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Entry version 159 (18 Sep 2019)
Sequence version 1 (21 Jun 2004)
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Protein

40S ribosomal protein S7

Gene

RPS7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for rRNA maturation.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

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Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6790901 rRNA modification in the nucleus and cytosol
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649 Translation initiation complex formation
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Protein family/group databases

MoonProt database of moonlighting proteins

More...
MoonProti
P62081

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S7
Alternative name(s):
Small ribosomal subunit protein eS71 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPS7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10440 RPS7

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603658 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P62081

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Diamond-Blackfan anemia 8 (DBA8)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Related information in OMIM

Keywords - Diseasei

Diamond-Blackfan anemia

Organism-specific databases

DisGeNET

More...
DisGeNETi
6201

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
RPS7

MalaCards human disease database

More...
MalaCardsi
RPS7
MIMi612563 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000171863

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
124 Blackfan-Diamond anemia

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34855

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPS7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
49065831

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001741901 – 19440S ribosomal protein S7Add BLAST194

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki70Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei74N6-acetyllysine; alternateCombined sources1
Cross-linki74Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by NEK6.1 Publication
Ubiquitinated. Deubiquitinated by DESI2, leading to its stabilization.1 Publication

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
P62081

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P62081

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
P62081

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P62081

PeptideAtlas

More...
PeptideAtlasi
P62081

PRoteomics IDEntifications database

More...
PRIDEi
P62081

ProteomicsDB human proteome resource

More...
ProteomicsDBi
57364

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P62081

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P62081

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P62081

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P62081

Miscellaneous databases

CutDB - Proteolytic event database

More...
PMAP-CutDBi
P62081

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000171863 Expressed in 90 organ(s), highest expression level in female gonad

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P62081 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P62081 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA056586

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds IPO9 with high affinity (PubMed:11823430).

Interacts with NEK6 (PubMed:20873783).

Interacts with DESI2 (PubMed:28483520).

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112115, 215 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P62081

Protein interaction database and analysis system

More...
IntActi
P62081, 55 interactors

Molecular INTeraction database

More...
MINTi
P62081

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000339095

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P62081

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi98 – 120Arg/Lys-rich (basic)Add BLAST23

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3320 Eukaryota
ENOG410ZYKB LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014122

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000197237

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P62081

KEGG Orthology (KO)

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KOi
K02993

Identification of Orthologs from Complete Genome Data

More...
OMAi
WHKAQQR

Database of Orthologous Groups

More...
OrthoDBi
664798at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P62081

TreeFam database of animal gene trees

More...
TreeFami
TF343364

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000554 Ribosomal_S7e

The PANTHER Classification System

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PANTHERi
PTHR11278 PTHR11278, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01251 Ribosomal_S7e, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00948 RIBOSOMAL_S7E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P62081-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFSSSAKIVK PNGEKPDEFE SGISQALLEL EMNSDLKAQL RELNITAAKE
60 70 80 90 100
IEVGGGRKAI IIFVPVPQLK SFQKIQVRLV RELEKKFSGK HVVFIAQRRI
110 120 130 140 150
LPKPTRKSRT KNKQKRPRSR TLTAVHDAIL EDLVFPSEIV GKRIRVKLDG
160 170 180 190
SRLIKVHLDK AQQNNVEHKV ETFSGVYKKL TGKDVNFEFP EFQL
Length:194
Mass (Da):22,127
Last modified:June 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE21089929CC061E9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B5MCP9B5MCP9_HUMAN
40S ribosomal protein S7
RPS7
187Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Y623A0A2R8Y623_HUMAN
40S ribosomal protein S7
RPS7
169Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M77233 mRNA Translation: AAB00969.1
Z25749 Genomic DNA Translation: CAA81022.1
AK311794 mRNA Translation: BAG34737.1
AC108488 Genomic DNA Translation: AAX82027.1
CH471053 Genomic DNA Translation: EAX01057.1
CH471053 Genomic DNA Translation: EAX01058.1
CH471053 Genomic DNA Translation: EAX01059.1
BC002866 mRNA Translation: AAH02866.1
BC061901 mRNA Translation: AAH61901.1
BC071919 mRNA Translation: AAH71919.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1648.1

Protein sequence database of the Protein Information Resource

More...
PIRi
JC4388

NCBI Reference Sequences

More...
RefSeqi
NP_001002.1, NM_001011.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000403564; ENSP00000385018; ENSG00000171863
ENST00000406376; ENSP00000385286; ENSG00000171863
ENST00000462576; ENSP00000495273; ENSG00000171863
ENST00000645674; ENSP00000496757; ENSG00000171863
ENST00000646909; ENSP00000496654; ENSG00000171863

