UniProtKB - P62258 (1433E_HUMAN)
14-3-3 protein epsilon
YWHAE
Functioni
GO - Molecular functioni
- cadherin binding Source: BHF-UCL
- calcium channel regulator activity Source: SynGO-UCL
- enzyme binding Source: UniProtKB
- histone deacetylase binding Source: BHF-UCL
- identical protein binding Source: IntAct
- ion channel binding Source: BHF-UCL
- MHC class II protein complex binding Source: UniProtKB
- phosphoprotein binding Source: BHF-UCL
- phosphoserine residue binding Source: BHF-UCL
- potassium channel regulator activity Source: BHF-UCL
- protein heterodimerization activity Source: BHF-UCL
- RNA binding Source: UniProtKB
- scaffold protein binding Source: UniProtKB
- ubiquitin protein ligase binding Source: ParkinsonsUK-UCL
GO - Biological processi
- cellular response to heat Source: UniProtKB
- ciliary basal body-plasma membrane docking Source: Reactome
- G2/M transition of mitotic cell cycle Source: Reactome
- hippo signaling Source: Reactome
- intracellular signal transduction Source: ProtInc
- MAPK cascade Source: UniProtKB
- membrane repolarization during cardiac muscle cell action potential Source: BHF-UCL
- negative regulation of calcium ion export across plasma membrane Source: SynGO-UCL
- negative regulation of calcium ion transmembrane transporter activity Source: SynGO-UCL
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Reactome
- negative regulation of peptidyl-serine dephosphorylation Source: BHF-UCL
- positive regulation of protein export from nucleus Source: UniProtKB
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Source: Reactome
- protein localization to nucleus Source: UniProtKB
- regulation of cellular response to heat Source: Reactome
- regulation of cytosolic calcium ion concentration Source: SynGO-UCL
- regulation of G2/M transition of mitotic cell cycle Source: Reactome
- regulation of heart rate by cardiac conduction Source: BHF-UCL
- regulation of heart rate by hormone Source: BHF-UCL
- regulation of membrane repolarization Source: BHF-UCL
- regulation of postsynaptic membrane neurotransmitter receptor levels Source: Ensembl
- regulation of potassium ion transmembrane transporter activity Source: BHF-UCL
- substantia nigra development Source: UniProtKB
- viral process Source: UniProtKB-KW
Keywordsi
Biological process | Host-virus interaction |
Enzyme and pathway databases
PathwayCommonsi | P62258 |
Reactomei | R-HSA-111447, Activation of BAD and translocation to mitochondria R-HSA-1445148, Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-2028269, Signaling by Hippo R-HSA-205025, NADE modulates death signalling R-HSA-2565942, Regulation of PLK1 Activity at G2/M Transition R-HSA-3371453, Regulation of HSF1-mediated heat shock response R-HSA-3371511, HSF1 activation R-HSA-380259, Loss of Nlp from mitotic centrosomes R-HSA-380270, Recruitment of mitotic centrosome proteins and complexes R-HSA-380284, Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380320, Recruitment of NuMA to mitotic centrosomes R-HSA-5620912, Anchoring of the basal body to the plasma membrane R-HSA-5625740, RHO GTPases activate PKNs R-HSA-5628897, TP53 Regulates Metabolic Genes R-HSA-75035, Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-8854518, AURKA Activation by TPX2 R-HSA-8862803, Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8876198, RAB GEFs exchange GTP for GDP on RABs |
SignaLinki | P62258 |
SIGNORi | P62258 |
Protein family/group databases
MoonDBi | P62258, Predicted |
Names & Taxonomyi
Protein namesi | Recommended name: 14-3-3 protein epsilonShort name: 14-3-3E |
Gene namesi | Name:YWHAE |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:12851, YWHAE |
MIMi | 605066, gene |
neXtProti | NX_P62258 |
VEuPathDBi | HostDB:ENSG00000108953.16 |
Subcellular locationi
Nucleus
- Nucleus 1 Publication
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Other locations
- Melanosome 2 Publications
Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.2 Publications
Cytoskeleton
- kinesin complex Source: Ensembl
