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Protein

40S ribosomal protein S8

Gene

Rps8

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S8
Gene namesi
Name:Rps8
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:98166 Rps8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001222412 – 20840S ribosomal protein S8Add BLAST207

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineBy similarity1
Modified residuei37N6-acetyllysineCombined sources1
Modified residuei128N6-acetyllysineCombined sources1
Modified residuei130PhosphothreonineCombined sources1
Modified residuei160PhosphoserineBy similarity1
Cross-linki170Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki193Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Lipoprotein, Myristate, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiP62242
PaxDbiP62242
PeptideAtlasiP62242
PRIDEiP62242
TopDownProteomicsiP62242

PTM databases

iPTMnetiP62242
PhosphoSitePlusiP62242
SwissPalmiP62242

Expressioni

Gene expression databases

BgeeiENSMUSG00000047675
CleanExiMM_RPS8
ExpressionAtlasiP62242 baseline and differential
GenevisibleiP62242 MM

Interactioni

Subunit structurei

Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.By similarity

Protein-protein interaction databases

BioGridi203017, 2 interactors
CORUMiP62242
IntActiP62242, 6 interactors
MINTiP62242
STRINGi10090.ENSMUSP00000099757

Structurei

3D structure databases

ProteinModelPortaliP62242
SMRiP62242
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3283 Eukaryota
COG2007 LUCA
GeneTreeiENSGT00390000012433
HOGENOMiHOG000211544
HOVERGENiHBG030738
InParanoidiP62242
KOiK02995
OMAiAWGSEHV
OrthoDBiEOG091G0MF7
PhylomeDBiP62242
TreeFamiTF300041

Family and domain databases

InterProiView protein in InterPro
IPR001047 Ribosomal_S8e
IPR022309 Ribosomal_S8e/biogenesis_NSA2
IPR018283 Ribosomal_S8e_CS
PANTHERiPTHR10394 PTHR10394, 1 hit
PfamiView protein in Pfam
PF01201 Ribosomal_S8e, 1 hit
TIGRFAMsiTIGR00307 eS8, 1 hit
PROSITEiView protein in PROSITE
PS01193 RIBOSOMAL_S8E, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P62242-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGISRDNWHK RRKTGGKRKP YHKKRKYELG RPAANTKIGP RRIHTVRVRG
60 70 80 90 100
GNKKYRALRL DVGNFSWGSE CCTRKTRIID VVYNASNNEL VRTKTLVKNC
110 120 130 140 150
IVLIDSTPYR QWYESHYALP LGRKKGAKLT PEEEEILNKK RSKKIQKKYD
160 170 180 190 200
ERKKNAKISS LLEEQFQQGK LLACIASRPG QCGRADGYVL EGKELEFYLR

KIKARKGK
Length:208
Mass (Da):24,205
Last modified:January 23, 2007 - v2
Checksum:i407FDF59171F7422
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti70E → V in BAC40485 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73829 mRNA Translation: CAA52050.1
AK009023 mRNA Translation: BAB26032.1
AK010650 mRNA Translation: BAB27090.1
AK011048 mRNA Translation: BAB27359.1
AK011058 mRNA Translation: BAB27366.1
AK011642 mRNA Translation: BAB27754.1
AK012435 mRNA Translation: BAB28236.1
AK012665 mRNA Translation: BAB28394.1
AK088660 mRNA Translation: BAC40485.1
BC027217 mRNA Translation: AAH27217.1
BC051446 mRNA Translation: AAH51446.1
BC081465 mRNA Translation: AAH81465.1
CCDSiCCDS18530.1
PIRiS42110
RefSeqiNP_033124.1, NM_009098.2
UniGeneiMm.260904
Mm.338718

Genome annotation databases

EnsembliENSMUST00000102696; ENSMUSP00000099757; ENSMUSG00000047675
GeneIDi20116
KEGGimmu:20116
UCSCiuc008uic.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRS8_MOUSE
AccessioniPrimary (citable) accession number: P62242
Secondary accession number(s): P09058, Q8C2G6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 127 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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