomics

More...TopDownProteomicsi		P62277

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P62277

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P62277

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P62277

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000110700, Expressed in cortical plate and 120 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P62277, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P62277, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000110700, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		112121, 327 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-5223, 40S cytosolic small ribosomal subunit

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P62277

Protein interaction database and analysis system

More...IntActi		P62277, 85 interactors

Molecular INTeraction database

More...MINTi		P62277

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000435777

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P62277, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1151
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P62277

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS15 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0400, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000017491

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_090139_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P62277

Identification of Orthologs from Complete Genome Data

More...OMAi		WHLVKKA

Database of Orthologous Groups

More...OrthoDBi		1387147at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P62277

TreeFam database of animal gene trees

More...TreeFami		TF300190

Family and domain databases

Conserved Domains Database

More...CDDi		cd00353, Ribosomal_S15p_S13e, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_01343_A, Ribosomal_S15_A, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012606, Ribosomal_S13/S15_N
IPR000589, Ribosomal_S15
IPR023029, Ribosomal_S15P
IPR009068, S15_NS1_RNA-bd

The PANTHER Classification System

More...PANTHERi		PTHR11885, PTHR11885, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08069, Ribosomal_S13_N, 1 hit
PF00312, Ribosomal_S15, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01386, Ribosomal_S13_N, 1 hit
SM01387, Ribosomal_S15, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47060, SSF47060, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00362, RIBOSOMAL_S15, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P62277-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRMHAPGKG LSQSALPYRR SVPTWLKLTS DDVKEQIYKL AKKGLTPSQI 
        60         70         80         90        100
GVILRDSHGV AQVRFVTGNK ILRILKSKGL APDLPEDLYH LIKKAVAVRK 
       110        120        130        140        150
HLERNRKDKD AKFRLILIES RIHRLARYYK TKRVLPPNWK YESSTASALV 

A
Length:151
Mass (Da):17,222
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i23F94D38F87B8D53
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KMX5J3KMX5_HUMAN
40S ribosomal protein S13
RPS13
148Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PS50E9PS50_HUMAN
40S ribosomal protein S13
RPS13
116Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti82P → S in AAC15854 (Ref. 8) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
L01124 mRNA Translation: AAA60283.1
X79239 mRNA Translation: CAA55821.1
D88010 Genomic DNA Translation: BAA13528.1
AK312060 mRNA Translation: BAG34996.1
CH471064 Genomic DNA Translation: EAW68448.1
BC000475 mRNA Translation: AAH00475.1
BC006772 mRNA Translation: AAH06772.1
BC029732 mRNA Translation: AAH29732.1
BC066322 mRNA Translation: AAH66322.1
BC100032 mRNA Translation: AAI00033.1
L05090 mRNA Translation: AAC15854.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS7823.1

Protein sequence database of the Protein Information Resource

More...PIRi		S34109

NCBI Reference Sequences

More...RefSeqi		NP_001008.1, NM_001017.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000525634; ENSP00000435777; ENSG00000110700

Database of genes from NCBI RefSeq genomes

More...GeneIDi		6207

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:6207

UCSC genome browser

More...UCSCi		uc001mmp.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L01124 mRNA Translation: AAA60283.1
X79239 mRNA Translation: CAA55821.1
D88010 Genomic DNA Translation: BAA13528.1
AK312060 mRNA Translation: BAG34996.1
CH471064 Genomic DNA Translation: EAW68448.1
BC000475 mRNA Translation: AAH00475.1
BC006772 mRNA Translation: AAH06772.1
BC029732 mRNA Translation: AAH29732.1
BC066322 mRNA Translation: AAH66322.1
BC100032 mRNA Translation: AAI00033.1
L05090 mRNA Translation: AAC15854.1
CCDSiCCDS7823.1
PIRiS34109
RefSeqiNP_001008.1, NM_001017.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-SN1-151[»]
4V6Xelectron microscopy5.00AN1-151[»]
5A2Qelectron microscopy3.90N1-151[»]
5AJ0electron microscopy3.50BN1-151[»]
5FLXelectron microscopy3.90N1-151[»]
5LKSelectron microscopy3.60SN1-151[»]
5OA3electron microscopy4.30N1-151[»]
5T2Celectron microscopy3.60AN1-151[»]
5VYCX-ray6.00N1/N2/N3/N4/N5/N61-151[»]
6EK0electron microscopy2.90SN1-151[»]
6FECelectron microscopy6.30Z2-151[»]
6G18electron microscopy3.60N1-151[»]
6G4Selectron microscopy4.00N1-151[»]
6G4Welectron microscopy4.50N1-151[»]
6G51electron microscopy4.10N1-151[»]
6G53electron microscopy4.50N1-151[»]
6G5Helectron microscopy3.60N1-151[»]
6G5Ielectron microscopy3.50N1-151[»]
6IP5electron microscopy3.903K1-151[»]
6IP6electron microscopy4.503K1-151[»]
6IP8electron microscopy3.903K1-151[»]
6OLEelectron microscopy3.10SN2-151[»]
6OLFelectron microscopy3.90SN2-151[»]
6OLGelectron microscopy3.40BN2-150[»]
6OLIelectron microscopy3.50SN2-151[»]
6OLZelectron microscopy3.90BN2-150[»]
6OM0electron microscopy3.10SN2-151[»]
6OM7electron microscopy3.70SN2-151[»]
6QZPelectron microscopy2.90SN2-151[»]
6XA1electron microscopy2.80SN2-151[»]
6Y0Gelectron microscopy3.20SN1-151[»]
6Y2Lelectron microscopy3.00SN1-151[»]
6Y57electron microscopy3.50SN1-151[»]
6YBDelectron microscopy3.30I1-151[»]
6YBWelectron microscopy3.10I1-151[»]
6Z6Lelectron microscopy3.00SN1-151[»]
6Z6Melectron microscopy3.10SN1-151[»]
6Z6Nelectron microscopy2.90SN1-151[»]
6ZLWelectron microscopy2.60N1-151[»]
6ZM7electron microscopy2.70SN1-151[»]
6ZMEelectron microscopy3.00SN1-151[»]
6ZMIelectron microscopy2.60SN1-151[»]
6ZMOelectron microscopy3.10SN1-151[»]
6ZMTelectron microscopy3.00N1-151[»]
6ZMWelectron microscopy3.70I1-151[»]
6ZN5electron microscopy3.20N2-150[»]
6ZOJelectron microscopy2.80N1-151[»]
6ZOKelectron microscopy2.80N1-151[»]
6ZONelectron microscopy3.00m1-151[»]
6ZP4electron microscopy2.90m1-151[»]
6ZVHelectron microscopy2.90N2-151[»]
6ZVJelectron microscopy3.80m2-150[»]
6ZXDelectron microscopy3.20N1-151[»]
6ZXEelectron microscopy3.00N1-151[»]
6ZXFelectron microscopy3.70N1-151[»]
6ZXGelectron microscopy2.60N1-151[»]
6ZXHelectron microscopy2.70N1-151[»]
7A09electron microscopy3.50m1-151[»]
7K5Ielectron microscopy2.90N1-151[»]
SMRiP62277
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi112121, 327 interactors
ComplexPortaliCPX-5223, 40S cytosolic small ribosomal subunit
CORUMiP62277
IntActiP62277, 85 interactors
MINTiP62277
STRINGi9606.ENSP00000435777