Cytosol
- cytosol Source: HPA
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
Mitochondrion
- mitochondrion Source: GOC
Nucleus
- nucleus Source: UniProtKB
Other locations
- central region of growth cone Source: Ensembl
- cytoplasm Source: UniProtKB
- focal adhesion Source: UniProtKB
- glutamatergic synapse Source: Ensembl
- melanosome Source: UniProtKB-SubCell
- membrane Source: UniProtKB
Keywords - Cellular componenti
Cytoplasm, NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 7531 |
MalaCardsi | YWHAE |
OpenTargetsi | ENSG00000108953 |
Orphaneti | 217385, 17p13.3 microduplication syndrome 457246, Clear cell sarcoma of kidney 261257, Distal 17p13.3 microdeletion syndrome 213711, Endometrial stromal sarcoma 531, Miller-Dieker syndrome |
PharmGKBi | PA37440 |
Miscellaneous databases
Pharosi | P62258, Tbio |
Chemistry databases
ChEMBLi | CHEMBL3329082 |
DrugBanki | DB01780, Fusicoccin DB12695, Phenethyl Isothiocyanate |
Genetic variation databases
BioMutai | YWHAE |
DMDMi | 51702210 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000058618 | 1 – 255 | 14-3-3 protein epsilonAdd BLAST | 255 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineCombined sources1 Publication | 1 | |
Modified residuei | 50 | N6-acetyllysine; alternateCombined sources | 1 | |
Cross-linki | 50 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources | ||
Modified residuei | 65 | PhosphoserineBy similarity | 1 | |
Modified residuei | 69 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 118 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 123 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 131 | PhosphotyrosineBy similarity | 1 | |
Modified residuei | 137 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 210 | PhosphoserineCombined sources | 1 | |
Modified residuei | 232 | PhosphothreonineCombined sources | 1 |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | P62258 |
jPOSTi | P62258 |
MassIVEi | P62258 |
PaxDbi | P62258 |
PeptideAtlasi | P62258 |
PRIDEi | P62258 |
ProteomicsDBi | 57377 57378 [P62258-2] |
TopDownProteomicsi | P62258-1 [P62258-1] |
2D gel databases
OGPi | P42655 |
UCD-2DPAGEi | P62258 |
PTM databases
iPTMneti | P62258 |
MetOSitei | P62258 |
PhosphoSitePlusi | P62258 |
SwissPalmi | P62258 |
Expressioni
Gene expression databases
Bgeei | ENSG00000108953, Expressed in female gonad and 251 other tissues |
ExpressionAtlasi | P62258, baseline and differential |
Genevisiblei | P62258, HS |
Organism-specific databases
HPAi | ENSG00000108953, Low tissue specificity |
Interactioni
Subunit structurei
Homodimer (PubMed:17085597). Heterodimerizes with YWHAZ (PubMed:16376338).
Interacts with PKA-phosphorylated AANAT (PubMed:11427721).
Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm (PubMed:15696159).
Interacts with ARHGEF28 (By similarity).
Interacts with BEX3 (By similarity). Weakly interacts with CDKN1B (PubMed:12042314).
Interacts with the 'Thr-369' phosphorylated form of DAPK2 (PubMed:26047703).
Interacts with DENND1A (PubMed:26055712).
Interacts with GAB2 (PubMed:19172738).
Interacts with phosphorylated GRB10 (PubMed:15722337).
Interacts with KSR1 (PubMed:10409742).
Interacts with NDEL1 (By similarity).
Interacts with PI4KB, TBC1D22A and TBC1D22B (PubMed:23572552).
Interacts with the phosphorylated (by AKT1) form of SRPK2 (PubMed:19592491).
Interacts with TIAM2.
Interacts with the 'Ser-1134' and 'Ser-1161' phosphorylated form of SOS1 (By similarity).
Interacts with ZFP36 (via phosphorylated form) (By similarity).
Interacts with SLITRK1 (PubMed:19640509).
Interacts with HSF1 (via phosphorylated form); this interaction promotes HSF1 sequestration in the cytoplasm in a ERK-dependent manner (PubMed:12917326).
Interacts with RIPOR2 isoform 2 (PubMed:25588844).
Interacts with KLHL22; required for the nuclear localization of KLHL22 upon amino acid starvation (PubMed:29769719).
Interacts with CRTC1 (PubMed:30611118).
Interacts with CRTC2 (probably when phosphorylated at 'Ser-171') (PubMed:30611118).