Database of genes from NCBI RefSeq genomes

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GeneIDi
6201

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6201

UCSC genome browser

More...
UCSCi
uc002qxw.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M77233 mRNA Translation: AAB00969.1
Z25749 Genomic DNA Translation: CAA81022.1
AK311794 mRNA Translation: BAG34737.1
AC108488 Genomic DNA Translation: AAX82027.1
CH471053 Genomic DNA Translation: EAX01057.1
CH471053 Genomic DNA Translation: EAX01058.1
CH471053 Genomic DNA Translation: EAX01059.1
BC002866 mRNA Translation: AAH02866.1
BC061901 mRNA Translation: AAH61901.1
BC071919 mRNA Translation: AAH71919.1
CCDSiCCDS1648.1
PIRiJC4388
RefSeqiNP_001002.1, NM_001011.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-SH1-194[»]
4V6Xelectron microscopy5.00AH1-194[»]
5A2Qelectron microscopy3.90H1-194[»]
5AJ0electron microscopy3.50BH1-194[»]
5FLXelectron microscopy3.90H1-194[»]
5LKSelectron microscopy3.60SH1-194[»]
5OA3electron microscopy4.30H1-194[»]
5T2Celectron microscopy3.60At1-194[»]
5VYCX-ray6.00H1/H2/H3/H4/H5/H61-194[»]
6EK0electron microscopy2.90SH1-194[»]
6FECelectron microscopy6.30X5-194[»]
6G18electron microscopy3.60H1-194[»]
6G4Selectron microscopy4.00H1-194[»]
6G4Welectron microscopy4.50H1-194[»]
6G51electron microscopy4.10H1-194[»]
6G53electron microscopy4.50H1-194[»]
6G5Helectron microscopy3.60H1-194[»]
6G5Ielectron microscopy3.50H1-194[»]
6IP5electron microscopy3.902s1-194[»]
6IP6electron microscopy4.502s1-194[»]
6IP8electron microscopy3.902s1-194[»]
6OLEelectron microscopy3.10SH5-193[»]
6OLFelectron microscopy3.90SH5-193[»]
6OLGelectron microscopy3.40BH12-194[»]
6OLIelectron microscopy3.50SH5-193[»]
6OLZelectron microscopy3.90BH12-194[»]
6OM0electron microscopy3.10SH5-193[»]
6OM7electron microscopy3.70SH5-193[»]
6QZPelectron microscopy2.90SH5-193[»]
SMRiP62081
ModBaseiSearch...

Protein-protein interaction databases

BioGridi112115, 215 interactors
CORUMiP62081
IntActiP62081, 55 interactors
MINTiP62081
STRINGi9606.ENSP00000339095

Protein family/group databases

MoonProtiP62081

PTM databases

iPTMnetiP62081
PhosphoSitePlusiP62081
SwissPalmiP62081

Polymorphism and mutation databases

BioMutaiRPS7
DMDMi49065831

Proteomic databases

EPDiP62081
jPOSTiP62081
MassIVEiP62081
PaxDbiP62081
PeptideAtlasiP62081
PRIDEiP62081
ProteomicsDBi57364
TopDownProteomicsiP62081

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6201
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000403564; ENSP00000385018; ENSG00000171863
ENST00000406376; ENSP00000385286; ENSG00000171863
ENST00000462576; ENSP00000495273; ENSG00000171863
ENST00000645674; ENSP00000496757; ENSG00000171863
ENST00000646909; ENSP00000496654; ENSG00000171863
GeneIDi6201
KEGGihsa:6201
UCSCiuc002qxw.4 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
6201
DisGeNETi6201

GeneCards: human genes, protein and diseases

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GeneCardsi
RPS7
GeneReviewsiRPS7
HGNCiHGNC:10440 RPS7
HPAiHPA056586
MalaCardsiRPS7
MIMi603658 gene
612563 phenotype
neXtProtiNX_P62081
OpenTargetsiENSG00000171863
Orphaneti124 Blackfan-Diamond anemia
PharmGKBiPA34855

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3320 Eukaryota
ENOG410ZYKB LUCA
GeneTreeiENSGT00390000014122
HOGENOMiHOG000197237
InParanoidiP62081
KOiK02993
OMAiWHKAQQR
OrthoDBi664798at2759
PhylomeDBiP62081
TreeFamiTF343364

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6790901 rRNA modification in the nucleus and cytosol
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649 Translation initiation complex formation
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
RPS7 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
RPS7

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
6201

Pharos

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Pharosi
P62081
PMAP-CutDBiP62081

Protein Ontology

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PROi
PR:P62081

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000171863 Expressed in 90 organ(s), highest expression level in female gonad
ExpressionAtlasiP62081 baseline and differential
GenevisibleiP62081 HS

Family and domain databases

InterProiView protein in InterPro
IPR000554 Ribosomal_S7e
PANTHERiPTHR11278 PTHR11278, 1 hit
PfamiView protein in Pfam
PF01251 Ribosomal_S7e, 1 hit
PROSITEiView protein in PROSITE
PS00948 RIBOSOMAL_S7E, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS7_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62081
Secondary accession number(s): P23821
, P24818, Q57Z92, Q6IPH1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 21, 2004
Last sequence update: June 21, 2004
Last modified: September 18, 2019
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Ribosomal proteins
    Ribosomal proteins families and list of entries
UniProt is an ELIXIR core data resource
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