Chemistry databases

DrugBankiDB11638, Artenimol

Protein family/group databases

MoonProtiP62277

PTM databases

iPTMnetiP62277
PhosphoSitePlusiP62277
SwissPalmiP62277

Genetic variation databases

BioMutaiRPS13
DMDMi50403608

Proteomic databases

EPDiP62277
jPOSTiP62277
MassIVEiP62277
MaxQBiP62277
PaxDbiP62277
PeptideAtlasiP62277
PRIDEiP62277
ProteomicsDBi57384
TopDownProteomicsiP62277

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		42458, 226 antibodies

The DNASU plasmid repository

More...DNASUi		6207

Genome annotation databases

EnsembliENST00000525634; ENSP00000435777; ENSG00000110700
GeneIDi6207
KEGGihsa:6207
UCSCiuc001mmp.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		6207
DisGeNETi6207

GeneCards: human genes, protein and diseases

More...GeneCardsi		RPS13
HGNCiHGNC:10386, RPS13
HPAiENSG00000110700, Low tissue specificity
MIMi180476, gene
neXtProtiNX_P62277
OpenTargetsiENSG00000110700
PharmGKBiPA34785
VEuPathDBiHostDB:ENSG00000110700.6

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0400, Eukaryota
GeneTreeiENSGT00390000017491
HOGENOMiCLU_090139_1_0_1
InParanoidiP62277
OMAiWHLVKKA
OrthoDBi1387147at2759
PhylomeDBiP62277
TreeFamiTF300190

Enzyme and pathway databases

PathwayCommonsiP62277
ReactomeiR-HSA-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902, Peptide chain elongation
R-HSA-1799339, SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823, Viral mRNA Translation
R-HSA-2408557, Selenocysteine synthesis
R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649, Translation initiation complex formation
R-HSA-72689, Formation of a pool of free 40S subunits
R-HSA-72695, Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702, Ribosomal scanning and start codon recognition
R-HSA-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764, Eukaryotic Translation Termination
R-HSA-9010553, Regulation of expression of SLITs and ROBOs
R-HSA-9633012, Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SIGNORiP62277

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		6207, 786 hits in 965 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		RPS13, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		RPS13

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		6207
PharosiP62277, Tbio

Protein Ontology

More...PROi		PR:P62277
RNActiP62277, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000110700, Expressed in cortical plate and 120 other tissues
ExpressionAtlasiP62277, baseline and differential
GenevisibleiP62277, HS

Family and domain databases

CDDicd00353, Ribosomal_S15p_S13e, 1 hit
HAMAPiMF_01343_A, Ribosomal_S15_A, 1 hit
InterProiView protein in InterPro
IPR012606, Ribosomal_S13/S15_N
IPR000589, Ribosomal_S15
IPR023029, Ribosomal_S15P
IPR009068, S15_NS1_RNA-bd
PANTHERiPTHR11885, PTHR11885, 1 hit
PfamiView protein in Pfam
PF08069, Ribosomal_S13_N, 1 hit
PF00312, Ribosomal_S15, 1 hit
SMARTiView protein in SMART
SM01386, Ribosomal_S13_N, 1 hit
SM01387, Ribosomal_S15, 1 hit
SUPFAMiSSF47060, SSF47060, 1 hit
PROSITEiView protein in PROSITE
PS00362, RIBOSOMAL_S15, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS13_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62277
Secondary accession number(s): B2R549
, P19116, Q02546, Q29200, Q498Y0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: January 23, 2007
Last modified: April 7, 2021
This is version 180 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again