Interacts with CRTC3 (probably when phosphorylated at 'Ser-162' and/or 'Ser-273') (PubMed:30611118).
Interacts with ATP2B1; this interaction inhibits calcium-transporting ATPase activity (PubMed:18029012).
By similarity18 Publications(Microbial infection) Interacts with HCV core protein.
1 PublicationSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 57 | Interaction with phosphoserine on interacting protein | 1 | |
Sitei | 130 | Interaction with phosphoserine on interacting protein | 1 |
Binary interactionsi
Hide detailsP62258
GO - Molecular functioni
- cadherin binding Source: BHF-UCL
- enzyme binding Source: UniProtKB
- histone deacetylase binding Source: BHF-UCL
- identical protein binding Source: IntAct
- ion channel binding Source: BHF-UCL
- phosphoprotein binding Source: BHF-UCL
- phosphoserine residue binding Source: BHF-UCL
- protein heterodimerization activity Source: BHF-UCL
- scaffold protein binding Source: UniProtKB
- ubiquitin protein ligase binding Source: ParkinsonsUK-UCL
Protein-protein interaction databases
BioGRIDi | 113363, 597 interactors |
CORUMi | P62258 |
DIPi | DIP-36676N |
ELMi | P62258 |
IntActi | P62258, 271 interactors |
MINTi | P62258 |
STRINGi | 9606.ENSP00000264335 |
Miscellaneous databases
RNActi | P62258, protein |
Structurei
Secondary structure
3D structure databases
SMRi | P62258 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P62258 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0841, Eukaryota |
GeneTreei | ENSGT01010000222256 |
HOGENOMi | CLU_058290_0_0_1 |
InParanoidi | P62258 |
OMAi | YKNATEV |
PhylomeDBi | P62258 |
TreeFami | TF102003 |
Family and domain databases
Gene3Di | 1.20.190.20, 1 hit |
IDEALi | IID00512 |
InterProi | View protein in InterPro IPR000308, 14-3-3 IPR023409, 14-3-3_CS IPR036815, 14-3-3_dom_sf IPR023410, 14-3-3_domain |
PANTHERi | PTHR18860, PTHR18860, 1 hit |
Pfami | View protein in Pfam PF00244, 14-3-3, 1 hit |
PIRSFi | PIRSF000868, 14-3-3, 1 hit |
PRINTSi | PR00305, 1433ZETA |
SMARTi | View protein in SMART SM00101, 14_3_3, 1 hit |
SUPFAMi | SSF48445, SSF48445, 1 hit |
PROSITEi | View protein in PROSITE PS00796, 1433_1, 1 hit PS00797, 1433_2, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MDDREDLVYQ AKLAEQAERY DEMVESMKKV AGMDVELTVE ERNLLSVAYK
60 70 80 90 100
NVIGARRASW RIISSIEQKE ENKGGEDKLK MIREYRQMVE TELKLICCDI
110 120 130 140 150
LDVLDKHLIP AANTGESKVF YYKMKGDYHR YLAEFATGND RKEAAENSLV
160 170 180 190 200
AYKAASDIAM TELPPTHPIR LGLALNFSVF YYEILNSPDR ACRLAKAAFD
210 220 230 240 250
DAIAELDTLS EESYKDSTLI MQLLRDNLTL WTSDMQGDGE EQNKEALQDV
EDENQ
The sequence of this isoform differs from the canonical sequence as follows:
1-22: Missing.
