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Protein

40S ribosomal protein S7

Gene

Rps7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for rRNA maturation.By similarity

GO - Molecular functioni

  • poly(U) RNA binding Source: RGD
  • structural constituent of ribosome Source: InterPro

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S7
Alternative name(s):
S8
Gene namesi
Name:Rps7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi61907 Rps7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001741921 – 19440S ribosomal protein S7Add BLAST194

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionine1 Publication1
Cross-linki70Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei74N6-acetyllysine; alternateBy similarity1
Cross-linki74Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity

Post-translational modificationi

Phosphorylated by NEK6.By similarity
Ubiquitinated. Deubiquitinated by DESI2, leading to its stabilization.By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiP62083
PRIDEiP62083

PTM databases

iPTMnetiP62083
PhosphoSitePlusiP62083
SwissPalmiP62083

Expressioni

Gene expression databases

BgeeiENSRNOG00000008551
ExpressionAtlasiP62083 baseline and differential
GenevisibleiP62083 RN

Interactioni

Subunit structurei

Binds IPO9 with high affinity. Interacts with NEK6. Interacts with DESI2.By similarity

Protein-protein interaction databases

BioGridi247931, 1 interactor
IntActiP62083, 2 interactors
STRINGi10116.ENSRNOP00000011545

Structurei

3D structure databases

ProteinModelPortaliP62083
SMRiP62083
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi98 – 120Arg/Lys-rich (basic)Add BLAST23

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3320 Eukaryota
ENOG410ZYKB LUCA
GeneTreeiENSGT00390000014122
HOGENOMiHOG000197237
HOVERGENiHBG001698
InParanoidiP62083
KOiK02993
OMAiGFHRVQQ
OrthoDBiEOG091G0L94
PhylomeDBiP62083
TreeFamiTF343364

Family and domain databases

InterProiView protein in InterPro
IPR000554 Ribosomal_S7e
PANTHERiPTHR11278 PTHR11278, 1 hit
PfamiView protein in Pfam
PF01251 Ribosomal_S7e, 1 hit
PROSITEiView protein in PROSITE
PS00948 RIBOSOMAL_S7E, 1 hit

Sequencei

Sequence statusi: Complete.

P62083-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSSSAKIVK PNGEKPDEFE SGISQALLEL EMNSDLKAQL RELNITAAKE
60 70 80 90 100
IEVGGGRKAI IIFVPVPQLK SFQKIQVRLV RELEKKFSGK HVVFIAQRRI
110 120 130 140 150
LPKPTRKSRT KNKQKRPRSR TLTAVHDAIL EDLVFPSEIV GKRIRVKLDG
160 170 180 190
SRLIKVHLDK AQQNNVEHKV ETFSGVYKKL TGKDVNFEFP EFQL
Length:194
Mass (Da):22,127
Last modified:June 21, 2004 - v1
Checksum:iE21089929CC061E9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti2F → S in CAA40177 (PubMed:2030949).Curated1
Sequence conflicti14 – 16EKP → KKR in CAA40177 (PubMed:2030949).Curated3
Sequence conflicti35D → E in CAA40177 (PubMed:2030949).Curated1
Sequence conflicti38A → T in CAA40177 (PubMed:2030949).Curated1
Sequence conflicti41R → W in CAA40177 (PubMed:2030949).Curated1
Sequence conflicti75 – 79IQVRL → MAKSGK in CAA40177 (PubMed:2030949).Curated5
Sequence conflicti149D → V in CAA40177 (PubMed:2030949).Curated1
Sequence conflicti180 – 181LT → PL in CAA40177 (PubMed:2030949).Curated2
Sequence conflicti192 – 194FQL → VSV in CAA40177 (PubMed:2030949).Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53377 mRNA Translation: CAA37457.1
X56846 mRNA Translation: CAA40177.1
BC060557 mRNA Translation: AAH60557.1
PIRiS12862 R3RT7
RefSeqiNP_113758.2, NM_031570.2
XP_002726666.2, XM_002726620.5
XP_002729622.2, XM_002729576.5
UniGeneiRn.107039
Rn.224475

Genome annotation databases

EnsembliENSRNOT00000011333; ENSRNOP00000011333; ENSRNOG00000008551
ENSRNOT00000092867; ENSRNOP00000075995; ENSRNOG00000008551
GeneIDi100362830
29258
KEGGirno:100362830
rno:29258

Similar proteinsi

Entry informationi

Entry nameiRS7_RAT
AccessioniPrimary (citable) accession number: P62083
Secondary accession number(s): P23821, P24818
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 21, 2004
Last sequence update: June 21, 2004
Last modified: May 23, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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