UniProtKB - P62001 (TBP_PYRWO)
Protein
TATA-box-binding protein
Gene
tbp
Organism
Pyrococcus woesei
Status
Functioni
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: UniProtKB-UniRule
GO - Biological processi
- DNA-templated transcription, initiation Source: InterPro
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: TATA-box-binding proteinAlternative name(s): Box A-binding protein Short name: BAP TATA sequence-binding protein Short name: TBP TATA-box factor |
Gene namesi | Name:tbp |
Organismi | Pyrococcus woesei |
Taxonomic identifieri | 2262 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000154023 | 1 – 191 | TATA-box-binding proteinAdd BLAST | 191 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P62001 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P62001 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 11 – 87 | 1Add BLAST | 77 | |
Repeati | 102 – 178 | 2Add BLAST | 77 |
Sequence similaritiesi
Belongs to the TBP family.Curated
Keywords - Domaini
RepeatFamily and domain databases
CDDi | cd04518, TBP_archaea, 1 hit |
Gene3Di | 3.30.310.10, 2 hits |
HAMAPi | MF_00408, TATA_bind_prot_arch, 1 hit |
InterProi | View protein in InterPro IPR000814, TBP IPR033711, TBP_archaea IPR030491, TBP_CS IPR012295, TBP_dom_sf |
PANTHERi | PTHR10126, PTHR10126, 1 hit |
Pfami | View protein in Pfam PF00352, TBP, 2 hits |
PRINTSi | PR00686, TIFACTORIID |
PROSITEi | View protein in PROSITE PS00351, TFIID, 2 hits |
i Sequence
Sequence statusi: Complete.
P62001-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVDMSKVKLR IENIVASVDL FAQLDLEKVL DLCPNSKYNP EEFPGIICHL
60 70 80 90 100
DDPKVALLIF SSGKLVVTGA KSVQDIERAV AKLAQKLKSI GVKFKRAPQI
110 120 130 140 150
DVQNMVFSGD IGREFNLDVV ALTLPNCEYE PEQFPGVIYR VKEPKSVILL
160 170 180 190
FSSGKIVCSG AKSEADAWEA VRKLLRELDK YGLLEEEEEE L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U10285 Unassigned DNA Translation: AAA73447.1 |
PIRi | A54275 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U10285 Unassigned DNA Translation: AAA73447.1 |
PIRi | A54275 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1AIS | X-ray | 2.10 | A | 1-181 | [»] | |
1D3U | X-ray | 2.40 | A | 1-181 | [»] | |
1PCZ | X-ray | 2.20 | A/B | 1-191 | [»] | |
SMRi | P62001 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P62001 |
Family and domain databases
CDDi | cd04518, TBP_archaea, 1 hit |
Gene3Di | 3.30.310.10, 2 hits |
HAMAPi | MF_00408, TATA_bind_prot_arch, 1 hit |
InterProi | View protein in InterPro IPR000814, TBP IPR033711, TBP_archaea IPR030491, TBP_CS IPR012295, TBP_dom_sf |
PANTHERi | PTHR10126, PTHR10126, 1 hit |
Pfami | View protein in Pfam PF00352, TBP, 2 hits |
PRINTSi | PR00686, TIFACTORIID |
PROSITEi | View protein in PROSITE PS00351, TFIID, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TBP_PYRWO | |
Accessioni | P62001Primary (citable) accession number: P62001 Secondary accession number(s): Q57050 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2004 |
Last sequence update: | June 7, 2004 | |
Last modified: | December 11, 2019 | |
This is version 72 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families