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketI3L3T1 | I3L3T1_HUMAN | 14-3-3 protein epsilon | YWHAE | 107 | Annotation score: | ||
B4DJF2 | B4DJF2_HUMAN | 14-3-3 protein epsilon | YWHAE | 94 | Annotation score: | ||
K7EIT4 | K7EIT4_HUMAN | 14-3-3 protein epsilon | YWHAE | 109 | Annotation score: | ||
K7EM20 | K7EM20_HUMAN | 14-3-3 protein epsilon | YWHAE | 115 | Annotation score: | ||
I3L0W5 | I3L0W5_HUMAN | 14-3-3 protein epsilon | YWHAE | 38 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 106 – 107 | KH → NY AA sequence (PubMed:2026444).Curated | 2 | |
Sequence conflicti | 143 | E → F AA sequence (PubMed:2026444).Curated | 1 | |
Sequence conflicti | 148 | S → T AA sequence (PubMed:2026444).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_040621 | 1 – 22 | Missing in isoform SV. 2 PublicationsAdd BLAST | 22 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U20972 mRNA Translation: AAC50175.1 U54778 mRNA Translation: AAC50710.1 U43399 mRNA Translation: AAC50625.1 U43430 mRNA Translation: AAD00026.1 U28936 mRNA Translation: AAA75301.1 AB017103 Genomic DNA Translation: BAA32538.1 AY883089 mRNA Translation: AAX68683.1 AK128785 mRNA Translation: BAG54733.1 AK295260 mRNA Translation: BAG58249.1 AK316185 mRNA Translation: BAH14556.1 BT007161 mRNA Translation: AAP35825.1 CH471108 Genomic DNA Translation: EAW90628.1 CH471108 Genomic DNA Translation: EAW90629.1 BC000179 mRNA Translation: AAH00179.1 BC001440 mRNA Translation: AAH01440.1 |
CCDSi | CCDS11001.1 [P62258-1] |
PIRi | A61235 I38947 |
RefSeqi | NP_006752.1, NM_006761.4 [P62258-1] |
Genome annotation databases
Ensembli | ENST00000264335; ENSP00000264335; ENSG00000108953 [P62258-1] ENST00000571732; ENSP00000461762; ENSG00000108953 [P62258-2] ENST00000616643; ENSP00000481059; ENSG00000274474 [P62258-2] ENST00000627231; ENSP00000487356; ENSG00000274474 [P62258-1] |
GeneIDi | 7531 |
KEGGi | hsa:7531 |
UCSCi | uc002fsk.4, human [P62258-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U20972 mRNA Translation: AAC50175.1 U54778 mRNA Translation: AAC50710.1 U43399 mRNA Translation: AAC50625.1 U43430 mRNA Translation: AAD00026.1 U28936 mRNA Translation: AAA75301.1 AB017103 Genomic DNA Translation: BAA32538.1 AY883089 mRNA Translation: AAX68683.1 AK128785 mRNA Translation: BAG54733.1 AK295260 mRNA Translation: BAG58249.1 AK316185 mRNA Translation: BAH14556.1 BT007161 mRNA Translation: AAP35825.1 CH471108 Genomic DNA Translation: EAW90628.1 CH471108 Genomic DNA Translation: EAW90629.1 BC000179 mRNA Translation: AAH00179.1 BC001440 mRNA Translation: AAH01440.1 |
CCDSi | CCDS11001.1 [P62258-1] |
PIRi | A61235 I38947 |
RefSeqi | NP_006752.1, NM_006761.4 [P62258-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2BR9 | X-ray | 1.75 | A | 1-233 | [»] | |
3UAL | X-ray | 1.80 | A | 1-232 | [»] | |
3UBW | X-ray | 1.90 | A | 1-234 | [»] | |
6EIH | X-ray | 2.70 | A | 3-232 | [»] | |
SMRi | P62258 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 113363, 597 interactors |
CORUMi | P62258 |
DIPi | DIP-36676N |
ELMi | P62258 |
IntActi | P62258, 271 interactors |
MINTi | P62258 |
STRINGi | 9606.ENSP00000264335 |
Chemistry databases
ChEMBLi | CHEMBL3329082 |
DrugBanki | DB01780, Fusicoccin DB12695, Phenethyl Isothiocyanate |
Protein family/group databases
MoonDBi | P62258, Predicted |
PTM databases
iPTMneti | P62258 |
MetOSitei | P62258 |
PhosphoSitePlusi | P62258 |
SwissPalmi | P62258 |
Genetic variation databases
BioMutai | YWHAE |
DMDMi | 51702210 |
2D gel databases
OGPi | P42655 |
UCD-2DPAGEi | P62258 |
Proteomic databases
EPDi | P62258 |
jPOSTi | P62258 |
MassIVEi | P62258 |
PaxDbi | P62258 |
PeptideAtlasi | P62258 |
PRIDEi | P62258 |
ProteomicsDBi | 57377 57378 [P62258-2] |
TopDownProteomicsi | P62258-1 [P62258-1] |
Protocols and materials databases
Antibodypediai | 1898, 480 antibodies |
CPTCi | P62258, 3 antibodies |
DNASUi | 7531 |
Genome annotation databases
Ensembli | ENST00000264335; ENSP00000264335; ENSG00000108953 [P62258-1] ENST00000571732; ENSP00000461762; ENSG00000108953 [P62258-2] ENST00000616643; ENSP00000481059; ENSG00000274474 [P62258-2] ENST00000627231; ENSP00000487356; ENSG00000274474 [P62258-1] |
GeneIDi | 7531 |
KEGGi | hsa:7531 |
UCSCi | uc002fsk.4, human [P62258-1] |
Organism-specific databases
CTDi | 7531 |
DisGeNETi | 7531 |
GeneCardsi | YWHAE |
HGNCi | HGNC:12851, YWHAE |
HPAi | ENSG00000108953, Low tissue specificity |
MalaCardsi | YWHAE |
MIMi | 605066, gene |
neXtProti | NX_P62258 |
OpenTargetsi | ENSG00000108953 |
Orphaneti | 217385, 17p13.3 microduplication syndrome 457246, Clear cell sarcoma of kidney 261257, Distal 17p13.3 microdeletion syndrome 213711, Endometrial stromal sarcoma 531, Miller-Dieker syndrome |
PharmGKBi | PA37440 |
VEuPathDBi | HostDB:ENSG00000108953.16 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0841, Eukaryota |
GeneTreei | ENSGT01010000222256 |
HOGENOMi | CLU_058290_0_0_1 |
InParanoidi | P62258 |
OMAi | YKNATEV |
PhylomeDBi | P62258 |
TreeFami | TF102003 |
Enzyme and pathway databases
PathwayCommonsi | P62258 |
Reactomei | R-HSA-111447, Activation of BAD and translocation to mitochondria R-HSA-1445148, Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-2028269, Signaling by Hippo R-HSA-205025, NADE modulates death signalling R-HSA-2565942, Regulation of PLK1 Activity at G2/M Transition R-HSA-3371453, Regulation of HSF1-mediated heat shock response R-HSA-3371511, HSF1 activation R-HSA-380259, Loss of Nlp from mitotic centrosomes R-HSA-380270, Recruitment of mitotic centrosome proteins and complexes R-HSA-380284, Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380320, Recruitment of NuMA to mitotic centrosomes R-HSA-5620912, Anchoring of the basal body to the plasma membrane R-HSA-5625740, RHO GTPases activate PKNs R-HSA-5628897, TP53 Regulates Metabolic Genes R-HSA-75035, Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-8854518, AURKA Activation by TPX2 R-HSA-8862803, Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8876198, RAB GEFs exchange GTP for GDP on RABs |
SignaLinki | P62258 |
SIGNORi | P62258 |
Miscellaneous databases
BioGRID-ORCSi | 7531, 193 hits in 965 CRISPR screens |
ChiTaRSi | YWHAE, human |
EvolutionaryTracei | P62258 |
GeneWikii | YWHAE |
GenomeRNAii | 7531 |
Pharosi | P62258, Tbio |
PROi | PR:P62258 |
RNActi | P62258, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000108953, Expressed in female gonad and 251 other tissues |
ExpressionAtlasi | P62258, baseline and differential |
Genevisiblei | P62258, HS |
Family and domain databases
Gene3Di | 1.20.190.20, 1 hit |
IDEALi | IID00512 |
InterProi | View protein in InterPro IPR000308, 14-3-3 IPR023409, 14-3-3_CS IPR036815, 14-3-3_dom_sf IPR023410, 14-3-3_domain |
PANTHERi | PTHR18860, PTHR18860, 1 hit |
Pfami | View protein in Pfam PF00244, 14-3-3, 1 hit |
PIRSFi | PIRSF000868, 14-3-3, 1 hit |
PRINTSi | PR00305, 1433ZETA |
SMARTi | View protein in SMART SM00101, 14_3_3, 1 hit |
SUPFAMi | SSF48445, SSF48445, 1 hit |
PROSITEi | View protein in PROSITE PS00796, 1433_1, 1 hit PS00797, 1433_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | 1433E_HUMAN | |
Accessioni | P62258Primary (citable) accession number: P62258 Secondary accession number(s): B3KY71 Q7M4R4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 192 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families